Protein Alignment Sytalpha and SYT2

DIOPT Version :9

• Sequence 1: NP_001188832.1
• Gene: Sytalpha / 35068
• FlyBaseID: FBgn0261089
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: XP_016855798.1
• Gene: SYT2 / 127833
• HGNCID: 11510
• Length: 479
• Species: Homo sapiens
• Alignment Length: 270
• Identity: 100/270 - (37%)
• Similarity: 162/270 - (60%)
• Gaps: 4/270 - (1%)

  Fly   220 GNLHVSLGYDPVGGLLNVRLLEAQNLQPRQFSGTADPYAKVRLLPDKKNFWQTRIHKRTLNPVFD 284
            |.|..||.||.....|.|.:|:|..|......||:|||.||.||||||..::|::|::||||.|:
Human   201 GKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKKKYETKVHRKTLNPAFN 265

  Fly   285 EQFVFEVTAGVIDKRTVEILLYDFDAYSRHVCIGGSKLHLANLDLSEQLKLWTPLSSASAQDMKV 349
            |.|.|:|....:..:|:.:.:||||.:|:|..||..|:.:..:||.:.::.|..|.....::.:
Human   266 ETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEWRDLQGGEKEEPE- 329

  Fly   350 DLGDIMVSLAYLPSAERLMVVLIKARNLRIVDDARNSSDPYVKVTLLGPGGKKIKKRKTGVQRGT 414
            .||||..||.|:|:|.:|.|.:::|:||:.: |....||||||:.|: ..||::||:||.|::.|
Human   330 KLGDICTSLRYVPTAGKLTVCILEAKNLKKM-DVGGLSDPYVKIHLM-QNGKRLKKKKTTVKKKT 392

  Fly   415 LNPVYNEALAFDVAKETLKNCVLEFTVVHDGLLGSSEILGRTLIGNSPEVRTEEKIFFEEVFRAK 479
            |||.:||:.:|::..|.::...:..||:....||.:|.:|:..:| |....||.:.:.:.:...:
Human   393 LNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVG-SNATGTELRHWSDMLANPR 456

  Fly   480 NATAQWVPLQ 489
            ...|||..|:
Human   457 RPIAQWHSLK 466

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sytalpha	NP_001188832.1	C2A_Synaptotagmin-8	218..341	CDD:176033	49/120 (41%)
		C2B_Synaptotagmin	352..488	CDD:175975	49/135 (36%)
SYT2	XP_016855798.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1028
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D925064at2759
OrthoFinder	1	1.000	-	-		FOG0000025
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.820