DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Dhc36C and DNAH9

DIOPT Version :9

Sequence 1:	NP_001369131.1	Gene:	Dhc36C / 35061	FlyBaseID:	FBgn0013810	Length:	4065	Species:	Drosophila melanogaster
Sequence 2:	XP_011522005.1	Gene:	DNAH9 / 1770	HGNCID:	2953	Length:	4501	Species:	Homo sapiens

Alignment Length:	4299	Identity:	1315/4299 - (30%)
Similarity:	2077/4299 - (48%)	Gaps:	644/4299 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 KMLYTRPKPDVLQSILQSKANPEYKSRRLWYELNMPECASSLLDGKMKSDLPDNIL--------- 85
            :|:|::.    :|...:...:|.:|        |||..|..|   :...:|...|.
Human   582 RMIYSQH----VQEEAELGFSPVHK--------NMPTVAGGL---RWAQELRQRIQGPFSNFGRI 631

  Fly    86 ---CAKKQQKKR-QKKRESGVAKANYMTMRLEREHFRRKLVELILHMDDDQDPELAAQCAVPFP- 145
               |.:..:.|| |:|.|.       |...||:...|       |:.|..:.....:|..:..|
Human   632 THPCMESAEGKRMQQKYED-------MLSLLEKYETR-------LYEDWCRTVSEKSQYNLSQPL 682

  Fly   146 ---DQEEREILRYYYYIKHGIDTIHVSPLSKKILKRITDLVP----------------------- 184
               |.|.:||            ||:.:|....:||.::.|.|
Human   683 LKRDPETKEI------------TINFNPQLISVLKEMSYLEPREMKHMPETAAAMFSSRDFYRQL 735

  Fly   185 ----PLLYKWQTALNENIAEVR-----------------------------ADYVFAMKKAVVDF 216
                .|:..|...:.:.:.||.                             .|||..:..::
Human   736 VANLELMANWYNKVMKTLLEVEFPLVEEELQNIDLRLRAAEETLNWKTEGICDYVTEITSSI--- 797

  Fly   217 VLRHTVLDRL--TKEGVGGKYDTAERREVQSMTNFWRYRYDENRNVLMKTLFCIHRSVASILELW 279
               |.:..|:  ||:.|         .|:|::...|       ...:.||......|:.|:.:..
Human   798 ---HDLEQRIQKTKDNV---------EEIQNIMKTW-------VTPIFKTKDGKRESLLSLDDRH 843

  Fly   280 SMKYKDKSLIDSKEL---AKVESPFSLF----------TFVYLCGSHIDNGKTLLEESWYGEIHS 331
            ....|..:||....|   |.|:....||          |:|    :.|||
Human   844 DRMEKYYNLIKESGLKIHALVQENLGLFSADPTSNIWKTYV----NSIDN--------------- 889

  Fly   332 SLLKASKRGQLPDIRRFTLVKRFFNCVAALMTQQLEDI-CIRSLKEYADFICDYGHSNPGFEISV 395
                             .|:..||..:...:...||:. |...|             .|.||..:
Human   890 -----------------LLLNGFFLAIECSLKYLLENTECKAGL-------------TPIFEAQL 924

  Fly   396 MLADEDTIQFNPSF-SKVQSELLRVIDSIMLSIQMLPRIESKLYTDLIVSKKIFLTPTVPESIVQ 459
            .||..:.: |.||. |.|:.....:::.::.||..:|.:                   ||.
Human   925 SLAIPELV-FYPSLESGVKGGFCDIVEGLITSIFRIPSL-------------------VPR---- 965

  Fly   460 ETKNRICAMLEEQRIGPELRLQDFDPFIDLIN--GSDAERVGNFM----ESDATFEQYADMVYEY 518
                     |..|...|..:: |.|...||.|  .:..|||...|    ...:||.||:   |.|
Human   966 ---------LSPQNGSPHYQV-DLDGIPDLANMRRTLMERVQRMMGLCCGYQSTFSQYS---YLY 1017

  Fly   519 KEKEDRI------------AKEVWAVIRMGF---------YEFHRDKFITHLESLCR-------- 554
            .|....:            .:|:...:..|.         ::...|.:.|..|.:||
Human  1018 VEDRKEVLGQFLLYGHILTPEEIEDHVEDGIPENPPLLSQFKVQIDSYETLYEEVCRLEPIKVFD 1082

  Fly   555 -QLQLDLLARMVTDQQARITRLGKEYDAIAKKALTVPKDTAELMQLKAYVVHAEENLVPEMEARL 618
             .:::|     :...:|.:..:.|.:..:.|:.| |...|..|..|.|::..:|..|:.::|
Human  1083 GWMKID-----IRPFKASLLNIIKRWSLLFKQHL-VDHVTHSLANLDAFIKKSESGLLKKVE--- 1138

  Fly   619 KVNMSEILWLMDHTLYSPLEIKNNSNSFQ-----------WYLKLP-SIFEQHRAI--------- 662
            |.:...::.:|.|.:.......|....|:           :..:|| ::|:|...:
Human  1139 KGDFQGLVEIMGHLMAVKERQSNTDEMFEPLKQTIELLKTYEQELPETVFKQLEELPEKWNNIKK 1203

  Fly   663 ----IAEKVIEYQ----ELLKKRIELFRRELQNYYEQVQTYDTWGDIKQLSRYKKRA-------- 711
                :.::|...|    .||::|...|..|.|.::||               :.|.|
Human  1204 VAITVKQQVAPLQANEVTLLRQRCTAFDAEQQQFWEQ---------------FHKEAPFRFDSIH 1253

  Fly   712 --GVLDQR--LVQAME-TIDQINEEETSYGWDLSQYPMRKKAHDQLKPYKTLFDAGQDFMDKWDL 771
              .:||.|  .:|.|| |:..|:|..:.:..::..|...::...::...|.|:|...........
Human  1254 PHQMLDARHIEIQQMESTMASISESASLFEVNVPDYKQLRQCRKEVCQLKELWDTIGMVTSSIHA 1318

  Fly   772 WMHSQVGSFDPDEIDGDVSNFYRIIQKLDKQM-------GDHPITMQLIQDVKAQIEAFREHMPI 829
            |..:...:.:.:.::.:...|.|.|:.|||::       |........:..::|..|
Human  1319 WETTPWRNINVEAMELECKQFARHIRNLDKEVRAWDAFTGLESTVWNTLSSLRAVAE-------- 1375

  Fly   830 INTLGNPGMKARHWELVSEIIGFPIKVSPELTLEKIIEYQLDEYVPKFEAISESATKENNLERAM 894
               |.||.::.|||..:.:..|....:..:.||..:::.||..|..:...|.:.|.||..:|:.:
Human  1376 ---LQNPAIRERHWRQLMQATGVSFTMDQDTTLAHLLQLQLHHYEDEVRGIVDKAAKEMGMEKTL 1437

  Fly   895 AKMVNEWEGVEFSISPYRDSGTFKLAAVDDIQILLDDQIIKTQTMKSSPYIKPFEADIIKWEAKL 959
            .::...|.|:||...|:..:....|.:.:|:..:|:|..::.|.:..|.|:..|..::..|:.||
Human  1438 KELQTTWAGMEFQYEPHPRTNVPLLCSDEDLIEVLEDNQVQLQNLVMSKYVAFFLEEVSGWQKKL 1502

  Fly   960 MLLQEILDEWLRVQATWMYLEPIFS-SPDIQQQMPEEGRRFSAVDKIWKELMKQVSQDPKVMVVV 1023
            ..:..::..|..||.||.:||.||: |.||:.|:|::.:||..:|..:|||.....:.|.|:...
Human  1503 STVDAVISIWFEVQRTWTHLESIFTGSEDIRAQLPQDSKRFEGIDIDFKELAYDAQKIPNVVQTT 1567

  Fly  1024 QIDKMNDKLKKAYSLLEVIQKGLNAYLEKKRLYFPRFFFLSNDELLEILSETKDPTRVQIHLKKC 1088
            ....:.:||:.....|.:.:|.|..||:.|||.||||:|||:.:||:|||....|.:||.||.|.
Human  1568 NKPGLYEKLEDIQGRLCLCEKALAEYLDTKRLAFPRFYFLSSSDLLDILSNGTAPQQVQRHLSKL 1632

  Fly  1089 FEGIATLNFTEELDVT--------AMRSSEREEVTLVDVISTSKARGQVEKWLLELEIDMKKSVH 1145
            |:.:|.:.|  :||.:        .|.|.|.|.|...:....|   ||||.||..:...||.:|.
Human  1633 FDNMAKMRF--QLDASGEPTKTSLGMYSKEEEYVAFSEPCDCS---GQVEIWLNHVLGHMKATVR 1692

  Fly  1146 HKVSEAFYSYLKMLRHVWVLTWPGQCVQSISLTYWTLEITECF-ESEEPKENLAK-YLQKCVLQI 1208
            |:::|...:|.:..|..|:...|.|...:.:..:||.|:...| ..||..|:..| |.:|.|.|:
Human  1693 HEMTEGVTAYEEKPREQWLFDHPAQVALTCTQIWWTTEVGMAFARLEEGYESAMKDYYKKQVAQL 1757

  Fly  1209 NKIVDLVRGDLNTQNRITLGALVVLDVHARDVLAEIVANQVEDLQDFQWLCQLRYYWED------ 1267
            ..::.::.|.|:..:|..:..:..:|||||||:|:::|.:|::.|.|.||.|||:.|:|
Human  1758 KTLITMLIGQLSKGDRQKIMTICTIDVHARDVVAKMIAQKVDNAQAFLWLSQLRHRWDDEVKHCF 1822

  Fly  1268 -NNLDTRMINCSLPYGYEYLGNTPRLVVTPLTDRCYRTLFAALNLHLGGAPEGPAGTGKTETTKD 1331
             |..|.:.:     |.|||||||||||:||||||||.||..:|:|.:.|||.|||||||||||||
Human  1823 ANICDAQFL-----YSYEYLGNTPRLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTGKTETTKD 1882

  Fly  1332 LAKAVAKQCVVFNCSDGLDYLALGKFFKGLASCGAWSCFDEFNRIDLEVLSVVAQQILTIQRGIN 1396
            |.:|:.....|||||:.:||.:.|..:||||..|||.||||||||.:|||||||.|:.:||..|.
Human  1883 LGRALGILVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVVAVQVKSIQDAIR 1947

  Fly  1397 SGSPTLVFEGTTLTLDPTCAVFITMNPGYAGRSELPDNLKALFRSVAMMVPDYALISEIELYSYG 1461
            .......|.|..::|:|:..:|||||||||||:|||:|||:|||..||:|||:.||.||.|.:.|
Human  1948 DKKQWFSFLGEEISLNPSVGIFITMNPGYAGRTELPENLKSLFRPCAMVVPDFELICEIMLVAEG 2012

  Fly  1462 FLTAKPLSVKIVATYRLCSEQLSTQCHYDYGMRAVKSVLKAAGALKLRYRDENEDILVLRSIKDV 1526
            |:.|:.|:.|.:..|:||.|.||.|.|||:|:||:||||..||:||....|..||.:::||::|.
Human  2013 FIEAQSLARKFITLYQLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPDRPEDQVLMRSLRDF 2077

  Fly  1527 NLPKFLNQDIPLFQGITSDLFPGTVLPEADYVLFNKCTQMACERQNKQCTPFVLEKVQQLYEMIV 1591
            |:||.:..|:|:|.|:..||||...:|......|....:.|......|.....:.||.||.|::.
Human  2078 NIPKIVTDDMPIFMGLIGDLFPALDVPRRRDPNFEALVRKAIVDLKLQAEDNFVLKVVQLEELLA 2142

  Fly  1592 VRHGLMLVGYPFGGKTTTYRVLAEALECMEKTDGSENKAIYTVINPKAITMGQLYGQFDAVSHEW 1656
            |||.:.:||....||:...|.|.:..:.|::      :.::|.:||||:|..:|:|..:..:.||
Human  2143 VRHSVFVVGGAGTGKSQVLRSLHKTYQIMKR------RPVWTDLNPKAVTNDELFGIINPATGEW 2201

  Fly  1657 SDGILAVNYRIFA--ISDSPDRKWLIFDGPVDAIWIENMNTVLDDNKKLCLMSGEIIQLSNTTNL 1719
            .||:.:...|..|  ..|.|  ||::.||.:|.:|||::|||:||||.|.|.|.|.|.|:.|..|
Human  2202 KDGLFSSIMRELANITHDGP--KWILLDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNPTMKL 2264

  Fly  1720 VFEPMDLEVASPATVSRCGMIYLEPSSLGWEPLVASW--KNTLPAAFHTVSKQLISMLISRFCPI 1782
            :||...|..|:||||||.|::|:.|:.|||.|.|:||  |..:     ...:..:::|..::.|.
Human  2265 LFEISHLRTATPATVSRAGILYINPADLGWNPPVSSWIEKREI-----QTERANLTILFDKYLPT 2324

  Fly  1783 LLFILRKSLKEIAPTSDANLMVSLMNFFECFID------DFRDEKYVANVSDLDFRAQTEGIFLF 1841
            .|..||...|:|.|..:.:::..:.:..||.:.      |...|.|             |..|:|
Human  2325 CLDTLRTRFKKIIPIPEQSMVQMVCHLLECLLTTEDIPADCPKEIY-------------EHYFVF 2376

  Fly  1842 SCIWSLGGSLDADSREKFNIIFRALMEKTFPQSLYDTYGVPEDLYVESLAKPFIFPIPKQGSVFD 1906
            :.||:.||::..|..    :.:||...|.:                  |.:......|.||::||
Human  2377 AAIWAFGGAMVQDQL----VDYRAEFSKWW------------------LTEFKTVKFPSQGTIFD 2419

  Fly  1907 YRYIKEGKGKWKPWQDDVNSAPPIPRDIPVNQIIIQTNESVRIGAVLDLLNRHGKPIMLVGPTGT 1971
            | ||.....|::||...|......| ::|:...::.|:|::|:...::.|....:|:||||..||
Human  2420 Y-YIDPETKKFEPWSKLVPQFEFDP-EMPLQACLVHTSETIRVCYFMERLMARQRPVMLVGTAGT 2482

  Fly  1972 GKSVYVIDYMLKKMDLSFYKPLLISFSAQTSANQTQDIIMSKLDKRRKGVFGPPLNSRFVIFVDD 2036
            |||| ::...|..:|...|....:.|:..|::...|.::...|:|:....:|||.|.:.:.|:||
Human  2483 GKSV-LVGAKLASLDPEAYLVKNVPFNYYTTSAMLQAVLEKPLEKKAGRNYGPPGNKKLIYFIDD 2546

  Fly  2037 VSMPLKENYGAQPPIELLRMMLDHMMWYDRKNIVPMKLIDLQMIVAMGPPSTGNTVTPRFQRFFN 2101
            ::||..:.||...|..::|..||:..||||..:...::.::|.:..|.|.:...|:.||.||.|:
Human  2547 MNMPEVDAYGTVQPHTIIRQHLDYGHWYDRSKLSLKEITNVQYVSCMNPTAGSFTINPRLQRHFS 2611

  Fly  2102 VISIDDFNNDILNTIFSKIVLWHLDTRGFSKEFDPCIDEIVGATLTIYNDAKLNLLPTPAKSHYL 2166
            |..:.....|.|::|:|.|:..||....|.......|..::...|..:.......|||..|.||:
Human  2612 VFVLSFPGADALSSIYSIILTQHLKLGNFPASLQKSIPPLIDLALAFHQKIATTFLPTGIKFHYI 2676

  Fly  2167 FNLRDFSRVIQGVLLSVPEATEDVNSMRRLWVHEVLRVYGDRLVEDADRSWLFENICSTV-KSCF 2230
            ||||||:.:.||:|.|..|..:....:.||::||..|||.|::||:.|.. ||:.|.:.| |..|
Human  2677 FNLRDFANIFQGILFSSVECVKSTWDLIRLYLHESNRVYRDKMVEEKDFD-LFDKIQTEVLKKTF 2740

  Fly  2231 N--TDPSRLFGRLVEKDKSLQESDFRQLIYCDFTNPKADTKNYVEVQDLEEL-RRVVEAYLVEYN 2292
            :  .||       ||:.:|..       :||.|.|...:.| |:.||..|.| :.:|||  :|.:
Human  2741 DDIEDP-------VEQTQSPN-------LYCHFANGIGEPK-YMPVQSWELLTQTLVEA--LENH 2788

  Fly  2293 NMSKKPMNLVLFRFAIEHLSRICRIIKQPRSHALLIGVGGSGRQSLTRLASHICDYELFQVEITR 2357
            |.....|:||||..|:.|:..|.||::.||.:|||:||||||:|||||||:.|...::||:.:.:
Human  2789 NEVNTVMDLVLFEDAMRHVCHINRILESPRGNALLVGVGGSGKQSLTRLAAFISSMDVFQITLRK 2853

  Fly  2358 LYGPYEYHEDIKAILRKIGASEMHGVFLFTDVQIKDESFLEDISNLLNSGEVPNLFTNEEKIEVQ 2422
            .|...::..|:.::..|.|...::.|||.||.|:.||.||..|::||.|||:|:|::::   ||:
Human  2854 GYQIQDFKMDLASLCLKAGVKNLNTVFLMTDAQVADERFLVLINDLLASGEIPDLYSDD---EVE 2915

  Fly  2423 EKMAQIDKQRDKAVQTDG---SPVALFNFFVTTCKDQLHIVLAMSPIGDALRNRIRKFPSIVNCC 2484
            ..::.:..:    |::.|   :....:.||:...:.||.:.|..||:|:.||.|.||||:||||.
Human  2916 NIISNVRNE----VKSQGLVDNRENCWKFFIDRIRRQLKVTLCFSPVGNKLRVRSRKFPAIVNCT 2976

  Fly  2485 TIDWFQSWPEDALLAVSTRFLASEDLTALERRTAIDMCMEF-HTSTQELSAKFFSRLHRYNYVTP 2548
            .|.||..||:.||.:||.|||.:.:......:.:|...|.| |||..:.|..:.|...||||.||
Human  2977 AIHWFHEWPQQALESVSLRFLQNTEGIEPTVKQSISKFMAFVHTSVNQTSQSYLSNEQRYNYTTP 3041

  Fly  2549 TSYLELIQTFKALLSQKRNNITNNRNRYLTGISQLDIAAQQVAVMQEQLIALEPKLKEASE---- 2609
            .|:||.|:.:::||.:.|..:.....|...|:.:|...:.||..::.:|.|.|.:||:.:|
Human  3042 KSFLEFIRLYQSLLHRHRKELKCKTERLENGLLKLHSTSAQVDDLKAKLAAQEVELKQKNEDADK 3106

  Fly  2610 ---IVAEQVAKVTADSKLAEEQREIVKLDESAAKEQAAVAQEIKD---ECDAKLGEALPILESAL 2668
               :|..:..||:.:..:|:|:.:.|          |.:..|:|.   :|:..|.:|.|.|.:|.
Human  3107 LIQVVGVETDKVSREKAMADEEEQKV----------AVIMLEVKQKQKDCEEDLAKAEPALTAAQ 3161

  Fly  2669 AALNTLTTADIAVVKTMKSPPIGVRIVMEAVCILKDVKPDKVPNPSGLGTVEDYWGPSKRVLSDM 2733
            ||||||...::..:|:..|||:.|..|..||.:|.        .|.|....:..|..:|..::.:
Human  3162 AALNTLNKTNLTELKSFGSPPLAVSNVSAAVMVLM--------APRGRVPKDRSWKAAKVTMAKV 3218

  Fly  2734 K-FLDSLLNFDKDNIPVEVMKKLAQRILSNEAFDPDKIKSASTACEGLCRWVIALTKYDVVAKIV 2797
            . |||||:||:|:||....:|.: :..|.:..|:|:.:.:.|.|..|||.|||.:.::..|...|
Human  3219 DGFLDSLINFNKENIHENCLKAI-RPYLQDPEFNPEFVATKSYAAAGLCSWVINIVRFYEVFCDV 3282

  Fly  2798 APKKLALAEAEATYNAAMKTLNEKLAMLAKVEANLAAI----QKILDEQLRQYGILLAEHEACTK 2858
            .||:.||.:|.|...||.:.|....|.:|.:..|||.:    :|...::|:    ...|.|....
Human  3283 EPKRQALNKATADLTAAQEKLAAIKAKIAHLNENLAKLTARFEKATADKLK----CQQEAEVTAV 3343

  Fly  2859 KLQRAQELISGLGGERTRWSETAKMLQASFKSVTGDVLISSGVVSYLGPFTIDFRVDQI-RKW-- 2920
            .:..|..|:.||..|..||::..:..:...:::.||:|:.:..:||||.||..:|...: |.|
Human  3344 TISLANRLVGGLASENVRWADAVQNFKQQERTLCGDILLITAFISYLGFFTKKYRQSLLDRTWRP 3408

  Fly  2921 VTKCLNFGVTCTADFQLAVVLGEPVEIRFWNICGLPTDAFSIESAIMMKNARRWPLMIDPQGQAN 2985
            ....|...:..|.......:|.:..::..|...|||.|..|:|:|.::.|..|||||:|||.|..
Human  3409 YLSQLKTPIPVTPALDPLRMLMDDADVAAWQNEGLPADRMSVENATILINCERWPLMVDPQLQGI 3473

  Fly  2986 KWIKNYEKNNKLCVIRLNQADYTRVMENAIQFGLPVLLENIGEELDPVLESVLQKTLFKQGGALC 3050
            ||||| :....|.|.::.|..|.:::|.|::.|..||:||:.|.:||||..:|.:.:.|:|  ..
Human  3474 KWIKN-KYGEDLRVTQIGQKGYLQIIEQALEAGAVVLIENLEESIDPVLGPLLGREVIKKG--RF 3535

  Fly  3051 IKLGDSVIEYNHSFRFYMTTKLRNPHYLPEVAVKVTLLNFMITTQGLQDQLLGITVARERPDLEA 3115
            ||:||...|||..||..:.|||.||||.||:..:.||:||.:|..||:||||...|:.||||||.
Human  3536 IKIGDKECEYNPKFRLILHTKLANPHYQPELQAQATLINFTVTRDGLEDQLLAAVVSMERPDLEQ 3600

  Fly  3116 EKNNLIVQGADNKRMLKETEDQILEVLSSAE-NILEDETAVQILSSAKALANDISEKQVITEATE 3179
            .|::|..|....|..||..||.:|..||||. |.|.:...|:.|...|..|.::.:|....:.||
Human  3601 LKSDLTKQQNGFKITLKTLEDSLLSRLSSASGNFLGETVLVENLEITKQTAAEVEKKVQEAKVTE 3665

  Fly  3180 KQIDIARLSYVPIAEHSTILFFTIVELANIDPMYQYSLVWFVNLYMSSIDNTEKVDDIAARLLDL 3244
            .:|:.||..|.|.|..:::|:|.:.:|:.|.||||:||..|..::..:::.....:.:..|:.:|
Human  3666 VKINEAREHYRPAAARASLLYFIMNDLSKIHPMYQFSLKAFSIVFQKAVERAAPDESLRERVANL 3730

  Fly  3245 RNHFTYSLYVNICRSLFERDKLLFSLILNINMMKHDNRIDNAEWMFLLTGGVGLENPYKNPTTWL 3309
            .:..|:|:|....|.|||.|||.:...|...::..:..::..|..|||...|  :....:|..:|
Human  3731 IDSITFSVYQYTIRGLFECDKLTYLAQLTFQILLMNREVNAVELDFLLRSPV--QTGTASPVEFL 3793

  Fly  3310 GVQNWDELCRLTNLTNFKGLREDFNENSAQWKPFFDSKSPQDNKDIPKSWDNRVSVFQKLLLLRV 3374
            ..|.|..:..|:::..|..|..|...::..||.|.:|:.|:..| :|:.|.|:.:: |:|.:||.
Human  3794 SHQAWGAVKVLSSMEEFSNLDRDIEGSAKSWKKFVESECPEKEK-LPQEWKNKTAL-QRLCMLRA 3856

  Fly  3375 FRPDKLVPAVLNFVSGELGERFVDPPQFDLMASFADSHCCVPLIFILTPGSDPTATLLKFAEDQG 3439
            .|||::..|:.:||..:||.::|.....|...||.:|....|:.|||:||.||    ||..|.||
Human  3857 MRPDRMTYALRDFVEEKLGSKYVVGRALDFATSFEESGPATPMFFILSPGVDP----LKDVESQG 3917

  Fly  3440 ------FGTNRLFSLSLGQGQGPIAMKMIDEGVKMGNWVVLQNCHLAASFMPLLEKICENLLPDA 3498
                  |......::||||||..:|...:|...|.|:||:|||.||.|.::..|||..|. ..:.
Human  3918 RKLGYTFNNQNFHNVSLGQGQEVVAEAALDLAAKKGHWVILQNIHLVAKWLSTLEKKLEE-HSEN 3981

  Fly  3499 THPDFRLWLTSYPADH-----FPVVVLQNGIKMTNEPPKGLRSNILRSMISDPISDPEWYESCTQ 3558
            :||:||:::::.||..     .|..:|:|.||:|||||.|:.:|:.:::  |..:. :..|.|::
Human  3982 SHPEFRVFMSAEPAPSPEGHIIPQGILENSIKITNEPPTGMHANLHKAL--DNFTQ-DTLEMCSR 4043

  Fly  3559 PRIFKQLIYSLCFFHAVIQERRYFGPIGWNIPYEFNETDLRISLMQLRMFLNQYETVNYDALRYL 3623
            ...||.::::||:||||:.|||.|||.|||..|.||..||.||:..|..||.....|.||.||||
Human  4044 ETEFKSILFALCYFHAVVAERRKFGPQGWNRSYPFNTGDLTISVNVLYNFLEANAKVPYDDLRYL 4108

  Fly  3624 TGECNYGGRVTDDWDRRTLKTILDKFYCPAVIDLE--------TPYYLDETGLYYVPVFKEVDLY 3680
            .||..|||.:|||||||..:|.|.:|..|.:::.|        .|..:|..|.:.         |
Human  4109 FGEIMYGGHITDDWDRRLCRTYLGEFIRPEMLEGELSLAPGFPLPGNMDYNGYHQ---------Y 4164

  Fly  3681 LNFTRDLPQISAPAIFGFHANADIMKDQKETDMLLSHTLLTQKLEKKQRVYVETLSRRFPENLSL 3745
            ::  .:||. .:|.::|.|.||:|             ..|||..||..|..:|...|
Human  4165 ID--AELPP-ESPYLYGLHPNAEI-------------GFLTQTSEKLFRTVLELQPR-------- 4205

  Fly  3746 PTYPTCPPFLALYQMSLKDTSASSDDSGGSK-----------ALTPEEVVTNVATDILDKLPKLF 3799
                               .|.:.|.:|.::           .||.:..|..:..:||:::...|
Human  4206 -------------------DSQARDGAGATREEKLFSWRWHCVLTIQGKVKALLEEILERVTDEF 4251

  Fly  3800 DRDAALLKYP--TLYHQSMNTVLVQEMVRFNVLLNTIRTSLITLRKGIKGLVVMSPAVEAVYKSV 3862
            :....:.|..  |.|    ..|..||..|.|:|...|:.||..|..|:||.:.|:..:|.:..::
Human  4252 NIPELMAKVEERTPY----IVVAFQECGRMNILTREIQRSLRELELGLKGELTMTSHMENLQNAL 4312

  Fly  3863 LIAKIPAMWAGKSYPSLKPLGSYVTDFLRRLEFLQHWF-DHGAPSTFWLSGFFFTQAFLTGAQQN 3926
            ....:|..||.::|||...|.::..|.|.|::.|:.|. |...|||.||:|||..|:|||...|:
Human  4313 YFDMVPESWARRAYPSTAGLAAWFPDLLNRIKELEAWTGDFTMPSTVWLTGFFNPQSFLTAIMQS 4377

  Fly  3927 YARKYVISIDLLAFDYEVLTVEEPQRQGLSGPEDGVFVYGIFLEGARWDRTGKYLAESRPRELFD 3991
            .|||....:|.:|...::  .::.:.:..|.|.:|.:::|:|:|||.||.....:.|::.::|..
Human  4378 TARKNEWPLDQMALQCDM--TKKNREEFRSPPREGAYIHGLFMEGACWDTQAGIITEAKLKDLTP 4440

  Fly  3992 TMPLIWLK--PLKRVDLPERHNYLCPMYKTAERRGVLSTTGHSTNFVVAMLLLCNPNTPVSHWII 4054
            .||::::|  |..:.|.  |..|.||:|||::|         ...:|....|....|.  |.|::
Human  4441 PMPVMFIKAIPADKQDC--RSVYSCPVYKTSQR---------GPTYVWTFNLKTKENP--SKWVL 4492

  Fly  4055 RGTALLCQL 4063
            .|.|||.|:
Human  4493 AGVALLLQI 4501

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dhc36C	NP_001369131.1	DHC_N2	746..1151	CDD:400618	117/420 (28%)
		DYN1	<984..3651	CDD:227570	984/2732 (36%)
		AAA_6	1281..1607	CDD:403853	168/325 (52%)
		AAA_8	2299..2561	CDD:403858	106/265 (40%)
		AAA_9	2950..3165	CDD:403859	96/215 (45%)
		Dynein_C	3779..4061	CDD:408026	87/286 (30%)
DNAH9	XP_011522005.1	DHC_N1	212..789	CDD:285571	41/247 (17%)
		DHC_N2	1295..1699	CDD:285579	118/419 (28%)
		P-loop_NTPase	1832..2062	CDD:304359	136/229 (59%)
		P-loop_NTPase	2146..2281	CDD:304359	54/142 (38%)
		AAA_7	2439..2710	CDD:289541	83/272 (31%)
		AAA_8	2788..3055	CDD:289546	107/273 (39%)
		MT	3067..3410	CDD:289543	106/365 (29%)
		AAA_9	3438..3650	CDD:289547	96/214 (45%)
		Dynein_heavy	3790..4491	CDD:281078	248/781 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5245
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100025
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.710