DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sytalpha and syt8

DIOPT Version :9

Sequence 1:	NP_001188832.1	Gene:	Sytalpha / 35068	FlyBaseID:	FBgn0261089	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	XP_012815834.1	Gene:	syt8 / 100037878	XenbaseID:	XB-GENE-978920	Length:	396	Species:	Xenopus tropicalis

Alignment Length:	316	Identity:	103/316 - (32%)
Similarity:	170/316 - (53%)	Gaps:	17/316 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   185 SSMNAKLDHTKIDMTLYRSHSQPKTINPVSLN-------EVRGNLHVSLGYDPVGGLLNVRLLEA 242
            |..|.|....||||.....:.....:.|.:.|       |.||.:..||.|:.....|.|.:.:|
Frog    65 SKKNKKKKDKKIDMDKVPGNLTTHLVQPGAGNLQKGEKVEYRGRVQYSLEYNFQTEELTVGVKQA 129

  Fly   243 QNLQPRQFSGTADPYAKVRLLPDKKNFWQTRIHKRTLNPVFDEQFVFEVTAGVIDKRTVEILLYD 307
            ..|:.....||:||||.|.:..|.:..::|:::::||||||:|.|||:||...:.:.|..:.::|
Frog   130 AALKAMDLGGTSDPYAIVYVTNDTRKKFETKVNRKTLNPVFNESFVFKVTQEEVPRTTAVVQIFD 194

  Fly   308 FDAYSRHVCIGGSKLHLANLDLSEQLKLWTPLSSASAQDMKVDLGDIMVSLAYLPSAERLMVVLI 372
            |:.:.:|..||...:.|..::|...::.|..|..|...:.: .||||..||.|:||:.:|.::::
Frog   195 FNRFLKHDVIGEMVIPLGEVNLQHVIEDWKDLGPAGKTEHE-HLGDICFSLRYVPSSGKLTIIIL 258

  Fly   373 KARNLRIVDDARNSSDPYVKVTLLGPGGKKIKKRKTGVQRGTLNPVYNEALAFDVAKETLKNCVL 437
            :|:||:.: |:...|||||||. |....||.|::||.|::.||.|.:||:..|||:.|.:||..|
Frog   259 EAKNLKRM-DSDGFSDPYVKVH-LALNRKKWKRKKTAVKKSTLKPYFNESFTFDVSLEQMKNLDL 321

  Fly   438 EFTVVHDGLLGSSEILGRTLIG---NSPEVRTEEKIFFEEVFRAKNATAQWVPLQE 490
            ..:|.....:|.:|.:|:..:|   :...:|.    :.:.:...:...|||..|||
Frog   322 IISVWDHDKVGKNEQIGKLFLGCRASGNALRH----WSDMLAHPRRPIAQWHKLQE 373

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sytalpha	NP_001188832.1	C2A_Synaptotagmin-8	218..341	CDD:176033	40/122 (33%)
Sytalpha	NP_001188832.1	C2B_Synaptotagmin	352..488	CDD:175975	48/138 (35%)
syt8	XP_012815834.1	C2A_Synaptotagmin-1-5-6-9-10	105..228	CDD:176031	40/122 (33%)
syt8	XP_012815834.1	C2B_Synaptotagmin-1	237..372	CDD:176047	49/140 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D925064at2759
OrthoFinder	1	1.000	-	-		FOG0000025
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920