DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7094 and Csnk1g3

DIOPT Version :9

Sequence 1:	NP_609851.2	Gene:	CG7094 / 35065	FlyBaseID:	FBgn0032650	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	NP_074046.1	Gene:	Csnk1g3 / 64823	RGDID:	621408	Length:	448	Species:	Rattus norvegicus

Alignment Length:	377	Identity:	162/377 - (42%)
Similarity:	224/377 - (59%)	Gaps:	32/377 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 LLIGGKYRLVKPIGSGSFGDIYLGLSITDGSEVAIKVEKNDAKYPQLIYEAKVYEQLARCPGFPT 85
            |::|..:|:.|.||.|:||::.||.::.....||||:|...::.|||..|.:.|:||....|.|.
  Rat    37 LMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGDGIPQ 101

  Fly    86 LLHYG-CEKNYNAMVMDLLGPSLEELFNLCKRRFSLKTVLMLTDQLLMRIECVHERGFIHRDIKP 149
            :.::| |.| |||||::|||||||:||:||.|.||||||||:..||:.|:|.||.:..|:||:||
  Rat   102 VYYFGPCGK-YNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKP 165

  Fly   150 DNFLMGLDRHCNK----LYLIDFGLSKRYKDIESEIHIPYRTDRNLTGTVRYASINAQIGVEQSR 210
            :|||:|  |..||    :::|||||:|.|.|.|::.|||||..::||||.||.|||..:|.||||
  Rat   166 ENFLIG--RPGNKAQQVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSR 228

  Fly   211 RDDMESMSYCLMYFNLGKLPWQGITAANKKQKYEKILEKKTSVTIAQLCKGFPSEFCLLMTYVRN 275
            |||:|::.:..|||..|.|||||:.|...|::|:||.:.|.:..|..||:.||.|....:.|||.
  Rat   229 RDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEEMATYLRYVRR 293

  Fly   276 LGFKEPPDHTYLRQIFRILFRSLNHHYDYIYDWTALQQQKDQICRSREQILESEREEVRKRDGER 340
            |.|.|.||:.|||::|..||....:.:||.|||...|.........::..|.|.||..:.||
  Rat   294 LDFFEKPDYDYLRKLFTDLFDRKGYMFDYEYDWIGKQLPTPVGAVQQDPALSSNREAHQHRD--- 355

  Fly   341 GCEPQRDKERHKD------------------LELDRLHKTSTQQAKCSNGHL 374
              :.|:.|.:..|                  |..|| |..|.|....:||.|
  Rat   356 --KIQQSKNQSADHRAAWDSQQANPHHLRAHLAADR-HGGSVQVVSSTNGEL 404

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7094	NP_609851.2	STKc_CK1	26..291	CDD:270918	133/269 (49%)
CG7094	NP_609851.2	SPS1	26..>266	CDD:223589	121/244 (50%)
Csnk1g3	NP_074046.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..35
		STKc_CK1_gamma	42..329	CDD:271028	141/289 (49%)
		CK1gamma_C	329..418	CDD:403712	19/82 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	342..375		9/37 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	392..417		5/13 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810