Protein Alignment CG15143 and CFAP91

DIOPT Version :10

• Sequence 1: NP_609848.1
• Gene: CG15143 / 35062
• FlyBaseID: FBgn0032647
• Length: 1152
• Species: Drosophila melanogaster
• Sequence 2: NP_203528.3
• Gene: CFAP91 / 89876
• HGNCID: 24010
• Length: 767
• Species: Homo sapiens
• Alignment Length: 661
• Identity: 135/661 - (20%)
• Similarity: 263/661 - (39%)
• Gaps: 138/661 - (20%)

  Fly    65 GENDPAQRNVGKLPRTDSECQ-------------------FKAPGYRFLTEQDTTVNTHEVKMSP 110
            |..:..:..:.:|..||:..|                   |:.|...|..:....|.....|..|
Human   106 GHKEKHREALRQLTTTDASFQMPKEVYEDPEVTGKNRYKYFERPFLPFFQQMPFNVVYAVSKAEP 170

  Fly   111 RVVTKKDLRHKCDFFAKNKDARPFKNKI-TQTLYRESSAQTMAYLPEIFEANSVETLELFSLPSI 174
            ........:|.         :.|.|:.: |||.||::..||..|..|......       |:|.:
Human   171 YTFPPTSTKHL---------SIPSKSTVGTQTDYRDADVQTDPYSAEYVVCQD-------SIPEL 219

  Fly   175 FPVAN-------RPGLHEVEILERARKRWAFSDALKIHFKNLLQDARKVAIKTELKEILEAIEWE 232
            ..:|.       ..|..|||::||||::.|:..:|.     .|.|..:.   .:.::::..:|.:
Human   220 LTLATLTWGRGLPAGQAEVEMIERAREKRAWEASLP-----ALSDTSQF---EKRRKMMNEMERK 276

  Fly   233 QWIQREEDIQECQMMRLQIVIKMFDKREKEMHTASKTRIETACERIEKRRQAGLRKNEIEFQRGM 297
            :|..||::|::.|.:||:::.::..|||:..:..:...:.....::::.::|.:.|.:......:
Human   277 EWAFREQEIEKLQEIRLEVLKELLRKREENQNEVNMKHLNARWSKLQEGKEAKMAKIQRTHVSTI 341

  Fly   298 RRMEFQLTKNPRRWEKQSPMYALGSPSSEFYAPLLRYGVDPAR--RNFVSK-------------- 346
            |::..:......:.|:::.:......:|:.|.||.|.|..|..  .:||.|
Human   342 RKLVGKRKNIEGKLERRNIIKDYSDYASQVYGPLSRLGCFPDNNSEDFVVKNYYLNTYEGLVELE 406

  Fly   347 --------------------TAQKAF-------DMRIDDLEKRINNTDFKCPFRKLKDWSKPKKY 384
                                |.:..|       |..:.::.|.:  .|.|   .|:.:..||.::
Human   407 SCLPDFVTQPQIRAPKPKVITTKAGFLKRAARLDYELAEVHKAL--LDKK---NKVLEVKKPPRF 466

  Fly   385 DKEYERNFCKEDNLQKLFESLKGLRTQANAEREEPKCLVRRRKPELGRAASQITLAYLTDLYE-- 447
               .:||...:..|     ....|...:|.|.|....::..:|...||....:       ::|
Human   467 ---LQRNPIPQPRL-----PTPTLEMTSNEEEEMEMAVIYLQKLLRGRVVQNM-------MFEGK 516

  Fly   448 --RSDSDEEYRKSRAYGSFSPHAKPGTNKVSETTLSHLKNDRKREEMEHMLNIYEGTYVGW---- 506
              |.:..:|.|...|........|....:|:      |...|:|...||.:::.|....|.
Human   517 EKRLELIQELRTCHALQEDEKLVKKAEKQVT------LALQRQRNLHEHKVSLVENHLAGLEGRA 575

  Fly   507 ---VMQFLSEEMTRLSELRRLHFFSIMAQKERWRREAAEAGLRQKENELRLLYEELFQHCNVVNN 568
               :..|||:|:.||.|.||:|.|.::|:::|..|||.|:|.||.|.:.....:|:|:....|::
Human   576 LADMFDFLSKELVRLQEERRIHAFVMLAERQRRVREAEESGRRQVEKQRLREEDEIFKEVVKVHH 640

  Fly   569 EISNKYFANILSSDMYGMADGLAGETVSELAKKIDADILRWLESFKLIQNPLTYVPLRIMLNDMI 633
            ...:.|..:|:.:.....|:..|...:.::|:||: ||...:||.:      ||:....::.:::
Human   641 STISSYLEDIILNTEANTAEEQARAEIEKMAEKIN-DIAYEMESRR------TYLQSEEIVAELV 698

  Fly   634 SPNMNNILQRY 644
            ...:...:|:|
Human   699 YSFLIPEVQKY 709

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15143	NP_609848.1	CFAP91	139..299	CDD:464290	37/166 (22%)
CFAP91	NP_203528.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..29
		CFAP91	191..343	CDD:464290	37/166 (22%)
		Smc	<514..>692	CDD:440809	51/190 (27%)