DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7094 and Csnk1a1

DIOPT Version :9

Sequence 1:	NP_609851.2	Gene:	CG7094 / 35065	FlyBaseID:	FBgn0032650	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	XP_006526446.1	Gene:	Csnk1a1 / 93687	MGIID:	1934950	Length:	374	Species:	Mus musculus

Alignment Length:	368	Identity:	199/368 - (54%)
Similarity:	257/368 - (69%)	Gaps:	32/368 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 KLLIGGKYRLVKPIGSGSFGDIYLGLSITDGSEVAIKVEKNDAKYPQLIYEAKVYEQLARCPGFP 84
            :.::||||:||:.|||||||||||.::||:|.|||:|:|...|::|||:||:|:|:.|....|.|
Mouse    10 EFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVGIP 74

  Fly    85 TLLHYGCEKNYNAMVMDLLGPSLEELFNLCKRRFSLKTVLMLTDQLLMRIECVHERGFIHRDIKP 149
            .:..||.||:||.:||||||||||:|||.|.|||::||||||.||::.|||.||.:.||||||||
Mouse    75 HIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRDIKP 139

  Fly   150 DNFLMGLDRHCNK----------------------------LYLIDFGLSKRYKDIESEIHIPYR 186
            ||||||:.|||||                            |:||||||:|:|:|..:..|||||
Mouse   140 DNFLMGIGRHCNKCLESPVGKRKRSMTVSPSQDPSFSGLNQLFLIDFGLAKKYRDNRTRQHIPYR 204

  Fly   187 TDRNLTGTVRYASINAQIGVEQSRRDDMESMSYCLMYFNLGKLPWQGITAANKKQKYEKILEKKT 251
            .|:|||||.|||||||.:|:||||||||||:.|.|||||...|||||:.||.||||||||.|||.
Mouse   205 EDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKM 269

  Fly   252 SVTIAQLCKGFPSEFCLLMTYVRNLGFKEPPDHTYLRQIFRILFRSLNHHYDYIYDWTALQQQKD 316
            |..:..||||||:||.:.:.|.|.|.|:|.||:.||||:||||||:|||.|||.:|||.|:|:..
Mouse   270 STPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQKAA 334

  Fly   317 QICRSREQILESEREEVRKRDGERGCEPQRDKERHKDLELDRL 359
            |...|.    ..:.::.:...|::..:.:.:.:..||.:||.|
Mouse   335 QQAASS----SGQGQQAQTPTGKQTDKTKSNMKGIKDEKLDPL 373

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7094	NP_609851.2	STKc_CK1	26..291	CDD:270918	172/292 (59%)
CG7094	NP_609851.2	SPS1	26..>266	CDD:223589	159/267 (60%)
Csnk1a1	XP_006526446.1	STKc_CK1_alpha	16..309	CDD:271030	172/292 (59%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167849719
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S180
OMA	1	1.010	-	-		QHG54222
OrthoDB	1	1.010	-	-		D1097975at2759
OrthoFinder	1	1.000	-	-		FOG0000297
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100396
Panther	1	1.100	-	-	O	PTHR11909
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.670