DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment SPH93 and Prss41

DIOPT Version :9

Sequence 1:	NP_609840.1	Gene:	SPH93 / 35049	FlyBaseID:	FBgn0032638	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	XP_036016678.1	Gene:	Prss41 / 71003	MGIID:	1918253	Length:	353	Species:	Mus musculus

Alignment Length:	307	Identity:	95/307 - (30%)
Similarity:	147/307 - (47%)	Gaps:	62/307 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   217 GNPTTNVGSSE-------------LLSPSCGMSNANGLQMVEGITIDQARPAQYPWAVAIFHNGQ 268
            |:|..:.||.|             |||..||..|....::|.||...|.|   :||..::.....
Mouse    45 GSPYLHPGSREESQAADLKSTDIKLLSMPCGRRNDTRSRIVGGIESMQGR---WPWQASLRLKKS 106

  Fly   269 YLAGGSLIQPNVVLTVAH--------RVITIET-ELVVRAGDWDLKSDREIFLSEQREVERAVIH 324
            :..||||:....|||.||        ...|::. :|..:...|:.|:     .|.:..|:..:::
Mouse   107 HRCGGSLLSRRWVLTAAHCFRKYLDPEKWTVQLGQLTSKPSYWNRKA-----YSGRYRVKDIIVN 166

  Fly   325 EGFDFKSGANNLALLFLNSPFKLNDHIRTICL-PTPNKSFAGRRCTVAGWGKMRYEDQR-----Y 383
            .....||  ::||||.|.|....|..|:.:|: |:...|....||.|.|||.:: ||.:     |
Mouse   167 SEDKLKS--HDLALLRLASSVTYNKDIQPVCVQPSTFTSQHQPRCWVTGWGVLQ-EDLKPLPPPY 228

  Fly   384 STVLKKVQLLVVNRNVCEKFLRSTRLGAKFE-------LPKNIICAGGELG-RDTCTGDGGSALF 440
            .  |::||:.::|.:.|::.         ||       :.|::.|||.|.| .|||:||.|..|.
Mouse   229 H--LREVQVSILNNSRCQEL---------FEIFSLHHLITKDVFCAGAEDGSADTCSGDSGGPLV 282

  Fly   441 CSIGGENSGVYEQAGIVNWGVGCGQEGIPAIYTEVSKFTNWITEKLL 487
            |::    .|::.|.|||:||:|||:..:|.|||.||.:.|||...::
Mouse   283 CNM----DGLWYQIGIVSWGIGCGRPNLPGIYTNVSHYYNWIETMMI 325

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SPH93	NP_609840.1	GRP	<136..189	CDD:254089
		Tryp_SPc	250..485	CDD:238113	81/257 (32%)
		Tryp_SPc	252..482	CDD:214473	78/252 (31%)
Prss41	XP_036016678.1	Tryp_SPc	84..321	CDD:238113	83/262 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8716
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910