DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment SPH93 and zgc:123217

DIOPT Version :9

Sequence 1:	NP_609840.1	Gene:	SPH93 / 35049	FlyBaseID:	FBgn0032638	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	NP_001032480.1	Gene:	zgc:123217 / 641414	ZFINID:	ZDB-GENE-051113-188	Length:	326	Species:	Danio rerio

Alignment Length:	268	Identity:	77/268 - (28%)
Similarity:	122/268 - (45%)	Gaps:	43/268 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   233 CGMSNANGLQMVEGITIDQARPAQYPWAVAIFHNGQYLAGGSLIQPNVVLTVAHRVITIETELVV 297
            ||::..| .::|.|   ..|....:||.|:|.:|.:::.||:||....|:|.||.:|.....:
Zfish    28 CGVAPLN-TRIVGG---TDAPAGSWPWQVSIHYNNRHICGGTLIHSQWVMTAAHCIINTNINV-- 86

  Fly   298 RAGDWDLKSDREIFLSEQRE-------------VERAVIHEGFDFKSGANNLALLFLNSPFKLND 349
                |.|      :|..|.:             ::..:.|..|:.....|:::|:.|:.|...:.
Zfish    87 ----WTL------YLGRQTQSTSVANPNEVKVGIQSIIDHPSFNNSLLNNDISLMKLSQPVNFSL 141

  Fly   350 HIRTICLPTPNKSF-AGRRCTVAGWGKMRYEDQRYST--VLKKVQLLVVNRNVCEKFLRSTRLGA 411
            :||.|||...|..| .|..|...|||.:. :||....  .|::||:.||..::|.....|..
Zfish   142 YIRPICLAANNSIFYNGTSCWATGWGNIG-KDQALPAPQTLQQVQIPVVANSLCSTEYESVN--- 202

  Fly   412 KFELPKNIICAGGELGRDTCTGDGGSALFCSIGGENSGVYEQAGIVNWG--VGCGQEGIPAIYTE 474
            ...:...:||| |:..:.||.||.|....|..|    .|:.||||.::|  .||.....|.:|:.
Zfish   203 NATITPQMICA-GKANKGTCQGDSGGPFQCKQG----SVWIQAGITSYGTSAGCAVGAYPDVYSR 262

  Fly   475 VSKFTNWI 482
            ||:|.:||
Zfish   263 VSEFQSWI 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SPH93	NP_609840.1	GRP	<136..189	CDD:254089
		Tryp_SPc	250..485	CDD:238113	72/251 (29%)
		Tryp_SPc	252..482	CDD:214473	70/247 (28%)
zgc:123217	NP_001032480.1	Tryp_SPc	36..270	CDD:214473	72/257 (28%)
zgc:123217	NP_001032480.1	Tryp_SPc	37..273	CDD:238113	74/258 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910