Protein Alignment Oli and NEUROG2

DIOPT Version :10

• Sequence 1: NP_523592.1
• Gene: Oli / 35066
• FlyBaseID: FBgn0032651
• Length: 232
• Species: Drosophila melanogaster
• Sequence 2: NP_076924.1
• Gene: NEUROG2 / 63973
• HGNCID: 13805
• Length: 272
• Species: Homo sapiens
• Alignment Length: 245
• Identity: 71/245 - (28%)
• Similarity: 85/245 - (34%)
• Gaps: 77/245 - (31%)

  Fly    27 MLGGQHPAPTASPPQSVPGRRTPLGSVGLGGFYAQGMGMSQQPPTDENKPGPSAPEKPLSPTAAA 91
            :||...||..|..|.|                       |.....:|.:||.|...:   ....|
Human    19 LLGSASPALAALTPLS-----------------------SSADEEEEEEPGASGGAR---RQRGA 57

  Fly    92 IAAIAISGGTTTVAVSSGG---------------------ASGSGSNSGKQKNRQGKTVRLNINA 135
            .|.....||   ||..:.|                     |...|:.:.:...|..||.||..|.
Human    58 EAGQGARGG---VAAGAEGCRPARLLGLVHDCKRRPSRARAVSRGAKTAETVQRIKKTRRLKANN 119

  Fly   136 RERRRMHDLNDALDELRSVIPYAHSPSVRKLSKIATLLLAKNYILMQQNALEELRRLLAYIQSTT 200
            |||.|||:||.|||.||.|:|  ..|...||:||.||..|.|||.    ||.|..||..:.....
Human   120 RERNRMHNLNAALDALREVLP--TFPEDAKLTKIETLRFAHNYIW----ALTETLRLADHCGGGG 178

  Fly   201 GAAPLDLGAF----------PAAAKLQALLQGPH--------NEPPTSSS 232
            |..|   ||.          .|:|.|.:....|.        |.|..|||
Human   179 GGLP---GALFSEAVLLSPGGASAALSSSGDSPSPASTWSCTNSPAPSSS 225

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oli	NP_523592.1	bHLH_TS_bHLHe22_bHLHb5	129..198	CDD:381524	34/68 (50%)
NEUROG2	NP_076924.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	30..69		12/67 (18%)
		bHLH_TS_NGN2_ATOH4	104..172	CDD:381560	37/73 (51%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	197..264		9/29 (31%)