Protein Alignment BicD and zgc:171572

DIOPT Version :10

• Sequence 1: NP_001260531.1
• Gene: BicD / 35051
• FlyBaseID: FBgn0000183
• Length: 802
• Species: Drosophila melanogaster
• Sequence 2: XP_073767416.1
• Gene: zgc:171572 / 100330881
• ZFINID: ZDB-GENE-080219-47
• Length: 828
• Species: Danio rerio
• Alignment Length: 842
• Identity: 319/842 - (37%)
• Similarity: 486/842 - (57%)
• Gaps: 119/842 - (14%)

  Fly    21 EVERLTRELDQVSSASAQSAQYGLSLLEEKSALQQKCEELETLYDNTRHELDITQEALTKFQTSQ 85
            :||||:|||.:.:....|:|:|||::||:|..|:|:.:||:..|::.|.||:..:||..:..::.
Zfish     5 DVERLSRELAETTQEKIQAAEYGLAVLEDKQRLKQQYDELDAEYESVRRELEQLREAFGQAHSNH 69

  Fly    86 KVTNKTGIEQEDALLNESAARETSLNLQIFDLENELKQLRHELERVRNERDRM------LQENSD 144
            :.....|..:|::|:.|||.:|.....::.:|:.||:|.|..|..|::|.:|:      |:|||.
Zfish    70 RKVAADGESREESLIQESACKEAYYEQRMQELQAELRQTRTILTNVQSENERLATITQELRENSQ 134

  Fly   145 FGRDKSDSEADRLRLKSELKDLKFRETRMLSEYSELEEENISLQKQVSSLRSSQVEFEGAKHEIR 209
            .      .|..|.||:.::|:.||||.|:|.:|||||||||:|||.||.|:.|||||||.|||||
Zfish   135 M------VELQRSRLRDDIKEFKFRECRLLQDYSELEEENITLQKHVSVLKQSQVEFEGLKHEIR 193

  Fly   210 RLTEEVELLNQQVDELANLKKIAEKQMEEALETLQGEREAKYALKKELDGHLN-RESMYH----- 268
            ||.|:.:.||.|:::...||:|||:|:.|||||::.|||.|.||:|||..::: .:||||
Zfish   194 RLEEDTQFLNSQLEDAIRLKEIAERQLGEALETIKTEREQKAALRKELSQYMSISDSMYHSPLSI 258

  Fly   269 -ISNLAYSIRSNMEDN--------------ASNNSDGEEENLALKRLEADLSTELKSPDGTKCD- 317
             :..|.:|..:::|.|              .::|:|        .|:.....:||..|..:..|
Zfish   259 SLDGLKFSDDASIEPNNDEPLHVYENGFEKITDNND--------NRVSTPKKSELFQPSSSLVDN 315

  Fly   318 LFSEIHLNELKKLEKQLESMESEKTHLTANLREAQTSLDKSQNELQNFMSRLALLAAHVDALVQL 382
            |.:|::::|::||::||..:|.||..|.:.|:|:|..|:::...|.....::..|..:::|:.:|
Zfish   316 LLNELNISEIQKLKQQLLQVEREKVTLLSTLQESQKQLEQANGALSEEHEKVGRLTENLNAIRKL 380

  Fly   383 ---KKQIDVKEQGKEGGQKKDE------------LEQQLRALISQYANWFTLSAKEIDGLKTDIA 432
               |::....:..||....:|.            |:.:.:..:|:.:.    ..:|:..||.:.:
Zfish   381 QANKERQSALDNEKERDSHEDSEYYEVDINGPEILQCKYKVAVSEASQ----LKEELKTLKAEHS 441

  Fly   433 ELQKGLNYTDATTTLRNEVTNLKNKLLATEQKSLDLQSDV----QTLTHISQNAGQSLGS---AR 490
            ..|.  .|.:....|.::|.:|..:|.:.|:.|...:..:    :.|...|:.||:|.||   |:
Zfish   442 ACQS--QYQEERAQLESQVASLNAQLTSLERSSRSEREQLARLEKELRQASEVAGESQGSLNIAQ 504

  Fly   491 STLVALSDDLAQLYHLVCTVNGETPTRVLLDHKTDDMSFENDSL--------------------- 534
            ..|...|::||.|||.||..|.|||.|::||:..:..|..|.:.
Zfish   505 DELATFSEELANLYHHVCMCNNETPNRIMLDYYREGKSGVNGTQTNGWCSPDGRGRRSPILLTRG 569

  Fly   535 ---TAIQSQFKSDVFIAKPQIVEDLQGLADSVEIKKYVDTVSDQIKYLKTAVEHTIDMNKHKIRS 596
               ||..|...|....:.|..|.|.:  .:.:.|...|..:.|||::|:.||:.|.::::.::.|
Zfish   570 LFPTAESSDGTSSPISSIPSPVADPR--KEPMNIYNLVAIIRDQIRHLQLAVDRTTELSRQRMAS 632

  Fly   597 ----EGGDALEKVNTEEMEELQEQIVKLKSLLSVKREQIGTLRNVLKSNKQTAEVALTNLKSKYE 657
                .|.|       .|.|...|:|:|||||||.|||||.|||.|||:|||||||||.|||||||
Zfish   633 LELGLGAD-------REQEASVEEILKLKSLLSTKREQIATLRTVLKANKQTAEVALANLKSKYE 690

  Fly   658 NEKIIVSDTMSKLRNELRLLKEDAATFSSLRAMFAARCEEYVTQVDDLNRQLEAAEEEKKTLNQL 722
            |||.:|::||.||||||:.||||||||||||||||.||:|||||:|::.|||.|||:||||||.|
Zfish   691 NEKAMVTETMMKLRNELKALKEDAATFSSLRAMFATRCDEYVTQLDEMQRQLAAAEDEKKTLNSL 755

  Fly   723 LRLAVQQKLALTQRLEEMEMDREMRHVRRPMPAQRGTSGKSSFSTRP----SSRNPASSNAN 780
            ||:|:|||||||||||::|.|.|  .:|||     |.:|::. :|.|    |..:.:.|::|
Zfish   756 LRMAIQQKLALTQRLEDLEFDHE--QIRRP-----GANGRTR-NTAPRIKSSQTHVSRSDSN 809

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
BicD	NP_001260531.1	SMC_prok_B	<10..138	CDD:274008	40/116 (34%)
		BicD	83..741	CDD:462863	281/735 (38%)
zgc:171572	XP_073767416.1	None