Protein Alignment CG15144 and CFAP91

DIOPT Version :10

• Sequence 1: NP_609849.2
• Gene: CG15144 / 35063
• FlyBaseID: FBgn0032648
• Length: 1038
• Species: Drosophila melanogaster
• Sequence 2: NP_203528.3
• Gene: CFAP91 / 89876
• HGNCID: 24010
• Length: 767
• Species: Homo sapiens
• Alignment Length: 695
• Identity: 160/695 - (23%)
• Similarity: 290/695 - (41%)
• Gaps: 166/695 - (23%)

  Fly   150 FNEPGI-FFLQKPHSDFTTQEVKLNAKPIRKELKNKCDFFP----KYVDNRPFKDEATQTLYRES 209
            |..|.: ||.|.|   |........|:|..         ||    |::.........|||.||::
Human   146 FERPFLPFFQQMP---FNVVYAVSKAEPYT---------FPPTSTKHLSIPSKSTVGTQTDYRDA 198

  Fly   210 SAQTLAFLPE-ILNKDKSETFELYTLAKLLPG-DKPPGLHEVEFLERAR--RRWKFS-KALKDNF 269
            ..||..:..| ::.:|...  ||.|||.|..| ..|.|..|||.:||||  |.|:.| .||.|.
Human   199 DVQTDPYSAEYVVCQDSIP--ELLTLATLTWGRGLPAGQAEVEMIERAREKRAWEASLPALSDT- 260

  Fly   270 KRLLCEAREVSIKTQY---KEILEAFEWEQWIQREEDIQQCQMMRLEIVIKMFDKREKEMHNAS- 330
                         :|:   ::::...|.::|..||::|::.|.:|||::.::..|||:..:..:
Human   261 -------------SQFEKRRKMMNEMERKEWAFREQEIEKLQEIRLEVLKELLRKREENQNEVNM 312

  Fly   331 ---KARIEKSVQQIEKRRQDGLRKNEIEYQRGM--RRNNIQLAKTARKWEKQSPMQALGSPCSEF 390
               .||..| :|:.::.:...:::..:...|.:  :|.||:     .|.|:::.::......|:.
Human   313 KHLNARWSK-LQEGKEAKMAKIQRTHVSTIRKLVGKRKNIE-----GKLERRNIIKDYSDYASQV 371

  Fly   391 YGPLIRYGVDPARRCFESNTGR----KAFDMR----IDELEK----RVNMRNVQCPFSKLKEWSK 443
            ||||.|.|      ||..|...    |.:.:.    :.|||.    .|....::.|        |
Human   372 YGPLSRLG------CFPDNNSEDFVVKNYYLNTYEGLVELESCLPDFVTQPQIRAP--------K 422

  Fly   444 PKEYDRE---YERNFCNDGNLQRLYESLKTLRTQADMAKEPPQCLK----TRLRIEHRTSSSSST 501
            ||....:   .:|....|..|..::::|...:.:....|:||:.|:    .:.|:...|...:|.
Human   423 PKVITTKAGFLKRAARLDYELAEVHKALLDKKNKVLEVKKPPRFLQRNPIPQPRLPTPTLEMTSN 487

  Fly   502 DS------------------YRNYNWQARKSRFVELSEGLRSTKTTIKKMAPQRAEKLVRGS--- 545
            :.                  .:|..::.::.| :||.:.||:..      |.|..||||:.:
Human   488 EEEEMEMAVIYLQKLLRGRVVQNMMFEGKEKR-LELIQELRTCH------ALQEDEKLVKKAEKQ 545

  Fly   546 ---VIRRE---------YLETLICSYEGSYVGTMMQFLADEMQRLKEQRKLHFFCILAQKERWRR 598
               .::|:         .:|..:...||..:..|..||:.|:.||:|:|::|.|.:||:::|..|
Human   546 VTLALQRQRNLHEHKVSLVENHLAGLEGRALADMFDFLSKELVRLQEERRIHAFVMLAERQRRVR 610

  Fly   599 EAAEAGLRQKENCMRMLYEEMFQFTNSVHSEIAEKYADTILTTDVGNMVEEETAETITELAKQID 663
            ||.|:|.||.|.......:|:|:....||......|.:.|:.....|..||:....|.::|::|:
Human   611 EAEESGRRQVEKQRLREEDEIFKEVVKVHHSTISSYLEDIILNTEANTAEEQARAEIEKMAEKIN 675

  Fly   664 ADIERWLESFKLIQNPLNFTPLRLMLQDMVSPDMGATLRRYETSLIVQYIVEDVIFYNLWQE--- 725
             ||...:||.:..          |..:::|:            .|:..:::.:|..|.:.::
Human   676 -DIAYEMESRRTY----------LQSEEIVA------------ELVYSFLIPEVQKYFVKEKVRN 717

  Fly   726 ------LEPFDIASTLTSDLIDRLIDNDLFLFSSDSESDSGHGAS 764
                  |....|..:.|..::.:.:        ::.|.|....|:
Human   718 AQRKHILAAHQIIHSYTESMVQKKL--------TEGEQDEASNAA 754

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15144	NP_609849.2	CFAP91	202..362	CDD:464290	49/173 (28%)
CFAP91	NP_203528.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..29
		CFAP91	191..343	CDD:464290	48/168 (29%)
		Smc	<514..>692	CDD:440809	53/195 (27%)