DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Oli and neurod2

DIOPT Version :9

Sequence 1:	NP_001188830.1	Gene:	Oli / 35066	FlyBaseID:	FBgn0032651	Length:	232	Species:	Drosophila melanogaster
Sequence 2:	NP_571157.1	Gene:	neurod2 / 114435	ZFINID:	ZDB-GENE-010608-3	Length:	363	Species:	Danio rerio

Alignment Length:	106	Identity:	45/106 - (42%)
Similarity:	56/106 - (52%)	Gaps:	24/106 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   110 GASGSGSNSGKQ--KNR--------QGKTVRLNINARERRRMHDLNDALDELRSVIP-YAHSPSV 163
            |..|.|....|:  |.|        :.|..|...|||||.||||||.|||.|..|:| |:   ..
Zfish    79 GEEGDGDRPKKRGPKKRKMTPARLERSKVRRQKANARERTRMHDLNSALDNLLKVVPCYS---KT 140

  Fly   164 RKLSKIATLLLAKNYILMQQNALEELRR------LLAYIQS 198
            :|||||.||.||||||.    ||.|:.|      :::|:|:
Zfish   141 QKLSKIETLRLAKNYIW----ALSEILRNGKRPDVVSYVQT 177

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Oli	NP_001188830.1	HLH	134..188	CDD:197674	33/54 (61%)
neurod2	NP_571157.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..116		10/36 (28%)
		Nuclear localization signal. /evidence=ECO:0000255	93..99		2/5 (40%)
		HLH	105..164	CDD:238036	36/65 (55%)
		Neuro_bHLH	166..285	CDD:289310	2/12 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3898
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810