DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Dhc36C and Dnah5

DIOPT Version :9

Sequence 1:	NP_001369131.1	Gene:	Dhc36C / 35061	FlyBaseID:	FBgn0013810	Length:	4065	Species:	Drosophila melanogaster
Sequence 2:	NP_579943.3	Gene:	Dnah5 / 110082	MGIID:	107718	Length:	4621	Species:	Mus musculus

Alignment Length:	4196	Identity:	1263/4196 - (30%)
Similarity:	2053/4196 - (48%)	Gaps:	610/4196 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    99 ESGVAKANYMTMRLEREHFRRKLVELILHMDDDQDPELAAQCAVPFPD--------QEEREILRY 155
            |:..||...:.:.|:|.:   .|:|..:|...::...:|. |.:|..|        |..:::
Mouse   804 ENAFAKIKDLELLLDRVN---DLIEFRIHAILEEMSSMAL-CQLPQDDPLTCEEFLQMTKDL--- 861

  Fly   156 YYYIKHGIDTIH-----VSPLSKKILKRITDL-VPPLLYKWQTALNENIAEVRADYVFAMKKAVV 214
               ...|...:|     |.....:::..:.|: |||          |..||
Mouse   862 ---CVSGAQLLHFKSSLVEEAVNELINMLLDVDVPP----------EEAAE-------------- 899

  Fly   215 DFVLRHTVLDRLTKEGVGGKYDTAERREVQSMTNFWRYRYDENRNVLMKTLFCIHRSVASILELW 279
                      .:..|......:|:.|||..|                 :.|.....:.||.|.|.
Mouse   900 ----------NVCHENASPSGNTSGRREGHS-----------------EALASSFNAGASSLPLT 937

  Fly   280 SMKYKDKS---LIDSKELAKVESPFSLFTFVYLCGSHIDNGKTLLEESWYGEIHSSLLKASKRGQ 341
            :...|.|.   |.:::||.                ||.::..|           .:|||.: |..
Mouse   938 ATARKKKETEVLEEARELL----------------SHFNHQNT-----------DALLKVT-RNT 974

  Fly   342 LPDIRR---FTLVKRF----------------FNCVAAL------MTQQLEDI---------CI- 371
            |..|||   |:.:..|                |.....|      ||..||||         ||
Mouse   975 LEAIRRRIHFSHMINFRDSNDASKAKQNHLPIFRASVTLAIPNIAMTPALEDIQQTLNKAVECII 1039

  Fly   372 ---RSLKEYADFICDYG--HSNPGFEISVMLADEDTIQFNPSFSKV-QSELLRVIDSIMLSIQML 430
               :.:::::..:....  |..   :::.:..:||    :.|.::| ::||...::...:::. :
Mouse  1040 SVPKGVRQWSSELLSKRKMHER---KMAAVKNNED----SDSDAEVEENELQETLEIASINLP-I 1096

  Fly   431 PRIESKLYTDLIVSKKIFLTPTVPESIVQETKNRICAMLEEQRIGPELRLQDFDPFIDLINGSDA 495
            |......|.::..:|:|....:|..:::..||..:...::.           |..:..:......
Mouse  1097 PVQTQNYYKNISDNKEIVKLVSVLSTVISSTKKEVITSMDR-----------FKRYNHIWQKEKE 1150

  Fly   496 ERVGNFMESDATFEQYADMVYEYKEKEDRIAKEVWAVIRMGFYEFHRDKFITHLESLCR------ 554
            :.:..|:..:....::...:..::..|..|..|. ..||:|....:.......|.:..:
Mouse  1151 DTIMTFIAQNPLLPEFESRILYFQSLEQEINAEP-EYIRVGSIALYTADLKLSLTAETKAWMAVI 1214

  Fly   555 --------QLQLDLLARMVTDQQARITRLGKEYDAIAKKALTVPKDTAELMQL----------KA 601
                    :.:::.:..:|.:.|.:::|..|:.|.| :.|:...|:..| .|:          ::
Mouse  1215 GRHCNRKYRAEMENILTVVEESQKKLSRPIKDLDDI-RIAMAALKEIRE-QQISTDFQVGPIEES 1277

  Fly   602 YVVHAEENLVPEMEARLKVNMSEILWLMDHTLYSPLEIKNNSNSFQWYLKLPSIFEQHRAIIAEK 666
            |.:..:..|:...|...||:.....|  :..|....:::|...:.|     ||
Mouse  1278 YALLNKYGLLVAKEEMDKVDTLRYAW--EKLLARASDVQNELGALQ-----PS------------ 1323

  Fly   667 VIEYQELLKKRIELFRRELQNYYEQVQTYDTWGDIKQLSRYKKRAGVLDQRLVQAMETIDQINEE 731
               :::.|...:|:|.::.|.:|   ..||..|.:....:.::.:|    ||:......|.|..:
Mouse  1324 ---FRKELISTVEVFLQDCQQFY---LDYDLNGPMASGLKPQEASG----RLIIFQNQFDNIYRK 1378

  Fly   732 -------ETSYGWDLSQYPMRKKAHDQL-------KPYKTLFDAGQDFMDKWDLWMHSQVGSFDP 782
                   |..:|..::.||...:...||       ..|..:.:....:.|  .||....:
Mouse  1379 YITYTGGEELFGLPVTPYPQLLEIKRQLNLLQKIYSLYNNVIETVNSYQD--TLWSDVNI----- 1436

  Fly   783 DEIDGDVSNFYRIIQKLDKQMGDHPITMQLIQDVKAQIEAFREHMPIINTLGNPGMKARHWELVS 847
            ::|:.::..|....:||.:.:.|    .|...|:|..|:.|.|..|::..:.:..|..|||:.::
Mouse  1437 EKINNELLEFQNRCRKLPRALKD----WQAFLDLKKTIDDFSECCPLLEYMASNAMVERHWQRIT 1497

  Fly   848 EIIGFPIKVSPE-LTLEKIIEYQLDEYVPKFEAISESATKENNLERAMAKMVNEWEGVEFSISPY 911
            .:.|..:.|..| ..|..|:|..|.:|..:.|.|..||.||.::|:.:.:::|||:....:.|.:
Mouse  1498 ALTGHSLDVGNETFKLRNIMEAPLLKYKEEIEDICISAVKERDIEQKLRQVINEWDNKTLTFSGF 1562

  Fly   912 RDSGTFKLAAVDDIQIL--LDDQIIKTQTMKSSPYIKPFEADIIKWEAKLMLLQEILDEWLRVQA 974
            :..|...|......:::  ::|.::...::.|:.|..||:|.|.||...|....:|::.|:.||.
Mouse  1563 KTRGELLLRGDSTSEVIASMEDSLMLLGSLLSNRYNMPFKAQIQKWVQCLSNSTDIIENWMTVQN 1627

  Fly   975 TWMYLEPIFSSPDIQQQMPEEGRRFSAVDKIWKELMKQVSQDPKVM-VVVQIDKMNDKLKKAYSL 1038
            .|:|||.:|...||.:|:|:|.:|||.:||.|.::|.:..:.|.|: ..|..:.|...|......
Mouse  1628 LWIYLEAVFVGGDIAKQLPKEAKRFSNIDKSWVKIMTRAHEIPNVVQCCVGDETMGQLLPHLLDQ 1692

  Fly  1039 LEVIQKGLNAYLEKKRLYFPRFFFLSNDELLEILSETKDPTRVQIHLKKCFEGIATLNFTEELDV 1103
            ||:.||.|..|||||||.||||||:|:..|||||.:..|...:|.||...|:.|.|:.|.:::..
Mouse  1693 LEICQKSLTGYLEKKRLCFPRFFFVSDPALLEILGQASDSHTIQAHLLNVFDNIKTVKFHDKIYD 1757

  Fly  1104 TAMRSSEREEVTLVDVISTSKARGQVEKWLLELEIDMKKSVH-------HKVSEAFYSYLKMLRH 1161
            ..:..|.||..| :::.....|.|.||.||..|..:.:.|:|       ..:.|..:..::.|.
Mouse  1758 RILSISSREGET-IELDKPVMAEGNVEVWLNSLLEESQSSLHLVIRQAAANIQEPGFQLIEFLS- 1820

  Fly  1162 VWVLTWPGQC----VQSISLTYWTLEITECFESEEPKENLAKYLQKCVLQ---------INKIVD 1213
                ::|.|.    :|.:    ||.      :|||...| ||: .|.::|         :|.:::
Mouse  1821 ----SFPAQVGLLGIQML----WTR------DSEEALRN-AKF-DKKIMQKTNQAFLELLNMLIE 1869

  Fly  1214 LVRGDLNTQNRITLGALVVLDVHARDVLAEIVANQVEDLQDFQWLCQLRYYWEDNNLDTRMI--- 1275
            :...||::..|:....|:.:.||.||:..::....|:...||:||.|.|:|::::: |..||
Mouse  1870 ITTKDLSSMERVKYETLITIHVHQRDIFDDLCHMHVKSPTDFEWLKQCRFYFKEDS-DKTMIHIT 1933

  Fly  1276 NCSLPYGYEYLGNTPRLVVTPLTDRCYRTLFAALNLHLGGAPEGPAGTGKTETTKDLAKAVAKQC 1340
            :.:..|..|:||.|.|||:||||||||.||..||.:.:||||.|||||||||||||:.:.:.|..
Mouse  1934 DVAFIYQNEFLGCTDRLVITPLTDRCYITLAQALGMSMGGAPAGPAGTGKTETTKDMGRCLGKYV 1998

  Fly  1341 VVFNCSDGLDYLALGKFFKGLASCGAWSCFDEFNRIDLEVLSVVAQQILTIQRGINSGSPTLVF- 1404
            |||||||.:|:..||:.|||||..|:|.||||||||||.||||.||||..|.........:.:|
Mouse  1999 VVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIDLPVLSVAAQQISIILTCKKEHKKSFIFT 2063

  Fly  1405 EGTTLTLDPTCAVFITMNPGYAGRSELPDNLKALFRSVAMMVPDYALISEIELYSYGFLTAKPLS 1469
            :|..:|::|...:|:|||||||||.|||:|||..||||||||||..:|..::|.|.||:....|:
Mouse  2064 DGDNVTMNPEFGLFLTMNPGYAGRQELPENLKINFRSVAMMVPDRQIIIRVKLASCGFIDNVVLA 2128

  Fly  1470 VKIVATYRLCSEQLSTQCHYDYGMRAVKSVLKAAGALKLRYRDENEDILVLRSIKDVNLPKFLNQ 1534
            .|....|:||.||||.|.|||:|:|.:.|||:..||.|.....:.|..:|:|.::|:||.|.:::
Mouse  2129 RKFFTLYQLCEEQLSKQVHYDFGLRNILSVLRTLGAAKRASPTDTESTIVMRVLRDMNLSKLIDE 2193

  Fly  1535 DIPLFQGITSDLFPGTVLPEADYVLFNKCTQMACERQNKQC-----TPFVLEKVQQLYEMIVVRH 1594
            |.|||..:..||||..:|.:|.|...    :.|..:|.::.     .|:.| ||.||:|...|||
Mouse  2194 DEPLFLSLIEDLFPNILLDKAGYPEL----ETAISKQVEEAGLINHPPWKL-KVIQLFETQRVRH 2253

  Fly  1595 GLMLVGYPFGGKTTTYRVLAEALECMEKTD-GSENKAIYTVINPKAITMGQLYGQFDAVSHEWSD 1658
            |:|.:|....||||....|.:|:     || |..::.:.  :||||||..|::|:.|..:::|:|
Mouse  2254 GMMTLGPSGSGKTTCIHTLMKAM-----TDCGKPHREMR--MNPKAITAPQMFGRLDVATNDWTD 2311

  Fly  1659 GILAVNYRIFAISDSPDRKWLIFDGPVDAIWIENMNTVLDDNKKLCLMSGEIIQLSNTTNLVFEP 1723
            ||.:..:|....:...:..|::.|||||||||||:|:||||||.|.|.:|:.|.::....:||||
Mouse  2312 GIFSTLWRKTLKAKKGEHIWIVLDGPVDAIWIENLNSVLDDNKTLTLANGDRIPMAPNCKIVFEP 2376

  Fly  1724 MDLEVASPATVSRCGMIYLEPSSLGWEPLVASWKNTLPAAFHTVSKQLISMLISRFCPILLFILR 1788
            .:::.||||||||.||:::..|.|.|.|::..                             |:.|
Mouse  2377 HNIDNASPATVSRNGMVFMSSSVLDWSPILEG-----------------------------FLKR 2412

  Fly  1789 KSLKEIAPTSDANLMVSLMNFFECFIDDFRDEKYVANVSDLDFRAQT-------------EG--- 1837
            :|.:|      |.::..|  :.|.|.|.:|     .::.:|:|:.:.             :|
Mouse  2413 RSPQE------AEILRQL--YAETFPDLYR-----FSIQNLEFKMEVLEAFVITQSTHMLQGLIP 2464

  Fly  1838 ---------------IFLFSCIWSLGGSLDADSREKFNIIFRALMEKT--FPQ------SLYDTY 1879
                           :|:|:.:||:|..|:.:.|.:..:..|:....|  .||      :::|.|
Mouse  2465 PKEQAGEVDPEHLGRLFVFAMMWSVGAVLELEGRRRMELWLRSREGPTLHLPQLTDAGDTMFDYY 2529

  Fly  1880 GVPEDLYVE-SLAKP-FIFP---IPKQGSVFDYRYIKEGKGKWKPWQDDVNSAPPIPRDIPVNQI 1939
            ..|...:.. ||..| :::|   .|:.||                                   |
Mouse  2530 VAPNGTWRHWSLCTPEYVYPPDTTPEYGS-----------------------------------I 2559

  Fly  1940 IIQTNESVRIGAVLDLLNRHGKPIMLVGPTGTGKSVYVIDYMLKKMDLSFYKPLLISFSAQTSAN 2004
            ::...::||...::..:.:.||.::|:|..||.|:|.:..:| .|.|...:....::||:.|:..
Mouse  2560 LVPNVDNVRTDFLIKTIAKQGKAVLLIGEQGTAKTVIIKGFM-SKFDPESHMVKNLNFSSATTPV 2623

  Fly  2005 QTQDIIMSKLDKRRKGVFGPPLNSRFVIFVDDVSMPLKENYGAQPPIELLRMMLDHMMWYDRKNI 2069
            ..|..|.|.:|||....:|||...:..:|:||::||:...:|.|...|::|.:::...:|:.:.
Mouse  2624 MFQRTIESYVDKRMGTTYGPPAGKKMAVFIDDLNMPVINEWGDQVTNEIVRQLMEQSGFYNLEK- 2687

  Fly  2070 VP---MKLIDLQMIVAMGPPSTG-NTVTPRFQRFFNVISIDDFNNDILNTIFSKI-VLWHLDTRG 2129
             |   ..::|:|.:.||..|..| |.:..|.:|.|::.:....::..::.||..| ..::...||
Mouse  2688 -PGEFTSIVDIQFLAAMIHPGGGRNDIPQRLKRQFSIFNCTLPSDASMDKIFGVIGAGYYCAQRG 2751

  Fly  2130 FSKEFDPCIDEIVGATLTIYNDAKLNLLPTPAKSHYLFNLRDFSRVIQGVLLSVPEATEDVNSMR 2194
            ||:|....:.::|..|..::...||.:||||||.||:|||||.||:.||:|....|..:|.:.:.
Mouse  2752 FSEEVQDALIKLVPLTRRLWQMTKLKMLPTPAKFHYVFNLRDLSRIWQGMLNITSEVIKDTDELL 2816

  Fly  2195 RLWVHEVLRVYGDRLVEDADRSWLFENICSTVKSCFNTDPSRLFGRLVEKDKSLQESDFRQLIYC 2259
            |||.||..||..||....:|.:|..:.:.|.|:..|..:.:.:....|:            ..:.
Mouse  2817 RLWKHECKRVIADRFSMSSDVTWFDKAVVSLVEEEFGEEKAPVVDCGVD------------AYFV 2869

  Fly  2260 DF----------TNPKADT---KNYVEVQDLEELRRVVEAYLVEYN-NMSKKPMNLVLFRFAIEH 2310
            ||          |..:||.   |.|..:..|..||..:..:|..|| ::....|::|.|..|:.|
Mouse  2870 DFLRDAPEATGETPEEADAEMPKLYEPIASLNHLRERLSVFLQLYNESIRGTGMDMVFFIDAMVH 2934

  Fly  2311 LSRICRIIKQPRSHALLIGVGGSGRQSLTRLASHICDYELFQVEITRLYGPYEYHEDIKAILRKI 2375
            |.:|.|:|:.||.:|||:||||||:||||||||.|..|..||:.:||.|......||:|.:.|..
Mouse  2935 LVKISRVIRTPRGNALLVGVGGSGKQSLTRLASFIAGYTSFQITLTRSYNTSNLMEDLKVLYRTA 2999

  Fly  2376 GASEMHGVFLFTDVQIKDESFLEDISNLLNSGEVPNLFTNEEKIEVQEKMAQI-DKQRDKAVQTD 2439
            |.......|:|||.:||:|||||.::|:|:||||.|||..:|..|:...:..| .|:..:...|:
Mouse  3000 GQQGKGITFIFTDNEIKEESFLEYMNNVLSSGEVSNLFARDEIDEINSDLTPIMKKEHPRRPPTN 3064

  Fly  2440 GSPVALFNFFVTTCKDQLHIVLAMSPIGDALRNRIRKFPSIVNCCTIDWFQSWPEDALLAVSTRF 2504
            .:   |:.:|::..:..|||||..||:|:..|||..|||::::.||||||..||:|||:|||..|
Mouse  3065 DN---LYEYFMSRVRGNLHIVLCFSPVGEKFRNRALKFPALISGCTIDWFSRWPKDALVAVSEHF 3126

  Fly  2505 LASE--DLTALERRTAIDMCM-EFHTSTQELSAKFFSRLHRYNYVTPTSYLELIQTFKALLSQKR 2566
            |:|.  |.|| |.:..:..|| .|.....|..|.:|.|..|..:|||.|||..||.:|.:..:|.
Mouse  3127 LSSYTIDCTA-EIKKELVQCMGSFQDGVAEKCADYFQRFRRSTHVTPKSYLSFIQGYKFIYEEKH 3190

  Fly  2567 NNITNNRNRYLTGISQLDIAAQQVAVMQEQLIALEPKLKEASEIVAEQVAKVTADSKLAEE-QRE 2630
            ..:.:..||..||:.:|..|::.||.:.::|...|.:|:.|:|.....:.:||..::.||: :.|
Mouse  3191 MEVQSLANRMNTGLEKLKEASESVAALSKELAGKEKELQVANEKADTVLKEVTMKAQAAEKVKAE 3255

  Fly  2631 IVKLDESAAKEQAAVAQEIKDE--CDAKLGEALPILESALAALNTLTTADIAVVKTMKSPPIGVR 2693
            :.|:.:   |.||.|....||:  .:.||..|.|.||.|.|||.|:..:|||.|:|:..||..:.
Mouse  3256 VQKVKD---KAQAIVDSISKDKAIAEEKLEAAKPALEEAEAALQTIKPSDIATVRTLGRPPHLIM 3317

  Fly  2694 IVMEAVCILKDVKPDKVPNPSGLGTVEDYWGPSKRVLSDMKFLDSLLNFDKDNIPVEVMKKLAQR 2758
            .:|:.|.:|...:.:.|......|.....|..|.::::...||.:|..|.||.|..||::.|
Mouse  3318 RIMDCVLLLFQRRVNAVKIDVDKGCTMPSWQESLKLMTAGNFLQNLQQFPKDTINEEVIEFL--- 3379

  Fly  2759 ILSNEAFDPD--KIKSASTAC---EGLCRWVIALTKYDVVAKIVAPKKLALAEAEATYNAAMKTL 2818
               |..|:..  .|::|...|   .|||.|..|:..:..:.|.|.|.|..|...|..:..||:.|
Mouse  3380 ---NPYFEMSDYNIETAKRVCGNVAGLCSWTKAMASFFSINKEVLPLKANLIVQENRHILAMQDL 3441

  Fly  2819 NEKLAMLAKVEANLAAIQKILDEQLRQYGILLAEHEACTKKLQRAQELISGLGGERTRWSETAKM 2883
            .:..|.|...:|.|..:|...::.:.:...||.:.:.|..|:|.|..|||||.||:.||:|.:|.
Mouse  3442 QKAQAELDAKQAELDVVQAEYEQAMAEKQTLLEDADRCRHKMQTASTLISGLAGEKERWTEQSKE 3506

  Fly  2884 LQASFKSVTGDVLISSGVVSYLGPFTIDFRVDQIRKWVTKCLNFGVTCTADFQLAVVLGEPVEIR 2948
            ..|..|.:.||||:::..:||.|||..:||...:..|..:.....:.......|..:|.:...|.
Mouse  3507 FAAQTKRLVGDVLLATAFLSYSGPFNQEFRDLLLHDWKKEMKARKIPFGNGLNLNEMLIDAPTIS 3571

  Fly  2949 FWNICGLPTDAFSIESAIMMKNARRWPLMIDPQGQANKWIKNYEKNNKLCVIRLNQADYTRVMEN 3013
            .||:.|||.|..||::.|::..|.|:||:||||.|...||||.|..|:|.:..||...:...:|:
Mouse  3572 EWNLQGLPNDDLSIQNGIIVTKASRYPLLIDPQTQGKIWIKNKESQNELQITSLNHKYFRNHLED 3636

  Fly  3014 AIQFGLPVLLENIGEELDPVLESVLQKTLFKQGGALCIKLGDSVIEYNHSFRFYMTTKLRNPHYL 3078
            ::..|.|:|:|::||||||.|::||:|...|.|....:|:||..::....|:.|:||||.||.|.
Mouse  3637 SLSLGRPLLIEDVGEELDPALDNVLEKNFIKTGSTFKVKVGDKEVDVMDGFKLYITTKLPNPAYT 3701

  Fly  3079 PEVAVKVTLLNFMITTQGLQDQLLGITVARERPDLEAEKNNLIVQGADNKRMLKETEDQILEVLS 3143
            ||::.:.::::|.:|.:||:|||||..:..|:.:||.|:.:|:.....|||.:||.||.:|..|:
Mouse  3702 PEISARTSIIDFTVTVKGLEDQLLGRVILTEKQELEKERTHLLEDVTANKRRMKELEDNLLYRLT 3766

  Fly  3144 SAE-NILEDETAVQILSSAKALANDISEKQVITEATEKQIDIARLSYVPIAEHSTILFFTIVELA 3207
            |.: :::|||:.:.:||:.|..|.::::|..|:..||.||:.||..|.|:|...:||:|.|.|:.
Mouse  3767 STQGSLVEDESLIIVLSNTKKTAEEVTQKLEISGETEIQINSAREEYRPVATRGSILYFLITEMR 3831

  Fly  3208 NIDPMYQYSLVWFVNLYMSSIDNTEKVDDIAARLLDLRNHFTYSLYVNICRSLFERDKLLFSLIL 3272
            .::.|||.||..|:.|:..|:..:.|....:.|:.::..|.||.::....|.|:|..|.||:|:|
Mouse  3832 LVNEMYQTSLRQFLGLFDLSLARSVKSPITSKRIANIIEHMTYEVFKYAARGLYEEHKFLFTLLL 3896

  Fly  3273 NINMMKHDNRIDNAEWMFLLTGGVGLE---NPYKNPTTWLGVQNWDELCRLTNLTNFKGLREDFN 3334
            .:.:....|.:.:.|::.|:.||..|:   .|.| |:.|:....|..|..|:.|..|..:.:..:
Mouse  3897 TLKIDIQRNLVKHEEFLTLIKGGASLDLKACPPK-PSKWILDMTWLNLVELSKLKQFSDILDQIS 3960

  Fly  3335 ENSAQWKPFFDSKSPQDNKDIPKSWDNRVSVFQKLLLLRVFRPDKLVPAVLNFVSGELGERFVDP 3399
            .|...|:.:||.::|:: :.:|.::|..:..|::|||:|.:.||:.:.....::...:||.:.:.
Mouse  3961 RNEKMWRVWFDKENPEE-EPLPNAYDKSLDCFRRLLLIRSWCPDRTIAQARKYIMDSMGENYAEG 4024

  Fly  3400 PQFDLMASFADSHCCVPLIFILTPGSDPTATLLKFAEDQGFGTNRLFSLSLGQGQGPIAMKMIDE 3464
            ...||..::.:|....|||.:|:.|||||.:::...:.....|.   .:|:||||...|.|::.:
Mouse  4025 VILDLEKTWEESDPRTPLICLLSMGSDPTDSIIALGKRLKIETR---YVSMGQGQEVHARKLLHQ 4086

  Fly  3465 GVKMGNWVVLQNCHLAASFM-PLLEKICENLLPDATHPDFRLWLTSYPADHFPVVVLQNGIKMTN 3528
            .:..|.||:||||||...|: .|::.:.|.   :..|..||||:|:.....||:.:||..||..|
Mouse  4087 TMANGGWVLLQNCHLGLDFLDELMDVVTET---ETVHDTFRLWITTEVHKQFPITLLQMSIKFAN 4148

  Fly  3529 EPPKGLRSNILRSM--ISDPISD----PEWYESCTQPRIFKQLIYSLCFFHAVIQERRYFGPIGW 3587
            |||:|||:.:.|:.  :|..:.|    .:|          |.::|::.|.|:.:||||.|||:||
Mouse  4149 EPPQGLRAGLRRTYGGVSQDLLDVSVGAQW----------KPMLYAVAFLHSTVQERRKFGPLGW 4203

  Fly  3588 NIPYEFNETDLRISLMQLRMFLNQYET---VNYDALRYLTGECNYGGRVTDDWDRRTLKTILDKF 3649
            |||||||:.|...::..::..|:..:.   |::..:||:.||..||||||||:|:|.|.|....:
Mouse  4204 NIPYEFNQADFNATVQFIQNHLDDMDVKKGVSWTTVRYMIGEIQYGGRVTDDYDKRLLNTFAKVW 4268

  Fly  3650 YCPAVIDLETPYYLDETGLYYVPVFKEVDLYLNFTRDLPQISAPAIFGFHANADIMKDQKETDML 3714
            :...:...:..:|..    |.:|....||.||.:.:.||...:|.:||.|.||||....|....:
Mouse  4269 FSENMFGPDFTFYQG----YNIPKCSTVDGYLQYIQSLPAYDSPEVFGLHPNADITYQSKLAKDV 4329

  Fly  3715 LSHTLLTQKLEKKQRVYVETLSRRFPENLSLPTYPTCPPFLALYQMSLKDTSASSDDSGGSKALT 3779
            |...|..|.                                       ||:|...|:       |
Mouse  4330 LDTILGIQP---------------------------------------KDSSGGGDE-------T 4348

  Fly  3780 PEEVVTNVATDILDKLPK---LFDRDAALLKYPTLYHQSMNTVLVQEMVRFNVLLNTIRTSLITL 3841
            .|.||..:|.|:|:|||:   .|:....|.|....  |.||..|.||:.|...:|:.:|::|..|
Mouse  4349 REAVVARLADDMLEKLPEDYSPFEVKERLQKMGPF--QPMNIFLRQEIDRMQRVLSLVRSTLTEL 4411

  Fly  3842 RKGIKGLVVMSPAVEAVYKSVLIAKIPAMWAGKSYPSLKPLGSYVTDFLRRLEFLQHWFDHGAPS 3906
            :..:.|.::||..:......:..|:|||.|...|:.| ..||.:.|:.|.|......|..:|.|.
Mouse  4412 KLAVDGTIIMSENLRDALDCMFDARIPARWKKASWVS-STLGFWFTELLERNCQFTSWVSNGRPH 4475

  Fly  3907 TFWLSGFFFTQAFLTGAQQNYARKYVISIDLLAFDYEVL--TVEEPQRQGLSG-PEDGVFVYGIF 3968
            .||::|||..|.|||..:|...|    :....|.|..||  .|.:..:..:|. |.:||:|||::
Mouse  4476 CFWMTGFFNPQGFLTAMRQEITR----ANKGWALDNMVLCNEVTKFMKDDISAPPTEGVYVYGLY 4536

  Fly  3969 LEGARWDRTGKYLAESRPRELFDTMPLIWLKPLKRVDLPERHN------YLCPMYKTAERRGVLS 4027
            ||||.||:....|.||:|:.||:.||:|.:       ..|.:.      |.||:||...|..:
Mouse  4537 LEGAGWDKRNMKLIESKPKVLFELMPVIRI-------FAENNTARDPRLYCCPIYKKPVRTDL-- 4592

  Fly  4028 TTGHSTNFVVAMLLLCNPNTPVSHWIIRGTALLCQL 4063
                  |::.|:.|. ....| .||::||.||||.:
Mouse  4593 ------NYIAAVDLK-TAQAP-EHWVLRGVALLCDV 4620

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dhc36C	NP_001369131.1	DHC_N2	746..1151	CDD:400618	124/422 (29%)
		DYN1	<984..3651	CDD:227570	954/2786 (34%)
		AAA_6	1281..1607	CDD:403853	164/331 (50%)
		AAA_8	2299..2561	CDD:403858	119/265 (45%)
		AAA_9	2950..3165	CDD:403859	88/215 (41%)
		Dynein_C	3779..4061	CDD:408026	97/293 (33%)
Dnah5	NP_579943.3	Stem. /evidence=ECO:0000250	1..1938		282/1303 (22%)
		DHC_N1	248..802	CDD:285571
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	901..921		6/36 (17%)
		DHC_N2	1402..1804	CDD:285579	124/413 (30%)
		P-loop_NTPase	1939..2170	CDD:304359	130/230 (57%)
		AAA 1. /evidence=ECO:0000250	1939..2161		127/221 (57%)
		AAA 2. /evidence=ECO:0000250	2221..2440		89/268 (33%)
		P-loop_NTPase	2254..2389	CDD:304359	59/141 (42%)
		AAA 3. /evidence=ECO:0000250	2547..2800		78/290 (27%)
		P-loop_NTPase	2558..2822	CDD:304359	83/301 (28%)
		AAA 4. /evidence=ECO:0000250	2913..3167		111/257 (43%)
		P-loop_NTPase	2914..3183	CDD:304359	120/272 (44%)
		Stalk. /evidence=ECO:0000250	3182..3479		88/305 (29%)
		MT	3199..3543	CDD:289543	113/352 (32%)
		AAA 5. /evidence=ECO:0000250	3564..3794		91/229 (40%)
		AAA_9	3572..3788	CDD:289547	88/215 (41%)
		Dynein_heavy	3929..4610	CDD:281078	235/772 (30%)
		AAA 6. /evidence=ECO:0000250	4009..4223		78/229 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5245
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100025
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.710