Protein Alignment mEFTs and tsfm-1

DIOPT Version :9

• Sequence 1: NP_609847.1
• Gene: mEFTs / 35060
• FlyBaseID: FBgn0032646
• Length: 318
• Species: Drosophila melanogaster
• Sequence 2: NP_506079.1
• Gene: tsfm-1 / 179683
• WormBaseID: WBGene00010094
• Length: 316
• Species: Caenorhabditis elegans
• Alignment Length: 335
• Identity: 113/335 - (33%)
• Similarity: 169/335 - (50%)
• Gaps: 69/335 - (20%)

  Fly     7 FTRALHSTRQLYAGSGGSGGLEKSALAALRKKTGYTFANCKKAL-EKHNNDVGLAEKWLHEQAQT 70
            |.|.|.:|.:..|.:  ...:.|.||.||||||||::.||:||| :...||:..|.|||.|.|..
 Worm     7 FVRLLSTTSRNLAEA--EKKVSKEALMALRKKTGYSYVNCRKALIQFGENDMDSAVKWLKEAAAK 69

  Fly    71 LGWSKATKVADRATAHGLIGVLIRGNRGAMVELNCETDFVARNDTFKRFVDHVACMCL------- 128
            .||:||.|:..|.|::||:.|:...:..|:|||:||||||||:..||..:.:::...|
 Worm    70 EGWAKAAKLGTRVTSNGLVSVVTDNSTAAVVELSCETDFVARSGAFKDLLSNISNSVLAKAKPQS 134

  Fly   129 --------QYT----DLTDFDGDLWKLGFDADALRNLRTEEGRTLGDHLALLIGAIGENATIRRA 181
                    ::|    ||||.||            :|:|        :.|:|.||.:|||.|:||.
 Worm   135 ISSGSKLQEFTYDLGDLTDSDG------------KNMR--------EVLSLSIGKLGENMTVRRV 179

  Fly   182 LCFKANNDLKLVGYAHPAPTNVGTTEGITQVGKYGAIVAYRSTHP--LLDFEFHKSICQQIVGMK 244
            ..|||.....|.|.:||..   ||.:  ..:|::.:::|...:.|  :...:....|||.|:||.
 Worm   180 KAFKAPEGTTLFGASHPKD---GTDD--IPMGRFISLIALNQSSPGSISSQQLAGQICQHIIGMS 239

  Fly   245 PTKIGEYDK--------------DKPAE-----NKDD-ETCLIHQEYLLDADKTVGEALQEHNCE 289
            |..:||..:              |..|:     |.|: ||.|:.|.::|:..::|.|.|:.||..
 Worm   240 PESLGEAAESVKTQEGLRSQEGHDPNADPVVVTNIDESETALLRQAFMLNPSQSVHEYLKSHNAN 304

  Fly   290 IVDYHRFECG 299
            |:|:.|.|.|
 Worm   305 ILDFVRVELG 314

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mEFTs	NP_609847.1	UBA_EF-Ts	32..66	CDD:270461	20/34 (59%)
		Tsf	35..303	CDD:223342	104/307 (34%)
		EF_TS	98..300	CDD:279261	74/243 (30%)
tsfm-1	NP_506079.1	tsf	25..187	CDD:183447	71/181 (39%)
		UBA_EF-Ts	28..65	CDD:270461	21/36 (58%)
		EF_TS	97..314	CDD:279261	73/241 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165223
Domainoid	1	1.000	79	1.000	Domainoid score	I5637
eggNOG	1	0.900	-	-		E1_COG0264
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4184
Inparanoid	1	1.050	161	1.000	Inparanoid score	I2856
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54697
OrthoDB	1	1.010	-	-		D1048278at2759
OrthoFinder	1	1.000	-	-		FOG0003815
OrthoInspector	1	1.000	-	-		oto17312
orthoMCL	1	0.900	-	-		OOG6_101036
Panther	1	1.100	-	-	LDO	PTHR11741
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R369
SonicParanoid	1	1.000	-	-		X2659
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.800