Protein Alignment Sytalpha and sytl4

DIOPT Version :10

• Sequence 1: NP_001188832.1
• Gene: Sytalpha / 35068
• FlyBaseID: FBgn0261089
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: XP_031746962.1
• Gene: sytl4 / 100495134
• XenbaseID: XB-GENE-958567
• Length: 692
• Species: Xenopus tropicalis
• Alignment Length: 552
• Identity: 134/552 - (24%)
• Similarity: 214/552 - (38%)
• Gaps: 153/552 - (27%)

  Fly    47 CSKRYRL-----NWF-EQNLLESANEKDEDQQREAL-----------VAGAVGYNVDNVNE---- 90
            |||...|     :|| :|.:...||....|..|.:|           .|.|:......:||
 Frog   110 CSKEADLKKSTGDWFYDQRVNRFANRLGRDMVRMSLRQKPSANKRETTAQALLEFSQQLNEPKTR 174

  Fly    91 ----VPRGKYSSGNAGNLSPTSLKSEDNDPAFWVPASVTSTAAIQQQVSNTTEESAPPTSPTGSL 151
                .|:.::.|..    || .|:.:.:|.......|::|       ....:::|:|.||...||
 Frog   175 KAQRSPQQQHKSSG----SP-DLRDQKSDTESTEQMSLSS-------YKTDSKKSSPSTSRRNSL 227

  Fly   152 -KSNTL-----------SYCSTTSVPIARSDKH-------------------------------- 172
             ||.||           :..:|.:||:...|:|
 Frog   228 EKSATLQDAKRAQGPVGANVATLTVPVRSRDRHQSDSEGEALLGSRSAGSADESDTLFKKNPRRL 292

  Fly   173 --------VVLAMHPSRPRVSSMNAKLDHTK------IDM--------------------TLYRS 203
                    .||.:.| .|.....||..|.:|      |:|                    :..||
 Frog   293 LKPADYSKSVLDLRP-EPAAPEENALGDRSKSVPRLNIEMEEEDEDIDNLVEIHRLSAGRSSLRS 356

  Fly   204 HSQPKTI-NPVSLNE---------VRGNLHVSLGYDPVGGLLNVRLLEAQNL-QPRQFSGTADPY 257
            .:...|: :.:|:..         :.|.:..|:.||....|||:.:.|.:|| ...:....::||
 Frog   357 GASSSTLGSMISIYSEAGDFGNVIITGEIIFSINYDAKVQLLNILVKECRNLAYGDELKMRSNPY 421

  Fly   258 AKVRLLPDK--KNFWQTRIHKRTLNPVFDEQFVFEVTAGVIDKRTVEILLYDFDAYSRHVCIGGS 320
            .|..|||||  :...:|.|.:.|.||:::|...:.|...::..|::|:.::.:|.:.|:..:|..
 Frog   422 IKSYLLPDKSRQGKRKTTIKRNTTNPMYNEVLKYIVPESMLHLRSLELSVWHYDRFGRNTFLGQV 486

  Fly   321 KLHLANLDLSEQLKLWTPLSSASAQDMKVDL----GDIMVSLAYLP-----SAER---------- 366
            .:.|.:.:....::...||......|.....    |:::|||.|:|     .:||
 Frog   487 DIPLDSWNFDSLIEECLPLHGKGNMDSGAGFYNSKGELVVSLKYVPPTKPSGSERRKKKADEGGE 551

  Fly   367 LMVVLIKARNLRIVDDARNSSDPYVKVTLLGPGGKKIKKRKTGVQRGTLNPVYNEALAFD-VAKE 430
            |.|.:.:|:||..|... ..||.:||..|. |...|..||||.|.:.||||.||....:: :..|
 Frog   552 LHVWIKEAKNLTAVKTG-GISDSFVKGYLF-PHKNKNTKRKTPVVKKTLNPHYNHTFVYNGIKPE 614

  Fly   431 TLKNCVLEFTVVHDGLLGSSEILG--RTLIGN 460
            .|:|..||.||.....|.|::.||  |..|||
 Frog   615 DLQNVCLELTVWDREPLSSNDFLGGVRLGIGN 646

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sytalpha	NP_001188832.1	C2A_Synaptotagmin-8	218..341	CDD:176033	33/125 (26%)
		C2B_Synaptotagmin	352..488	CDD:175975	47/127 (37%)
sytl4	XP_031746962.1	PHD_SF	15..126	CDD:473978	6/15 (40%)
		FYVE_Slp4	63..112	CDD:277303	1/1 (100%)
		C2A_SLP-4_5	382..506	CDD:175995	32/123 (26%)
		C2B_SLP_1-2-3-4	521..685	CDD:175987	47/128 (37%)