Protein Alignment GCS2beta and prkcsh

DIOPT Version :10

• Sequence 1: NP_609844.1
• Gene: GCS2beta / 35056
• FlyBaseID: FBgn0032643
• Length: 548
• Species: Drosophila melanogaster
• Sequence 2: XP_012808607.1
• Gene: prkcsh / 394983
• XenbaseID: XB-GENE-5843768
• Length: 552
• Species: Xenopus tropicalis
• Alignment Length: 547
• Identity: 210/547 - (38%)
• Similarity: 308/547 - (56%)
• Gaps: 51/547 - (9%)

  Fly    14 LLLALVATNVGSASEVPRPLGVPLAKASLYQPRAGENSWTCLDGSRTIPFSHINDDYCDCADGSD 78
            |||.||......|.||.||.||.|:..:.|.   ....:|||||||||||..:||||||||||:|
 Frog    45 LLLLLVGVLGCWAVEVKRPRGVSLSNRAFYD---DSKPFTCLDGSRTIPFDRVNDDYCDCADGTD 106

  Fly    79 EPGTAACPQGQFHCVNKGHQPVNIPSSQVQDGICDCCDGSDESETVG-CPNTCLELGAAAAVQRR 142
            ||||:||..|:|||.|.|::|..||||::.||||||||.:||..:.. |.|||.|:|.....:.:
 Frog   107 EPGTSACSNGRFHCTNAGYKPQYIPSSRINDGICDCCDTTDEYNSGALCENTCREMGKKEREELQ 171

  Fly   143 NAAELHKRGAERRQEMITRGKQMRAEREARRLELDQRRK----EQELLRAEKEQLKQTAEALEAE 203
            .|||:.:.|...:|.:|...::.|.|::.:..::.|||:    :.:.||.:||:    ||..|.|
 Frog   172 MAAEIAREGFRVKQLLIEDARKGREEKQTKLQDMVQRRQALQSQVDALRLQKEE----AEKPEQE 232

  Fly   204 AIEIFKEQQREVDADTAQAEREPQQMRQEATLTFVRYDTNKDGFVEVTELMVDMNLDRDRNGVVT 268
            |    |:..::...:..:||: .::.:|.:...|...|.:.||.:..:||...|.||.|.:|.::
 Frog   233 A----KDAHQKAWEEHKEAEK-AEEDKQRSLEVFTELDQDSDGMLAASELRSHMELDVDGDGAMS 292

  Fly   269 VEEAKYFLDERERVDLDAFVTLAWPRIKSLQMLAEGLFQPPQPEEVAQQPEVTTESIQPTPP--K 331
            .|||:..|.:.. ||:..|....||:|:               |:...:.:.     |..||  :
 Frog   293 DEEAQSLLGDTS-VDVGIFQESVWPQIR---------------EKFKSETDA-----QAVPPIEE 336

  Fly   332 LSEEQAELAGDDDIEADEEGEEDQYDDEEPDVGVGEASPDAEEATP--PNYDPETQRLIQQANEA 394
            .:|...|:..|:|.|..:|||:|:.|:.|.|:.|..:.  |:||.|  |.||..||.||..|..|
 Frog   337 PTESHPEVPEDEDEEDGDEGEDDEEDEPEEDIRVPPSK--AQEAEPEMPPYDEVTQALIDAAQTA 399

  Fly   395 RNALEEVERSLREIQQEVNEIDDQNNKGYGLTEEWAVHDGQCYNFEDREYVYTLCPFDRASQKSR 459
            |:..||.|:|||:::..:..::.:.:..:|.|.|::...|:||.....||||.||||:|.:||.:
 Frog   400 RSTYEEAEKSLRDMEDTIKGLEKEISLDFGPTGEFSYLYGECYELSTSEYVYRLCPFNRVTQKPK 464

  Fly   460 SGGPETTLGRWDKWSG-EPKQYSQQKYTNGAACWNGPNRSAIINISCALEPKITAVSEPNRCEYY 523
            .||.||.||.|..|:| |..::|..|:.:|.:||.|||||.::.:||..:..:|:.|||:||||.
 Frog   465 HGGSETNLGSWGSWAGPEDNKFSFMKFEHGTSCWQGPNRSTLVKLSCGKDSILTSTSEPSRCEYL 529

  Fly   524 FEFETPAAC--DSEAFQSESENLHDEL 548
            .||.|||||  ..|....:    ||||
 Frog   530 MEFFTPAACHPPPEVLPDD----HDEL 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GCS2beta	NP_609844.1	PRKCSH-like	26..193	CDD:372423	79/171 (46%)
		SMC_prok_B	<154..428	CDD:274008	80/281 (28%)
		PRKCSH	398..547	CDD:414904	62/151 (41%)
prkcsh	XP_012808607.1	PRKCSH-like	64..215	CDD:372423	70/153 (46%)
		PRKCSH	406..552	CDD:414904	61/149 (41%)