DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Sgt and Stip1

DIOPT Version :10

Sequence 1:NP_609842.1 Gene:Sgt / 35052 FlyBaseID:FBgn0032640 Length:331 Species:Drosophila melanogaster
Sequence 2:NP_620266.1 Gene:Stip1 / 192277 RGDID:621599 Length:543 Species:Rattus norvegicus


Alignment Length:181 Identity:52/181 - (28%)
Similarity:89/181 - (49%) Gaps:10/181 - (5%)


- Green bases have known domain annotations that are detailed below.


  Fly   109 NPESLALAESIKNEGNRLMKENKYNEALLQYNRAIAFDPKNPIFYCNRAAAHIRLGENERAVTDC 173
            ||: |||.|  ||:||...::..|.:|:..|..||..:|::...|.||||.:.:|.|.:.|:.||
  Rat   356 NPD-LALEE--KNKGNECFQKGDYPQAMKHYTEAIKRNPRDAKLYSNRAACYTKLLEFQLALKDC 417

  Fly   174 KSALVYNNNYSKAYCRLGVAYSNMGNFEKAEQAYAKAIELEPD----NEVYKSNLEAARNARNQP 234
            :..:.....:.|.|.|...|...|.::.||...|.||::|:..    .:.|:..:.|..|..:.|
  Rat   418 EECIQLEPTFIKGYTRKAAALEAMKDYTKAMDVYQKALDLDSSCKEAADGYQRCMMAQYNRHDSP 482

  Fly   235 PQTGR---LREDLINMLSQPMVRNLFNNAEIDVEQLLSMLQNPMIMNTIRQ 282
            ....|   ...::..::|.|.:|.:....:.|.:.|...|:||:|...|::
  Rat   483 EDVKRRAMADPEVQQIMSDPAMRLILEQMQKDPQALSEHLKNPVIAQKIQK 533

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SgtNP_609842.1 SGTA_dimer 7..>48 CDD:465168
TPR 116..>233 CDD:440225 35/120 (29%)
TPR repeat 116..144 CDD:276809 9/27 (33%)
TPR repeat 149..179 CDD:276809 10/29 (34%)
TPR repeat 184..212 CDD:276809 10/27 (37%)
Stip1NP_620266.1 TPR 1 4..37
3a0801s09 <7..532 CDD:273380 51/178 (29%)
TPR repeat 7..32 CDD:276809
TPR repeat 37..67 CDD:276809
TPR 2 39..71
TPR repeat 72..100 CDD:276809
TPR 3 73..105
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 191..233
Bipartite nuclear localization signal. /evidence=ECO:0000255 222..239
TPR 4 225..258
TPR repeat 229..253 CDD:276809
TPR repeat 258..288 CDD:276809
TPR 5 260..292
TPR 6 300..333
TPR repeat 300..328 CDD:276809
TPR 7 360..393 13/34 (38%)
TPR repeat 364..388 CDD:276809 8/23 (35%)
TPR repeat 393..423 CDD:276809 10/29 (34%)
TPR 8 395..427 10/31 (32%)
TPR 9 428..461 11/32 (34%)
TPR repeat 428..456 CDD:276809 10/27 (37%)
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.