Protein Alignment BicD and BicD

DIOPT Version :10

• Sequence 1: NP_001260531.1
• Gene: BicD / 35051
• FlyBaseID: FBgn0000183
• Length: 802
• Species: Drosophila melanogaster
• Sequence 2: XP_554113.3
• Gene: BicD / 1279626
• VectorBaseID: AGAMI1_006445
• Length: 797
• Species: Anopheles gambiae
• Alignment Length: 792
• Identity: 577/792 - (72%)
• Similarity: 664/792 - (83%)
• Gaps: 24/792 - (3%)

  Fly    10 SADQSVQDLQMEVERLTRELDQVSSASAQSAQYGLSLLEEKSALQQKCEELETLYDNTRHELDIT 74
            ::...::.|:.|:||||||||||||.:.|||:|||.|||||..||.||||||:||:||:||||||
Mosquito     2 TSSAELETLRSEIERLTRELDQVSSENIQSAKYGLGLLEEKQNLQVKCEELESLYENTKHELDIT 66

  Fly    75 QEALTKFQTSQKVTNKTGIEQEDALLNESAARETSLNLQIFDLENELKQLRHELERVRNERDRML 139
            ||||.|||.:|:||.|:||||||||||||||.|||||:||.:||||.|||||||:||.:||||||
Mosquito    67 QEALQKFQKTQQVTTKSGIEQEDALLNESAAMETSLNMQIVELENETKQLRHELDRVTSERDRML 131

  Fly   140 QENSDFGRDKSDSEADRLRLKSELKDLKFRETRMLSEYSELEEENISLQKQVSSLRSSQVEFEGA 204
            |||::.|||||.:||:|.|||:||||:|:||.|||::||||||||||||||||||||||||||||
Mosquito   132 QENAEIGRDKSGTEAERARLKAELKDMKYREARMLADYSELEEENISLQKQVSSLRSSQVEFEGA 196

  Fly   205 KHEIRRLTEEVELLNQQVDELANLKKIAEKQMEEALETLQGEREAKYALKKELDGHLNRESMYHI 269
            ||||||||||:||||.||:|||:||||||||||:||..||.|||.|||||||||.|:||||||:|
Mosquito   197 KHEIRRLTEEIELLNSQVEELASLKKIAEKQMEDALTALQVERENKYALKKELDTHINRESMYNI 261

  Fly   270 SNLAYSIRSNMEDNASNNSDGEEE-----NLALKRLEADLSTE---LKSPDGTKCDLFSEIHLNE 326
            ||||||||| ||:||.|:||.|||     :..||||||.|..|   ||||||||.||||||||||
Mosquito   262 SNLAYSIRS-MEENALNSSDCEEEIPALRDSTLKRLEATLEAETADLKSPDGTKGDLFSEIHLNE 325

  Fly   327 LKKLEKQLESMESEKTHLTANLREAQTSLDKSQNELQNFMSRLALLAAHVDALVQLKKQIDVKEQ 391
            |||||||||:||:||..||||||:||.:||||||:|||||::|.|||||||||..|||||.::|.
Mosquito   326 LKKLEKQLETMETEKLCLTANLRDAQQNLDKSQNDLQNFMAKLMLLAAHVDALHTLKKQIQIEEN 390

  Fly   392 GKEGGQKKDELEQQLRALISQYANWFTLSAKEIDGLKTDIAELQKGLNYTDATTTLRNEVTNLKN 456
            ......|..::..:|...|.||::|||||:||||.||.|:||||||||.:||.|.||||:|||||
Mosquito   391 ITVSTAKDKDVNDKLNEAIMQYSSWFTLSSKEIDTLKADLAELQKGLNCSDAMTVLRNEITNLKN 455

  Fly   457 KLLATEQKSLDLQSDVQTLTHISQNAGQSLGSARSTLVALSDDLAQLYHLVCTVNGETPTRVLLD 521
            |||:.|||||||.||:|.||.:||.|||||.:.|:.|||||||||||||||||||||||.|||||
Mosquito   456 KLLSVEQKSLDLHSDIQVLTTLSQTAGQSLNTTRTNLVALSDDLAQLYHLVCTVNGETPNRVLLD 520

  Fly   522 HKTDDMSFENDSLTAIQSQFKSDVFIAKPQIVEDLQGLADSVEIKKYVDTVSDQIKYLKTAVEHT 586
            ||.||:|||||||||||||.|||:..:||.:.||||.|:|:|||:||||||||||:|||||||||
Mosquito   521 HKNDDLSFENDSLTAIQSQLKSDILTSKPHVFEDLQALSDAVEIRKYVDTVSDQIRYLKTAVEHT 585

  Fly   587 IDMNKHKI-----RSEGGDALEKVNTEEMEELQEQIVKLKSLLSVKREQIGTLRNVLKSNKQTAE 646
            |::||.|:     .:..||..|.  .||:.:|.|||:||:||||.|||||.|||.||||||.|||
Mosquito   586 IELNKDKVVTDSSATSSGDVKEA--KEEIADLHEQIIKLRSLLSTKREQIATLRTVLKSNKNTAE 648

  Fly   647 VALTNLKSKYENEKIIVSDTMSKLRNELRLLKEDAATFSSLRAMFAARCEEYVTQVDDLNRQLEA 711
            ||||||||||||||::|||||||||||||:|||||||||||||||||||||||||||:|..||.|
Mosquito   649 VALTNLKSKYENEKLVVSDTMSKLRNELRILKEDAATFSSLRAMFAARCEEYVTQVDELTHQLAA 713

  Fly   712 AEEEKKTLNQLLRLAVQQKLALTQRLEEMEMDREMRHVRRPMPAQR---GTSGKSSFS----TRP 769
            ||||||||||||||||||||.|||:|||:||||||||||||..:||   |..|||:||    .|.
Mosquito   714 AEEEKKTLNQLLRLAVQQKLGLTQKLEELEMDREMRHVRRPAASQRGGGGGGGKSAFSRGQPARN 778

  Fly   770 SSRNP-ASSNAN 780
            |.:|| ::||:|
Mosquito   779 SLQNPNSNSNSN 790

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
BicD	NP_001260531.1	SMC_prok_B	<10..138	CDD:274008	91/127 (72%)
		BicD	83..741	CDD:462863	500/670 (75%)
BicD	XP_554113.3	BicD	84..743	CDD:462863	505/671 (75%)