Protein Alignment Sytalpha and syt3

DIOPT Version :9

• Sequence 1: NP_001188832.1
• Gene: Sytalpha / 35068
• FlyBaseID: FBgn0261089
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: XP_005164031.1
• Gene: syt3 / 100000615
• ZFINID: ZDB-GENE-090601-1
• Length: 566
• Species: Danio rerio
• Alignment Length: 540
• Identity: 144/540 - (26%)
• Similarity: 234/540 - (43%)
• Gaps: 134/540 - (24%)

  Fly     3 THSLSAGEMDIVIREEDISLAQIGVYASVSFL--VVSAVGAALYT-TCSKRYRLNWFEQNLLESA 64
            :.|.|..|...::|..:   .||....|||.|  :|:..|..|.: :....::|.|...
Zfish    28 SQSASCQEFSYMMRGPN---RQINTEISVSLLSVIVTFCGIVLLSVSLFVSWKLCWLPW------ 83

  Fly    65 NEKDED----QQREALVAGAVGYNVDNVNEVPRGKYSSGNAGNLSPTSLKSEDNDPAFWVPASVT 125
              :|::    .....|:.|..|.          |....|...:|.|..|:.:|...:    :|:.
Zfish    84 --RDKEGGGLSLTSGLLPGGAGL----------GGVGGGGGASLLPPLLQRKDTHSS----SSLY 132

  Fly   126 STAAIQQQ------------------------------------------------VSNTTEESA 142
            .|.:.|.|                                                :|.|:.| .
Zfish   133 PTLSQQGQHHPHFSDVMGVEGGGGLVVGGVVGGPQEMQEHSYLDMDSYPNNAATLKLSQTSPE-L 196

  Fly   143 PPTSPTGSLKSNTLSYCSTTSVPIARSDKHVVLAMHPSRPRVSSMNAKLDHTKIDMTLYRSHSQP 207
            ||.:..||         :...:|.|.|.:.|.....|...::||.:              .|.:.
Zfish   197 PPATEGGS---------AAKDLPNAHSQQQVTTRPKPMTHQLSSPD--------------FHGEE 238

  Fly   208 KTINPVSLNEVR--------------------GNLHVSLGYDPVGGLLNVRLLEAQNLQPRQFSG 252
            |:....|:.:::                    |.:...|.|......|.|::|:|.:|..:..:|
Zfish   239 KSEQLTSIGQIKPELYRLRQGDQGDGKQGNNCGKISFLLRYAFNTEQLVVKILKALDLPAKDANG 303

  Fly   253 TADPYAKVRLLPDKKNFWQTRIHKRTLNPVFDEQFVFEVTAGVIDKRTVEILLYDFDAYSRHVCI 317
            .:|||.|:.||||:|..:||::|::||||||:|.|.|.|....:..|.:...:||||.:|||..|
Zfish   304 FSDPYVKIYLLPDRKKKFQTKVHRKTLNPVFNETFQFGVPLAELHARKLHFSVYDFDRFSRHDLI 368

  Fly   318 GGSKLHLAN-LDLSE---QLKLWTPLSSASAQDMKVDLGDIMVSLAYLPSAERLMVVLIKARNLR 378
            |  ::.:.| ||.||   :..:|..:...:|:  |.|||::..||.|||:|.||.|.:|||.||:
Zfish   369 G--QVVVDNLLDFSEGTGEKPIWRDIVEGTAE--KADLGELNFSLCYLPTAGRLTVTIIKATNLK 429

  Fly   379 IVDDARNSSDPYVKVTLLGPGGKKIKKRKTGVQRGTLNPVYNEALAFDVAKETLKNCVLEFTVVH 443
            .: |....||||||.:|:.. |:::|||||.:::.||||.|||||.||:..|.:::..|...|:.
Zfish   430 AM-DLTGFSDPYVKASLVCE-GRRLKKRKTSIKKNTLNPTYNEALVFDIPNENIESVSLIIAVMD 492

  Fly   444 DGLLGSSEILGRTLIGNSPE 463
            ...:|.:|::|...:|:..:
Zfish   493 YDCIGHNEVIGMCRMGSDAD 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sytalpha	NP_001188832.1	C2A_Synaptotagmin-8	218..341	CDD:176033	47/146 (32%)
		C2B_Synaptotagmin	352..488	CDD:175975	47/112 (42%)
syt3	XP_005164031.1	C2A_Synaptotagmin-1-5-6-9-10	269..394	CDD:176031	47/126 (37%)
		C2B_Synaptotagmin-3-5-6-9-10	403..536	CDD:176048	47/112 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1028
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D925064at2759
OrthoFinder	1	1.000	-	-		FOG0000025
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X85
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	6	5.780