DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7094 and vrk1

DIOPT Version :9

Sequence 1:	NP_609851.2	Gene:	CG7094 / 35065	FlyBaseID:	FBgn0032650	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	NP_998550.1	Gene:	vrk1 / 406694	ZFINID:	ZDB-GENE-040426-2709	Length:	425	Species:	Danio rerio

Alignment Length:	385	Identity:	111/385 - (28%)
Similarity:	176/385 - (45%)	Gaps:	71/385 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 KYRLVKPIGSGSFGDIYLGLSITDGSEVA-----IKVEKND-------------AKYPQLI---Y 69
            |::|...:|.|.||.:||....:.|...|     ||||.:|             |..|.||   .
Zfish    37 KWKLGSAVGQGGFGLLYLANEDSSGPVTADAPYVIKVEPSDNGPLFSELKFYMRAAKPDLIGAWM 101

  Fly    70 EAKVYEQLARCPGFPTLLHYGC---EKN---YNAMVMDLLGPSLEELFNLCKRRFSLKTVLMLTD 128
            ::|..|.|    |.|.  ::|.   |||   |..||||..|..|::||....::||.|.||.|..
Zfish   102 KSKKMEYL----GVPK--YWGSGFHEKNGKRYRFMVMDRFGTDLQKLFEGNGKKFSRKLVLQLGL 160

  Fly   129 QLLMRIECVHERGFIHRDIKPDNFLMGLDRHCNKLYLIDFGLSKRY--KDIESEIHIPYRTD--R 189
            :||..:|.:|:..::|.|||..|.|:.. .:.|:::|:|:||:.||  :.:..|    |:.|  |
Zfish   161 RLLDILEYIHDHEYVHADIKASNLLLSY-TNPNQVFLVDYGLAYRYAPEGVPKE----YKEDPKR 220

  Fly   190 NLTGTVRYASINAQIGVEQSRRDDMESMSYCLMYFNLGKLPWQGITAANKKQK--YEKILEKKTS 252
            ...||:.:.||:|..||..|||.|:|.|.||::.:...:|||:     :|.|.  |.:..:.:..
Zfish   221 CHDGTIEFTSIDAHKGVSPSRRADLEIMGYCMIQWLCSRLPWE-----DKLQDPLYVRDSKLRCR 280

  Fly   253 VTIAQLCK------GFPSEFCLLMTYVRNLGFKEPPDHTYLRQIFRILFRSLNHHYDYIYDWTAL 311
            ..|.:..|      ..|:|....|..|:.||:.:.||:..||.|.:...:|:....|...|:..
Zfish   281 DNIDEFLKSCFASGNIPAEMGKFMQEVKVLGYTDRPDYDKLRGILQQGLKSIGSTDDKKLDFGV- 344

  Fly   312 QQQKDQICRSREQILESEREEVRKRDGERG-------CEPQRDKERHKDLELDRLHKTST 364
                    .:....|.|.:...||:..|:|       ..|.:.:...:..|::...||::
Zfish   345 --------ATNSTSLPSVKTPKRKKAEEKGQSADETDSTPAKKRRAPQKKEVNGAKKTAS 396

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7094	NP_609851.2	STKc_CK1	26..291	CDD:270918	97/303 (32%)
CG7094	NP_609851.2	SPS1	26..>266	CDD:223589	88/278 (32%)
vrk1	NP_998550.1	PKc_like	27..327	CDD:304357	98/305 (32%)
		SPS1	37..>265	CDD:223589	82/243 (34%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	343..425		10/63 (16%)
		GAGA_bind	<373..>424	CDD:283799	4/24 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810