Protein Alignment cass and api5

DIOPT Version :10

• Sequence 1: NP_477454.1
• Gene: cass / 35053
• FlyBaseID: FBgn0286781
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_955834.2
• Gene: api5 / 321676
• ZFINID: ZDB-GENE-030131-395
• Length: 529
• Species: Danio rerio
• Alignment Length: 538
• Identity: 245/538 - (45%)
• Similarity: 332/538 - (61%)
• Gaps: 29/538 - (5%)

  Fly     4 IERLYKCYEILSEAGDKISEHVDEYKEILKAVKGTSKEKRLASQFIGNFFKHFPDLADTAIDAQF 68
            :|.||:.|.||::|.:.:|.|.|.|:.||..|||.:||||||:|||..||..||:|||.||:||.
Zfish     5 VEELYRNYGILADAKEDLSTHKDAYQVILDGVKGGAKEKRLAAQFIPKFFSSFPELADAAINAQL 69

  Fly    69 DLCEDDDTQIRRQAIKDLPKLCQGNADATIRVGDTLAQLLILDDPTELQQVNNSLLAIIKLDTKS 133
            |||||:|..|||||||:||:...|  :...||.|.|.|||..||..|..|||.:|::|.|:|.|.
Zfish    70 DLCEDEDVSIRRQAIKELPRFASG--ENLPRVADILTQLLQTDDSAEFNQVNTALISIFKIDAKG 132

  Fly   134 SIAGLFQQISTGDETTRERCLKFIATKLLTMGPTVITKEIEDYIVEEIKKALQDVTADEFHLCMT 198
            ::.|||.||..|::..|||.:||::|||.||...::|||:||||..|.||.|:|||.:||.|.|.
Zfish   133 TLGGLFSQILQGEDIVRERAIKFLSTKLKTMPEDIMTKEVEDYIFVETKKVLEDVTGEEFVLLMR 197

  Fly   199 ILGATKLGSTITGHAELVKLATEQAELNNTDADIIAVDDEVVERFIQCASAAAPYFSKTIKSTAF 263
            ||...|...|::|..:||:|..|||.|...   :...|.:.|:|.:||...|.|.|||.:.||.|
Zfish   198 ILSGLKSMQTVSGRQQLVELVVEQAFLEQA---LNPADTDSVDRLLQCTRQALPLFSKNVHSTRF 259

  Fly   264 VAHVCDKLLPIKTWNMIATAVSQDQIQLRLLKVFAEMITNTDKLDNASERINAVYNVLLEYMPLP 328
            |.:.|:.:||  ..:.:.:.|::..|||.:||:.|||......:|.....:|.::..|||:||||
Zfish   260 VTYFCEFVLP--NLSQLTSPVAELDIQLEVLKLLAEMSPYCGDMDKLEVNLNMLFEKLLEFMPLP 322

  Fly   329 --KLSDEDLGDTPPSFQFSHAECLLYALHTLGKNHPNSLSFVEDAEKLKDFRARLQYLARGTQGY 391
              :.:.|:..:..|..|||:.||||::.|.|||..|:.|.....|||||||:.||||.|||.|.|
Zfish   323 PEEENGENAANEEPKLQFSYVECLLFSFHQLGKKLPDFLIDKVSAEKLKDFKIRLQYFARGLQVY 387

  Fly   392 IKKLEESLKGKTGEELKTEENQLKQTALKTTSNINILIRDLFHSPPIFKHDIVLSWIVPKNNKLG 456
            |::|..:|:||||:.|||:||::|..|||.|:|||:||:||||:||.:|..:.|||     ..:.
Zfish   388 IRQLRVALQGKTGDALKTDENKIKVVALKITNNINVLIKDLFHNPPSYKSTVTLSW-----KPVQ 447

  Fly   457 KRHAPITFGEKAAANGKDKDQEPEKKSRPSN-----DQKFYSPPSGKYSNKV-NQSYGNNNRTRQ 515
            |..|....|:| ..:|:|.......|..|:|     .::.|:|||||||..: |.||      .|
Zfish   448 KTEAAAAIGQK-RRSGEDIGATATTKKHPTNLPRRDARQIYNPPSGKYSASIGNFSY------EQ 505

  Fly   516 RGG--GGGGGSGGGYRNR 531
            |||  ||.|...||..||
Zfish   506 RGGFRGGRGRGFGGRGNR 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cass	NP_477454.1	API5	4..516	CDD:428672	234/519 (45%)
api5	NP_955834.2	API5	5..503	CDD:428672	232/510 (45%)