DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7094 and csnk1db

DIOPT Version :9

Sequence 1:	NP_609851.2	Gene:	CG7094 / 35065	FlyBaseID:	FBgn0032650	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	NP_998415.1	Gene:	csnk1db / 406533	ZFINID:	ZDB-GENE-040426-2385	Length:	409	Species:	Danio rerio

Alignment Length:	393	Identity:	189/393 - (48%)
Similarity:	251/393 - (63%)	Gaps:	36/393 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 KLLIGGKYRLVKPIGSGSFGDIYLGLSITDGSEVAIKVEKNDAKYPQLIYEAKVYEQLARCPGFP 84
            :|.:|.:|||.:.||||||||||||..|:.|.|||||:|....|:|||..|:|:|:.:....|.|
Zfish     2 ELRVGNRYRLGRKIGSGSFGDIYLGTDISVGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIP 66

  Fly    85 TLLHYGCEKNYNAMVMDLLGPSLEELFNLCKRRFSLKTVLMLTDQLLMRIECVHERGFIHRDIKP 149
            |:...|.|.:||.|||:|||||||:|||.|.|:|||||||:|.||::.|||.:|.:.|||||:||
Zfish    67 TIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKP 131

  Fly   150 DNFLMGLDRHCNKLYLIDFGLSKRYKDIESEIHIPYRTDRNLTGTVRYASINAQIGVEQSRRDDM 214
            |||||||.:..|.:|:|||||:|:|:|..:..|||||.::|||||.||||||..:|:|||||||:
Zfish   132 DNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDL 196

  Fly   215 ESMSYCLMYFNLGKLPWQGITAANKKQKYEKILEKKTSVTIAQLCKGFPSEFCLLMTYVRNLGFK 279
            ||:.|.|||||||.|||||:.||.|:||||:|.|||.|..|..||||:||||...:.:.|:|.|.
Zfish   197 ESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFD 261

  Fly   280 EPPDHTYLRQIFRILFRSLNHHYDYIYDWTALQ-------QQKDQICRSREQILESEREEV---- 333
            :.||::||||:||.||......|||::||..|:       ::.|:..|.|::.:...|...
Zfish   262 DKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGANRTAEEADRERRERDERMRHSRNPAARGI 326

  Fly   334 -----RKRDGERGC-----------------EPQRDKERHKDLELDRLHKTSTQQAKCSNGHLTN 376
                 |.|..:.|.                 .|....||.:.:.: |||:.:  ....|:..||.
Zfish   327 PAASGRPRPTQDGAPPTPLTPTSHTANTSSPRPVTGMERERKVSM-RLHRGA--PVNVSSSDLTG 388

  Fly   377 RYD 379
            |.|
Zfish   389 RQD 391

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7094	NP_609851.2	STKc_CK1	26..291	CDD:270918	159/264 (60%)
CG7094	NP_609851.2	SPS1	26..>266	CDD:223589	148/239 (62%)
csnk1db	NP_998415.1	STKc_CK1_delta_epsilon	8..282	CDD:271027	163/273 (60%)
		TyrKc	10..273	CDD:197581	158/262 (60%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	300..409		18/95 (19%)
		Autoinhibitory. /evidence=ECO:0000250	317..341		4/23 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54222
OrthoDB	1	1.010	-	-		D1097975at2759
OrthoFinder	1	1.000	-	-		FOG0000297
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100396
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.730