DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18563 and prss60.1

DIOPT Version :9

Sequence 1:	NP_609841.2	Gene:	CG18563 / 35050	FlyBaseID:	FBgn0032639	Length:	379	Species:	Drosophila melanogaster
Sequence 2:	NP_001082915.1	Gene:	prss60.1 / 799770	ZFINID:	ZDB-GENE-070424-25	Length:	387	Species:	Danio rerio

Alignment Length:	245	Identity:	66/245 - (26%)
Similarity:	116/245 - (47%)	Gaps:	25/245 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   136 GGRCNTTGLYSWVVALFYEEVY---LTGGSLISPKVILTAAHNTMNKMNEDRIVVRAGEFVMNTT 197
            ||.....|.:.|.|:| :..:|   ..|||||:.:.:||||| .:.::....::|    |:..||
Zfish    36 GGVNAFDGSWPWQVSL-HSPIYGGHFCGGSLINSEWVLTAAH-CLPRITTSSLLV----FLGKTT 94

  Fly   198 NEPIQ-YE-ERVVERIVRHEGFIFQSGINNVALIFVKTPFVLNDRIGVLTLPSRQASF-EGRRCT 259
            .:.:. || .|.|..|..|..:...:..|::||:.:.:....::.|..:.|.::.:.| .|....
Zfish    95 QQGVNTYEINRTVSVITVHPSYNNLTNENDIALLHLSSAVTFSNYIRPVCLAAQNSVFPNGTSSW 159

  Fly   260 VAGW-DLVSSHDQSRMRIIKKLELTVLDRTTCVAQFRNTTLGRNFDLHPSLICA-RSEINRDFCF 322
            :.|| ::....:.....|:::..:.|:....|     |..||.. .:..::||| ..:..||.|.
Zfish   160 ITGWGNIQLGVNLPAPGILQETMIPVVPNDQC-----NALLGSG-SVTNNMICAGLLQGGRDTCQ 218

  Fly   323 GGGGYALFCSLGDENPHVFEQAGIVAWGMGCGLDL-PGIYTNVAMFRSWI 371
            |..|..:.    .:...|:.|:||.:||.||.... ||:||.|:.::|||
Zfish   219 GDSGGPMV----SKQCLVWVQSGITSWGYGCADPYSPGVYTRVSQYQSWI 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18563	NP_609841.2	Tryp_SPc	147..373	CDD:238113	63/234 (27%)
CG18563	NP_609841.2	Tryp_SPc	147..371	CDD:214473	61/232 (26%)
prss60.1	NP_001082915.1	Tryp_SPc	33..264	CDD:214473	64/243 (26%)
		Tryp_SPc	34..267	CDD:238113	66/245 (27%)
		Somatomedin_B	349..382	CDD:295334
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587595
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840