DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7094 and H05L14.1

DIOPT Version :9

Sequence 1:	NP_609851.2	Gene:	CG7094 / 35065	FlyBaseID:	FBgn0032650	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	NP_492198.1	Gene:	H05L14.1 / 172575	WormBaseID:	WBGene00010366	Length:	794	Species:	Caenorhabditis elegans

Alignment Length:	307	Identity:	83/307 - (27%)
Similarity:	146/307 - (47%)	Gaps:	45/307 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 KVRNASLHLEKLLIGGKY--RLVKPIGSGSFGDIYLGLSITDG-------SEVAIKVEKNDAKYP 65
            |:.|.    :.::..|:|  ::|:.:|||.|||:|   .:.|.       :..|:|.|....|..
Worm   446 KIMNP----DDVITNGQYAWKVVRLLGSGGFGDVY---KVFDDKAKGPKKTHYALKTESEGGKKA 503

  Fly    66 QLIYEAKVYEQLA------RCPG-----FPTLLHYGCEKNYNA--MVMDLLGPSLEELFNLCKRR 117
            .|..:.::...:.      :..|     |...:..|..:....  :||.|:||||::    |:|:
Worm   504 MLRLKVEMQVMITISDARKKSKGDVNRHFVDFIDRGKSEELKCKYIVMSLVGPSLDD----CRRK 564

  Fly   118 FSL-----KTVLMLTDQLLMRIECVHERGFIHRDIKPDNFLMGLDRHCNKLYLIDFGLSKRYKDI 177
            |.:     .|..::..|.|..|..:|..|::||||||.||.:|:....:.::::|||:.:.|.|.
Worm   565 FGVNLSNTSTPYIIAIQTLESIRDLHNLGYLHRDIKPANFAVGVGAKESTVFMLDFGIGRSYLDP 629

  Fly   178 ESEIHIPYRTDRNLTGTVRYASINAQIGVEQSRRDDMESMSYCLMYFNLGKLPWQGITAANKKQK 242
            :::.|...|......||:||||....:.|:|.|:||:|...|  |.|::.. |..|::.  |||:
Worm   630 KTKQHRAPRKKVKFLGTLRYASRACMLEVDQGRKDDLECWIY--MVFDIFD-PKNGVSW--KKQR 689

  Fly   243 YE-KILEKKTSVTIAQLCKGF-PSEFCLLMTYVRNLGFKEPPDHTYL 287
            .. ||.|.|......:....: |.....::.|:.:|.|:..|::..|
Worm   690 DRVKIREAKQLFFDGKAQYDYAPISLRPIIIYINSLQFQTTPEYANL 736

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7094	NP_609851.2	STKc_CK1	26..291	CDD:270918	80/291 (27%)
CG7094	NP_609851.2	SPS1	26..>266	CDD:223589	75/268 (28%)
H05L14.1	NP_492198.1	PKc_like	137..385	CDD:304357
		SPS1	194..>369	CDD:223589
		PKc_like	461..736	CDD:304357	78/286 (27%)
		SPS1	461..>651	CDD:223589	53/196 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810