DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment qua and Capg

DIOPT Version :9

Sequence 1:	NP_001246066.1	Gene:	qua / 35058	FlyBaseID:	FBgn0003187	Length:	892	Species:	Drosophila melanogaster
Sequence 2:	NP_001035999.1	Gene:	Capg / 12332	MGIID:	1098259	Length:	349	Species:	Mus musculus

Alignment Length:	356	Identity:	85/356 - (23%)
Similarity:	156/356 - (43%)	Gaps:	47/356 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 IWKIDEDRLEAVQRSHYGTFYDSCAYIIYAASLSGHYANHETITREQKPNVSLERYIHYWLGKNV 102
            ||::::.:...:.|..:|.|:...:|::.      |....|.            .::|.|:|:..
Mouse    23 IWRVEKLKPVPIARESHGIFFSGDSYLVL------HNGPEEA------------SHLHLWIGQQS 69

  Fly   103 SEQNRSNVVHKIQELDSYLGNISSIYRETQNLESARFLSYFKKGYEFR--------FSVRSGALI 159
            |...:.........|::.||.....:||.|..||..|:|||.:|.::|        ....|||..
Mouse    70 SRDEQGACAVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYREGGVESAFHKTTSGATP 134

  Fly   160 SAPQRPRLFQLYARKWLRSIEVATIDWSHFNSDYVMVLQTDNLTYVWIGRSSSGIERRSALDWV- 223
            :|.:  :|:|:..:|.:|:.|.| :.|..||:....:|......:.|.|..|:.:||..|.|..
Mouse   135 AAIR--KLYQVKGKKNIRATERA-LSWDSFNTGDCFILDLGQNIFAWCGGKSNILERNKARDLAL 196

  Fly   224 ----QKHCSGSPITIVDDGYEQAMSQEHKELWNTMLPLKKRMVCQASQLVSEYADY-NSNKFRIY 283
                .:....:.:.|:.||.|.|      |:...:.|  |..:.:.:......||. |:....:|
Mouse   197 AIRDSERQGKAQVEIITDGEEPA------EMIQVLGP--KPALKEGNPEEDITADQTNAQAAALY 253

  Fly   284 KCNQ-RGRLHLDQLDVGMPAKDDLSDAHGVYLLDN--YGQSIWLWVGGQAPQADALSAMGNGRAF 345
            |.:. .|:::|.::....|...:|......::|||  .|: |::|.|.:|.:.:..:|:.....|
Mouse   254 KVSDATGQMNLTKVADSSPFASELLIPDDCFVLDNGLCGK-IYIWKGRKANEKERQAALQVADGF 317

  Fly   346 VKKKKYPDNTLVVRVLEGHEPVEFKRLFANW 376
            :.:.:|..||.|..:.:|.|...||:.|.||
Mouse   318 ISRMRYSPNTQVEILPQGRESPIFKQFFKNW 348

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
qua	NP_001246066.1	ADF_gelsolin	26..147	CDD:301701	24/108 (22%)
		gelsolin_like	164..254	CDD:200436	23/94 (24%)
		gelsolin_S3_like	276..375	CDD:200448	26/101 (26%)
		GEL	424..526	CDD:214590
		ADF_gelsolin	551..625	CDD:301701
		gelsolin_like	689..780	CDD:200436
		VHP	857..892	CDD:128458
Capg	NP_001035999.1	gelsolin_S1_like	17..120	CDD:200446	26/114 (23%)
		gelsolin_S2_like	139..226	CDD:200445	23/93 (25%)
		gelsolin_S3_like	247..347	CDD:200448	25/100 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1376537at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11977
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920