DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Oli and NEUROG1

DIOPT Version :9

Sequence 1:	NP_001188830.1	Gene:	Oli / 35066	FlyBaseID:	FBgn0032651	Length:	232	Species:	Drosophila melanogaster
Sequence 2:	NP_006152.2	Gene:	NEUROG1 / 4762	HGNCID:	7764	Length:	237	Species:	Homo sapiens

Alignment Length:	146	Identity:	46/146 - (31%)
Similarity:	63/146 - (43%)	Gaps:	46/146 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 TDE----------NKPGPSAPEKPLSPTAAAIAAIAISGGTTTVAVSSGGASGSGSNSGKQKNRQ 125
            |||          :..||.||.:..:|..:..:.:                .|:..:..:::.|:
Human    27 TDEEDCARLQQAASASGPPAPARRGAPNISRASEV----------------PGAQDDEQERRRRR 75

  Fly   126 GKT--------------VRLNINARERRRMHDLNDALDELRSVIPYAHSPSVRKLSKIATLLLAK 176
            |:|              .|:..|.|||.|||:||.|||.||||:|  ..|...||:||.||..|.
Human    76 GRTRVRSEALLHSLRRSRRVKANDRERNRMHNLNAALDALRSVLP--SFPDDTKLTKIETLRFAY 138

  Fly   177 NYILMQQNALEELRRL 192
            |||.    ||.|..||
Human   139 NYIW----ALAETLRL 150

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Oli	NP_001188830.1	HLH	134..188	CDD:197674	30/53 (57%)
NEUROG1	NP_006152.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	35..83		9/63 (14%)
		HLH	90..149	CDD:238036	32/64 (50%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	175..209
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145407
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3898
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740