DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Sgt and sgta

DIOPT Version :9

Sequence 1:	NP_001246058.1	Gene:	Sgt / 35052	FlyBaseID:	FBgn0032640	Length:	331	Species:	Drosophila melanogaster
Sequence 2:	NP_001032333.1	Gene:	sgta / 394994	XenbaseID:	XB-GENE-962231	Length:	314	Species:	Xenopus tropicalis

Alignment Length:	358	Identity:	114/358 - (31%)
Similarity:	165/358 - (46%)	Gaps:	97/358 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 SFVRSFIDYLKKQGDVMSPDQTESIEVAIQCLQAAFDLG--DDVEAAPAAAGE--EQATTQSSST 68
            |.:|...|.|:..|  :|.|..||:|||||||:.||::.  |...|.|.:..|  .:||.|
Frog    10 SIIRHLHDQLRNGG--LSSDAQESLEVAIQCLETAFEVSIEDSNLAVPRSLQEIFTEATCQ---- 68

  Fly    69 ASAPDDDAVASGSAGIGAAAAAVPNNIDMFELFQSLYTERNP--ESLALAESIKNEGNRLMKENK 131
                |...|.||.|                          :|  |.:|.||.:|.|||..||...
Frog    69 ----DSPQVNSGLA--------------------------SPCDEDVAEAERLKTEGNEQMKLEN 103

  Fly   132 YNEALLQYNRAIAFDPKNPIFYCNRAAAHIRLGENERAVTDCKSALVYNNNYSKAYCRLGVAYSN 196
            :..|:..|::|:..:|.|.::|||||||:.:||....||.||:.|:..:.||||||.|:|:|.|:
Frog   104 FESAISYYSKALELNPTNAVYYCNRAAAYSKLGNYAGAVRDCEEAITIDPNYSKAYGRMGLALSS 168

  Fly   197 MGNFEKAEQAYAKAIELEPDNEVYKSNLEAARNARNQPPQ----TGRLREDLINMLSQP----MV 253
            :....:|...|.:|:.|:||||.|||||:.|.....:.|.    .|..  ||..:|:.|    |.
Frog   169 LNKHAEAVGFYKQALILDPDNETYKSNLKIAEQKMKELPSPMAAPGGF--DLAGLLNNPGFMSMA 231

  Fly   254 RNLFNNAEIDVEQLLSMLQNPMIMNTIRQQFGGGNAP-----------TLPNDMV---------- 297
            .||.||.:  |:||:|.:            ..||:.|           |.|||:.
Frog   232 SNLMNNPQ--VQQLMSGM------------ISGGHTPMAGAGAAAAGNTPPNDLASLIQAGQQFA 282

  Fly   298 --------QMIYNMTSQLTGFPNSNANPGNEQQ 322
                    ::|..:.||:...|.|:::  :|||
Frog   283 QQMQQQNPELIEQLRSQIRSRPPSSSH--DEQQ 313

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sgt	NP_001246058.1	SGTA_dimer	9..>48	CDD:293154	17/40 (43%)
		TPR_11	116..177	CDD:290150	26/60 (43%)
		TPR_2	116..149	CDD:285020	12/32 (38%)
		TPR repeat	116..144	CDD:276809	11/27 (41%)
		TPR_17	139..170	CDD:290167	13/30 (43%)
		TPR repeat	149..179	CDD:276809	15/29 (52%)
		TPR_16	156..218	CDD:290168	27/61 (44%)
		TPR_1	184..217	CDD:278916	13/32 (41%)
		TPR repeat	184..212	CDD:276809	11/27 (41%)
sgta	NP_001032333.1	SGTA_dimer	6..64	CDD:293154	22/55 (40%)
		TPR_11	87..153	CDD:290150	27/65 (42%)
		TPR repeat	88..116	CDD:276809	11/27 (41%)
		TPR_1	<95..121	CDD:278916	8/25 (32%)
		TPR_11	121..187	CDD:290150	29/65 (45%)
		TPR repeat	121..151	CDD:276809	15/29 (52%)
		TPR_1	122..155	CDD:278916	14/32 (44%)
		TPR_1	156..189	CDD:278916	13/32 (41%)
		TPR repeat	156..183	CDD:276809	10/26 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	141	1.000	Inparanoid score	I4377
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D501335at33208
OrthoFinder	1	1.000	-	-		FOG0002425
OrthoInspector	1	1.000	-	-		otm47568
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1333
SonicParanoid	1	1.000	-	-		X1609
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.090