Protein Alignment CG18563 and PRSS54

DIOPT Version :10

• Sequence 1: NP_609841.2
• Gene: CG18563 / 35050
• FlyBaseID: FBgn0032639
• Length: 379
• Species: Drosophila melanogaster
• Sequence 2: NP_001073961.1
• Gene: PRSS54 / 221191
• HGNCID: 26336
• Length: 395
• Species: Homo sapiens
• Alignment Length: 287
• Identity: 68/287 - (23%)
• Similarity: 108/287 - (37%)
• Gaps: 77/287 - (26%)

  Fly   118 TNDGAQAEQ----PKPTERTQPGGRCNTTGLYS-----WVVALFYEE-VYLTGGSLISPKVILTA 172
            |:.|.|...    |.|.|           ||.|     |||:|...: .:|..|.::|...:|:.
Human    28 TSCGVQKASVFYGPDPKE-----------GLVSSMEFPWVVSLQDSQYTHLAFGCILSEFWVLSI 81

  Fly   173 AHNTMNKMNEDRIVVRAGEFVMNTTNEPIQYEERVVERIVRHEGFIFQSGINNVALIFVKTPFVL 237
            |....|:.:   |||..|  :.|.....|.:.|..|..|:.||.|...|..||:||:...|....
Human    82 ASAIQNRKD---IVVIVG--ISNMDPSKIAHTEYPVNTIIIHEDFDNNSMSNNIALLKTDTAMHF 141

  Fly   238 NDRIGVLTLPSRQASFEGR---------RCTVAGWDLVS-SHDQSRMRIIKKLELTVLD------ 286
            .:.:       :...|.||         .|.|:||:..| :.:...|.:::|:.:..||
Human   142 GNLV-------QSICFLGRMLHTPPVLQNCWVSGWNPTSATGNHMTMSVLRKIFVKDLDMCPLYK 199

  Fly   287 --RTTCVAQFRNTTLGRNFDLHPSLICARSEINRDFCFGGGGYALFCSLGDENPHVFEQAGIVAW 349
              :|.|.:..:..|                   :..|.|..|..:.|.|...:..|..  |::.:
Human   200 LQKTECGSHTKEET-------------------KTACLGDPGSPMMCQLQQFDLWVLR--GVLNF 243

  Fly   350 GMGCGLDLPG--IYTNVAMFRSWIYNR 374
            |   |...||  :||.|..:..||.::
Human   244 G---GETCPGLFLYTKVEDYSKWITSK 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18563	NP_609841.2	Tryp_SPc	147..371	CDD:214473	57/244 (23%)
PRSS54	NP_001073961.1	Tryp_SPc	52..264	CDD:238113	57/247 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	324..348