Protein Alignment cass and api5

DIOPT Version :9

• Sequence 1: NP_477454.1
• Gene: cass / 35053
• FlyBaseID: FBgn0286781
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: XP_002937342.2
• Gene: api5 / 100380157
• XenbaseID: XB-GENE-963038
• Length: 523
• Species: Xenopus tropicalis
• Alignment Length: 538
• Identity: 240/538 - (44%)
• Similarity: 337/538 - (62%)
• Gaps: 29/538 - (5%)

  Fly     1 MDNIERLYKCYEILSEAGDKISEHVDEYKEILKAVKGTSKEKRLASQFIGNFFKHFPDLADTAID 65
            |..:|.||:.|.||::|.|.:.:|...|:.||..|||.:||||||:|||..||||||:|:|.|::
 Frog     1 MPTVEELYRNYGILADAKDDVGQHKSAYQVILDGVKGGAKEKRLAAQFIPKFFKHFPELSDAALN 65

  Fly    66 AQFDLCEDDDTQIRRQAIKDLPKLCQGNADATIRVGDTLAQLLILDDPTELQQVNNSLLAIIKLD 130
            ||.|||||::..|||||||:|.:...|  :...||.|.|.|||..||..|...|||:||:|.|:|
 Frog    66 AQLDLCEDEEVSIRRQAIKELSQFATG--ENLPRVADILTQLLQSDDSAEFNLVNNALLSIFKMD 128

  Fly   131 TKSSIAGLFQQISTGDETTRERCLKFIATKLLTMGPTVITKEIEDYIVEEIKKALQDVTADEFHL 195
            .|.::.|||.||..|::..|||.:||:|||:.|:...::|||::|||..|.||.|.|||.:||.|
 Frog   129 AKGTLGGLFSQILQGEDIVRERAIKFLATKMKTLPDEILTKEVDDYIFSESKKVLYDVTGEEFVL 193

  Fly   196 CMTILGATKLGSTITGHAELVKLATEQAELNNTDADIIAVDDEVVERFIQCASAAAPYFSKTIKS 260
            .|.||.|.|...|::|..:||.|.:|||.|:.:   :...|.:.|:|.:||...|.|.|||.:.|
 Frog   194 FMKILSALKNLQTVSGRQQLVDLVSEQAGLHQS---LNPADPDSVDRLLQCMRQAVPLFSKNVHS 255

  Fly   261 TAFVAHVCDKLLPIKTWNMIATAVSQDQIQLRLLKVFAEMITNTDKLDNASERINAVYNVLLEYM 325
            |.||.:.|:::|||.: ::.:.|...| :||.:||:.|||.:....:|.....:|.:::.|||:|
 Frog   256 TKFVTYFCEQVLPILS-SLTSPAEGID-VQLEVLKLLAEMSSFCGDMDKLESNLNKLFDKLLEFM 318

  Fly   326 PLPKLSDEDLGDT----PPSFQFSHAECLLYALHTLGKNHPNSLSFVEDAEKLKDFRARLQYLAR 386
            |||....|: ||:    .|..|||:.||||::.|.||:..|:.|....||||||||:.||||.||
 Frog   319 PLPPEEVEN-GDSAANEEPKLQFSYVECLLFSFHQLGRKLPDFLIAKVDAEKLKDFKIRLQYFAR 382

  Fly   387 GTQGYIKKLEESLKGKTGEELKTEENQLKQTALKTTSNINILIRDLFHSPPIFKHDIVLSW-IVP 450
            |.|.||::|..:|:||:|:.||||||::|..|||.|:|||:||:||||:||.:|..:.||| .|.
 Frog   383 GLQVYIRQLRLALQGKSGDALKTEENKIKVVALKITNNINVLIKDLFHNPPSYKSTVTLSWKPVQ 447

  Fly   451 KNNKLGKRHAPITFGEKAAANGKDKDQEPEKK-SRPSND-QKFYSPPSGKYSNKVN----QSYGN 509
            |.:.          |:|..::.......|:|. ..|..| ::.|:|||||||:.|.    :..|.
 Frog   448 KTDS----------GQKRTSDETSSSSPPKKPIVGPKRDSRQIYNPPSGKYSSNVGAFAYEQRGG 502

  Fly   510 NNRTRQRGGGGGGGSGGG 527
            .:.:|.||.||.|....|
 Frog   503 FHGSRGRGWGGRGNRSRG 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cass	NP_477454.1	API5	4..505	CDD:283550	231/511 (45%)
api5	XP_002937342.2	API5	4..502	CDD:368669	231/515 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	403	1.000	Domainoid score	I714
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4809
Inparanoid	1	1.050	404	1.000	Inparanoid score	I1859
OMA	1	1.010	-	-		QHG54362
OrthoDB	1	1.010	-	-		D1385954at2759
OrthoFinder	1	1.000	-	-		FOG0006081
OrthoInspector	1	1.000	-	-		oto102578
Panther	1	1.100	-	-	LDO	PTHR12758
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4470
SonicParanoid	1	1.000	-	-		X3853
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.110