Protein Alignment mEFTs and TSFM

DIOPT Version :10

• Sequence 1: NP_609847.1
• Gene: mEFTs / 35060
• FlyBaseID: FBgn0032646
• Length: 318
• Species: Drosophila melanogaster
• Sequence 2: NP_001166167.1
• Gene: TSFM / 10102
• HGNCID: 12367
• Length: 346
• Species: Homo sapiens
• Alignment Length: 312
• Identity: 120/312 - (38%)
• Similarity: 165/312 - (52%)
• Gaps: 31/312 - (9%)

  Fly    18 YAGSG-GSGGLEKSALAALRKKTGYTFANCKKALEKHNNDVGLAEKWLHEQAQTLGWSKATKVAD 81
            |||.. .:....|..|..||:||||:|.|||||||....|:..||.|||::||..|||||.|:..
Human    35 YAGPRLSASASSKELLMKLRRKTGYSFVNCKKALETCGGDLKQAEIWLHKEAQKEGWSKAAKLQG 99

  Fly    82 RATAHGLIGVLIRGNRGAMVELNCETDFVARNDTFKRFVDHVA------CMCLQ-----YTD--- 132
            |.|..||||:|..||...:||:|||||||:||..|:..|..||      |..|:     |:.
Human   100 RKTKEGLIGLLQEGNTTVLVEVNCETDFVSRNLKFQLLVQQVALGTMMHCQTLKDQPSAYSKVQW 164

  Fly   133 LTDFDGDLWKL-------GF-DADALRNLRTEEGR--TLGDHLALLIGAIGENATIRRALCFKAN 187
            ||..:..||:.       || ::..|..|.....|  :|.|.|||.||.:|||..::||...|..
Human   165 LTPVNLALWEAEAGGSLEGFLNSSELSGLPAGPDREGSLKDQLALAIGKLGENMILKRAAWVKVP 229

  Fly   188 NDLKLVGYAHPAPTNVGTTEGITQVGKYGAIVAYRSTHPLLDFE-FHKSICQQIVGMKPTKIGEY 251
            :...:..|.|.|..:....:.:  :|||||:|...::....:.| ..:.:.|.:|||.|..:|..
Human   230 SGFYVGSYVHGAMQSPSLHKLV--LGKYGALVICETSEQKTNLEDVGRRLGQHVVGMAPLSVGSL 292

  Fly   252 DKDKPAENKDDETCLIHQEYLLDADKTVGEALQEHNCEIVDYHRFECGEHTE 303
            | |:|  ..:.||.::.|.||||...|:|:.:|.....:||:.||||||..|
Human   293 D-DEP--GGEAETKMLSQPYLLDPSITLGQYVQPQGVSVVDFVRFECGEGEE 341

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mEFTs	NP_609847.1	Tsf	34..300	CDD:440034	112/290 (39%)
TSFM	NP_001166167.1	Tsf	48..334	CDD:440034	109/290 (38%)