DRSC/TRiP Functional Genomics Resources

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Protein Alignment Sgt and Tomm34

DIOPT Version :9

Sequence 1:NP_001246058.1 Gene:Sgt / 35052 FlyBaseID:FBgn0032640 Length:331 Species:Drosophila melanogaster
Sequence 2:NP_001278084.1 Gene:Tomm34 / 67145 MGIID:1914395 Length:309 Species:Mus musculus


Alignment Length:252 Identity:57/252 - (22%)
Similarity:107/252 - (42%) Gaps:60/252 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly     7 QSFVRSFIDY---LKKQGDVMSPDQTESIEVAIQCLQAAFD-LGDD-------VEAAPAAAGEEQ 60
            :.:..:::||   |:....|.|     ::|...:..:|..| ||.:       :...|.:|.:..
Mouse    99 EKYALAYVDYKTVLQIDNSVAS-----ALEGINRITRALMDSLGPEWRLKLPPIPVVPVSAQKRW 158

  Fly    61 ATTQSSS---TASAPDDDAVASGSAGIGAAAAAVPNNIDMFELFQSLYTERNPESLALAESIKNE 122
            .:..|.:   ||.....:|.|:.|        .||:..|:         ||       |:::|.|
Mouse   159 NSLPSDNHKETAKTKSKEATATKS--------RVPSAGDV---------ER-------AKALKEE 199

  Fly   123 GNRLMKENKYNEALLQYNRAIAFDPKNPIFYCNRAAAHIRLGENERAVTDCKSALVYNNNYSKAY 187
            ||.|:|:..:.:|:.:|:.::.........|.|||..|:.|.:.:.||.||..||..:....||:
Mouse   200 GNDLVKKGNHKKAIEKYSESLLCSSLESATYSNRALCHLVLKQYKEAVKDCTEALKLDGKNVKAF 264

  Fly   188 CRLGVAYSNMGNFEKAEQAYAKAIELEPDNEVYKSNLEAARNARNQPPQTGRLREDL 244
            .|...||..:.:::.:....:..:::||               ||.|.|  :||:::
Mouse   265 YRRAQAYKALKDYKSSLSDISSLLQIEP---------------RNGPAQ--KLRQEV 304

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SgtNP_001246058.1 SGTA_dimer 9..>48 CDD:293154 10/42 (24%)
TPR_11 116..177 CDD:290150 19/60 (32%)
TPR_2 116..149 CDD:285020 9/32 (28%)
TPR repeat 116..144 CDD:276809 9/27 (33%)
TPR_17 139..170 CDD:290167 7/30 (23%)
TPR repeat 149..179 CDD:276809 12/29 (41%)
TPR_16 156..218 CDD:290168 17/61 (28%)
TPR_1 184..217 CDD:278916 7/32 (22%)
TPR repeat 184..212 CDD:276809 5/27 (19%)
Tomm34NP_001278084.1 TPR 3 85..118 3/18 (17%)
TPR repeat 85..113 CDD:276809 2/13 (15%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 158..189 8/38 (21%)
TPR_11 192..257 CDD:290150 22/71 (31%)
TPR 4 193..226 9/32 (28%)
TPR repeat 193..221 CDD:276809 9/27 (33%)
TPR repeat 226..256 CDD:276809 12/29 (41%)
TPR 5 227..260 12/32 (38%)
TPR_1 229..260 CDD:278916 12/30 (40%)
TPR 6 261..294 7/47 (15%)
TPR 1 9..42
TPR repeat 9..37 CDD:276809
TPR_11 10..82 CDD:290150
TPR_11 50..115 CDD:290150 3/15 (20%)
TPR repeat 50..80 CDD:276809
TPR 2 51..84
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167846132
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.840

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