Protein Alignment CG18563 and TPSB2

DIOPT Version :10

• Sequence 1: NP_609841.2
• Gene: CG18563 / 35050
• FlyBaseID: FBgn0032639
• Length: 379
• Species: Drosophila melanogaster
• Sequence 2: NP_077078.5
• Gene: TPSB2 / 64499
• HGNCID: 14120
• Length: 275
• Species: Homo sapiens
• Alignment Length: 270
• Identity: 72/270 - (26%)
• Similarity: 125/270 - (46%)
• Gaps: 39/270 - (14%)

  Fly   127 PKPTERTQ----PGGRCNTTGLYSWVVALFYEEVY---LTGGSLISPKVILTAAHNTMNKMNEDR 184
            |.|.:..|    .||:......:.|.|:|...:.|   ..|||||.|:.:||||| .:....:|.
Human    20 PAPGQALQRVGIVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAH-CVGPDVKDL 83

  Fly   185 IVVRAGEFVMNTTNEPIQYEERV--VERIVRHEGFIFQSGINNVALIFVKTPFVLNDRIGVLTLP 247
            ..:|     :....:.:.|::::  |.||:.|..|.......::||:.::.|..::..:..:|||
Human    84 AALR-----VQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLP 143

  Fly   248 SRQASF-EGRRCTVAGWDLVSSHDQSRMRI-----IKKLELTVLDRTTCVAQFRNTTLGRNFD-- 304
            ....:| .|..|.|.||..|.:.:    |:     :|::::.:::...|.|::.   ||....
Human   144 PASETFPPGMPCWVTGWGDVDNDE----RLPPPFPLKQVKVPIMENHICDAKYH---LGAYTGDD 201

  Fly   305 ---LHPSLICARSEINRDFCFGGGGYALFCSLGDENPHVFEQAGIVAWGMGCGL-DLPGIYTNVA 365
               :...::|| ....||.|.|..|..|.|.:..    .:.|||:|:||.||.. :.|||||.|.
Human   202 VRIVRDDMLCA-GNTRRDSCQGDSGGPLVCKVNG----TWLQAGVVSWGEGCAQPNRPGIYTRVT 261

  Fly   366 MFRSWIYNRI 375
            .:..||::.:
Human   262 YYLDWIHHYV 271

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18563	NP_609841.2	Tryp_SPc	147..371	CDD:214473	65/240 (27%)
TPSB2	NP_077078.5	Tryp_SPc	31..268	CDD:238113	68/254 (27%)