Protein Alignment Sytalpha and Syt17

DIOPT Version :10

• Sequence 1: NP_001188832.1
• Gene: Sytalpha / 35068
• FlyBaseID: FBgn0261089
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_001390574.1
• Gene: Syt17 / 110058
• MGIID: 104966
• Length: 474
• Species: Mus musculus
• Alignment Length: 446
• Identity: 138/446 - (30%)
• Similarity: 220/446 - (49%)
• Gaps: 67/446 - (15%)

  Fly    64 ANEKDEDQQREALVAGAVGYNVDNVNEVPRGKYSSGNAGNLSPTSLKSEDNDPAFWVPASVT--S 126
            :|:||.|             :|...::||           |:|.:     |.|.....:|.|  |
Mouse    66 SNDKDGD-------------SVHTASDVP-----------LTPRT-----NSPDGRRSSSDTSKS 101

  Fly   127 TAAIQQQVSNTTEESAPPTSPTGSLKSNTLSYCSTTSVPIARSDKHVVLA--------MHPSRPR 183
            |.::.:::|:.  :|..|:||...:|.......|.....|..|    ||.        .....||
Mouse   102 TYSLTRRISSL--DSRRPSSPLIDIKPVEFGVLSAKKESIQPS----VLRRTYTPDDYFRKFEPR 160

  Fly   184 VSSMNAKLDHTKIDMTLYRSHSQPKTINPVSLNEVRGNLHVSLGYDPVGGLLNVRLLEAQNLQP- 247
            :.|:::.||  .:|     |.:..:.::...|    |.||.|..||.:...|.||::||::|.|
Mouse   161 LYSLDSNLD--DVD-----SLTDEEIMSKYQL----GMLHFSTQYDLLHNHLTVRVIEARDLPPP 214

  Fly   248 ------RQFSGTADPYAKVRLLPDKKNFWQTRIHKRTLNPVFDEQFVFEVTAGVIDKRTVEILLY 306
                  ||....::||.|:.||||:||..||.:.::|..|||:|::.||:......:||:.:.:.
Mouse   215 ISHDGSRQDMAHSNPYVKICLLPDQKNSKQTGVKRKTQKPVFEERYTFEIPFLEAQRRTLLLTVV 279

  Fly   307 DFDAYSRHVCIGGSKLHLANLDLSEQLKLWTPLSSASAQDMKVDLGDIMVSLAYLPSAERLMVVL 371
            |||.:|||..||...:.|..:||.:....|..|..:|..:  |:||::::||.|||||.||.|.:
Mouse   280 DFDKFSRHCVIGKVAVPLCEVDLVKGGHWWKALIPSSQNE--VELGELLLSLNYLPSAGRLNVDI 342

  Fly   372 IKARNLRIVDDARNSSDPYVKVTLLGPGGKKIKKRKTGVQRGTLNPVYNEALAFDVAKETLKNCV 436
            |:|:.| :..|....|||:||:.|: .|.|.:|.:||...|||::|.|||:.:|.|.:|.|:|..
Mouse   343 IRAKQL-LQTDVSQGSDPFVKIQLV-HGLKLVKTKKTSFLRGTIDPFYNESFSFKVPQEELENAS 405

  Fly   437 LEFTVVHDGLLGSSEILGRTLIGNSPEVRTEEKIFFEEVFRAKNATAQWVPLQEPA 492
            |.|||....:..|::.:||.:||......:|...:...:...:.|..||..|:..|
Mouse   406 LVFTVFGHNMKSSNDFIGRIVIGQYSSGPSESNHWRRMLNTHRTAVEQWHSLRSRA 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sytalpha	NP_001188832.1	C2A_Synaptotagmin-8	218..341	CDD:176033	48/129 (37%)
		C2B_Synaptotagmin	352..488	CDD:175975	51/135 (38%)
Syt17	NP_001390574.1	C2A_Synaptotagmin-15-17	186..314	CDD:176036	48/127 (38%)
		C2B_Synaptotagmin-17	323..457	CDD:176055	51/135 (38%)