DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Sgt and HIP-R

DIOPT Version :9

Sequence 1:	NP_001246058.1	Gene:	Sgt / 35052	FlyBaseID:	FBgn0032640	Length:	331	Species:	Drosophila melanogaster
Sequence 2:	NP_001014719.2	Gene:	HIP-R / 31335	FlyBaseID:	FBgn0029676	Length:	377	Species:	Drosophila melanogaster

Alignment Length:	362	Identity:	73/362 - (20%)
Similarity:	127/362 - (35%)	Gaps:	80/362 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPDAVQQSFVRSFIDYLKKQGDVMSPDQTESIEVAIQCLQAAFDLGDDVEA---APAAAGEEQAT 62
            ||   |..||:   |:::|.|..:.|.|........:|     ..|....|   .||.|.|:
  Fly    29 MP---QLQFVK---DFVEKFGGTVPPGQFNGGSAGGKC-----PFGGVAGAKANEPANAPED--- 79

  Fly    63 TQSSSTASAPDDDAVASGSAGIGAAAAAVPNNIDMFELFQSLYTERNPESLALAESIKNEGNRLM 127
            ::...:.|.|:.| |.....|:      :..:.|..:...:...:...|.:..|..::.:.....
  Fly    80 SEDEKSLSDPESD-VELDMEGV------IEADSDPAQPMGNYSKKATEEEVEQASELRAQAASAY 137

  Fly   128 KENKYNEALLQYNRAIAFDPKNPIFYCNRAAAHIRLGENERAVTDCKSALVYNNNYSKAYCRLGV 192
            .:.|::||:..|.:||...|.|.:|:..|..|.::|.:....:.||..||..|::.:..|...|.
  Fly   138 GQQKFDEAIALYTKAIELSPGNALFHAKRGQAFLKLKKPNACIRDCDVALELNSDLAAGYKFRGR 202

  Fly   193 AYSNMGNFEKAEQAYAKAIELEPDNEV-----------------------------YKSNLEAAR 228
            |...:|:||.|.....:|.:|:.|.|.                             .|......|
  Fly   203 ARRLLGDFELAAHDLRQACKLDFDEETDEWLKEVTPNAKKIEQHRLKQERRQAERKIKERQRDQR 267

  Fly   229 NARNQP------------------PQTGRLREDLINMLSQPMVRNLFNNAEIDVEQLLSMLQNPM 275
            .||.:.                  |..|.: .|::..:|.|.|.....:...:...:.....||.
  Fly   268 RARKEQEKHNASSGGSSGEFSGGNPGNGNM-SDILGAMSDPEVSAAIQDILSNPGNITKYASNPK 331

  Fly   276 IMNTIRQQFGGGNAPTLPNDMVQMIYNMTSQLTGFPN 312
            |.|.|::...||:        |...:....:..|.|:
  Fly   332 IYNLIKKIVPGGD--------VGAAFGQAGEKAGKPS 360

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sgt	NP_001246058.1	SGTA_dimer	9..>48	CDD:293154	9/38 (24%)
		TPR_11	116..177	CDD:290150	15/60 (25%)
		TPR_2	116..149	CDD:285020	8/32 (25%)
		TPR repeat	116..144	CDD:276809	6/27 (22%)
		TPR_17	139..170	CDD:290167	9/30 (30%)
		TPR repeat	149..179	CDD:276809	9/29 (31%)
		TPR_16	156..218	CDD:290168	18/61 (30%)
		TPR_1	184..217	CDD:278916	9/32 (28%)
		TPR repeat	184..212	CDD:276809	8/27 (30%)
HIP-R	NP_001014719.2	Hip_N	10..47	CDD:271228	8/23 (35%)
		TPR_11	125..190	CDD:290150	17/64 (27%)
		TPR_2	126..159	CDD:285020	8/32 (25%)
		TPR repeat	126..154	CDD:276809	6/27 (22%)
		TPR repeat	159..189	CDD:276809	9/29 (31%)
		TPR repeat	194..222	CDD:276809	8/27 (30%)
		STI1	299..336	CDD:128966	8/36 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462414
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840