DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Oli and atoh8

DIOPT Version :9

Sequence 1:	NP_001188830.1	Gene:	Oli / 35066	FlyBaseID:	FBgn0032651	Length:	232	Species:	Drosophila melanogaster
Sequence 2:	NP_001073460.2	Gene:	atoh8 / 561606	ZFINID:	ZDB-GENE-061215-7	Length:	266	Species:	Danio rerio

Alignment Length:	90	Identity:	33/90 - (36%)
Similarity:	46/90 - (51%)	Gaps:	18/90 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   105 AVSSGGASGSGSNSGKQKNRQG-------------KTVRLNINARERRRMHDLNDALDELRSVIP 156
            |.|...|.|| ..:...:.|.|             :|.||..|||||.|:|.::.|.:.||..:|
Zfish   140 AASQAPAGGS-ERAESPRKRAGEPSGVVTEIKAIQQTRRLLANARERTRVHTISAAFEALRKQVP 203

  Fly   157 -YAHSPSVRKLSKIATLLLAKNYIL 180
             |::.   :||||:|.|.:|.||||
Zfish   204 CYSYG---QKLSKLAILRIACNYIL 225

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Oli	NP_001188830.1	HLH	134..188	CDD:197674	23/48 (48%)
atoh8	NP_001073460.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	140..164		7/24 (29%)
		Basic motif, degenerate. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00981	175..188		8/12 (67%)
		HLH	176..227	CDD:278439	25/53 (47%)
		Helix-loop-helix motif. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00981	189..227		17/40 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3898
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810