DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Oli and OLIG1

DIOPT Version :9

Sequence 1:	NP_001188830.1	Gene:	Oli / 35066	FlyBaseID:	FBgn0032651	Length:	232	Species:	Drosophila melanogaster
Sequence 2:	NP_620450.2	Gene:	OLIG1 / 116448	HGNCID:	16983	Length:	271	Species:	Homo sapiens

Alignment Length:	194	Identity:	76/194 - (39%)
Similarity:	97/194 - (50%)	Gaps:	28/194 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 SVPG---RRTPLGSVGLGGFYAQGMGMSQQPPTDENKPGPSAPEKPLSPTAAAIAAIAISGGTTT 103
            :|||   |....|.:.||....:.:|. :|||:..:....|......|.|.|.:...|.......
Human    12 AVPGTMLRPQRPGDLQLGASLYELVGY-RQPPSSSSSSTSSTSSTSSSSTTAPLLPKAAREKPEA 75

  Fly   104 VAVSSGGASGSGSNSG-----KQKNRQGKTVRLNINARERRRMHDLNDALDELRSVI-PY--AHS 160
            .|...|...|||::.|     ..|..|.:.:|..||:|||:||.|||.|:|.||.|| ||  ||.
Human    76 PAEPPGPGPGSGAHPGGSARPDAKEEQQQQLRRKINSRERKRMQDLNLAMDALREVILPYSAAHC 140

  Fly   161 PSV--RKLSKIATLLLAKNYILMQQNALEELRRLLAYIQSTTGAAPLDLGAFPAAAKLQALLQG 222
            ...  ||||||||||||:||||:..::|:||||.|..            ||.|||.:|  ||.|
Human   141 QGAPGRKLSKIATLLLARNYILLLGSSLQELRRALGE------------GAGPAAPRL--LLAG 190

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Oli	NP_001188830.1	HLH	134..188	CDD:197674	36/58 (62%)
OLIG1	NP_620450.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	38..117		22/79 (28%)
OLIG1	NP_620450.2	HLH	107..164	CDD:278439	37/56 (66%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3898
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810