DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7094 and Ttbk1

DIOPT Version :9

Sequence 1:	NP_609851.2	Gene:	CG7094 / 35065	FlyBaseID:	FBgn0032650	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	NP_001156336.1	Gene:	Ttbk1 / 106763	MGIID:	2147036	Length:	1308	Species:	Mus musculus

Alignment Length:	323	Identity:	106/323 - (32%)
Similarity:	165/323 - (51%)	Gaps:	35/323 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 AKQEATN--GKVRNASLHLEKLLIGGKYRLVKPIGSGSFGDIYLGLSITDGSEVAIKVEKNDAKY 64
            |.::.||  |....|.:.....::..:::::|.||.|.||:||..:.:.....||:|||  .|:.
Mouse     7 ALKDETNMSGGGEQADILPANYVVKDRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVE--SAQQ 69

  Fly    65 PQLIYEAKVYEQLARCPGFPTLLHY-GCEKN--YNAMVMDLLGPSLEELFNLCKRR------FSL 120
            |:.:.:.:| ..|.:..|...:..: ||.:|  :|.:||.|.|.:|.:|     ||      |:|
Mouse    70 PKQVLKMEV-AVLKKLQGKDHVCRFIGCGRNEKFNYVVMQLQGRNLADL-----RRSQPRGTFTL 128

  Fly   121 KTVLMLTDQLLMRIECVHERGFIHRDIKPDNFLMG-LDRHCNKLYLIDFGLSKRYKDIESEIHIP 184
            .|.|.|..|:|..||.:|..||:||||||.||.|| |.....|.|::||||:::|.:...::. |
Mouse   129 STTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNTTGDVR-P 192

  Fly   185 YRTDRNLTGTVRYASINAQIGVEQSRRDDMESMSYCLMYFNLGKLPWQGITAANK----KQKYEK 245
            .|......|||||||:||....|..|.||:.|:.|.|:.|.:|:|||:.|....:    |:|||.
Mouse   193 PRNVAGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGMIKEKYEH 257

  Fly   246 ILEKKTSVTIAQLCKGFPSEFCLLMTYVRNLGFKEPPDHTYLRQIFRILFRSLNHHYDYIYDW 308
                      ..|.|..||||.|.:.::.:|.:...||:..:..:|....:......:..:||
Mouse   258 ----------RMLLKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKERGIAENEAFDW 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7094	NP_609851.2	STKc_CK1	26..291	CDD:270918	98/278 (35%)
CG7094	NP_609851.2	SPS1	26..>266	CDD:223589	92/253 (36%)
Ttbk1	NP_001156336.1	STKc_TTBK1	33..294	CDD:271032	98/279 (35%)
		PHA03307	324..>683	CDD:223039
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	364..397
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	418..448
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	474..671
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	720..899
		PHA03307	963..>1305	CDD:223039
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	985..1085
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1097..1308
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810