DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GCS2beta and Gnptg

DIOPT Version :9

Sequence 1:	NP_001246063.1	Gene:	GCS2beta / 35056	FlyBaseID:	FBgn0032643	Length:	548	Species:	Drosophila melanogaster
Sequence 2:	XP_006245997.1	Gene:	Gnptg / 287134	RGDID:	1311614	Length:	318	Species:	Rattus norvegicus

Alignment Length:	136	Identity:	38/136 - (27%)
Similarity:	59/136 - (43%)	Gaps:	26/136 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   434 GQCYNFEDREYVYTLCPFDRASQKSR-------SGGPETTLGRWDKWSGEPKQYSQQKYTNGAAC 491
            |:|::..:..|.|..|||...:|..:       ||    .||.|.:|......:.....|:|.:|
  Rat    69 GKCFSLVESTYKYEFCPFHNVTQHEQTFRWNAYSG----ILGIWHEWEIVNNTFKGMWMTDGDSC 129

  Fly   492 WNGPNRSAIINISCALEPKITAVSEPNRCEYYFEFETPAACD----------SEAFQSE----SE 542
             :..:|.:.:.::|....::..||||:.|.|...||||..|.          |||.|..    .:
  Rat   130 -HSRSRQSKVELTCGKTNRLAHVSEPSTCVYALTFETPLVCHPHSLLVYPTLSEALQQRWDQVEQ 193

  Fly   543 NLHDEL 548
            :|.|||
  Rat   194 DLADEL 199

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GCS2beta	NP_001246063.1	PRKCSH-like	26..193	CDD:193472
		LDLa	85..120	CDD:238060
		PRKCSH	398..547	CDD:297835	35/133 (26%)
Gnptg	XP_006245997.1	PRKCSH	69..129	CDD:285195	16/63 (25%)
Gnptg	XP_006245997.1	DMAP_binding	178..>261	CDD:283995	8/22 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2397
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D632472at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820