Protein Alignment Oli and Twist1

DIOPT Version :10

• Sequence 1: NP_523592.1
• Gene: Oli / 35066
• FlyBaseID: FBgn0032651
• Length: 232
• Species: Drosophila melanogaster
• Sequence 2: NP_035788.1
• Gene: Twist1 / 22160
• MGIID: 98872
• Length: 206
• Species: Mus musculus
• Alignment Length: 194
• Identity: 57/194 - (29%)
• Similarity: 79/194 - (40%)
• Gaps: 37/194 - (19%)

  Fly    20 PIPPTANMLGGQHPAPTASPPQS--------VPGRRTPLGSVGLGGFYAQGMGMSQQPPTD-ENK 75
            |:.|..:.|......|....|.|        ...||:..||.|.||....|:|...:|.:. :.|
Mouse     9 PVSPADDSLSNSEEEPDRQQPASGKRGARKRRSSRRSAGGSAGPGGATGGGIGGGDEPGSPAQGK 73

  Fly    76 PGPSAPEKPLSPTAAAIAAIAISGGTTTVAVSSGGASGSGSNSG---KQKNRQGKTVRLNINARE 137
            .|..:                 :||........||..|.||:||   .|...:.:|.|:..|.||
Mouse    74 RGKKS-----------------AGGGGGGGAGGGGGGGGGSSSGGGSPQSYEELQTQRVMANVRE 121

  Fly   138 RRRMHDLNDALDELRSVIPYAHSPSVRKLSKIATLLLAKNYI-----LMQQNALEELRRLLAYI 196
            |:|...||:|...||.:||...|.   |||||.||.||..||     ::|.:.|:......:|:
Mouse   122 RQRTQSLNEAFAALRKIIPTLPSD---KLSKIQTLKLAARYIDFLYQVLQSDELDSKMASCSYV 182

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oli	NP_523592.1	bHLH_TS_bHLHe22_bHLHb5	129..198	CDD:381524	28/73 (38%)
Twist1	NP_035788.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..109		28/116 (24%)
		bHLH_TS_TWIST1	102..178	CDD:381418	29/78 (37%)
		Sufficient for transactivation activity	165..195		3/18 (17%)