DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SPH93 and si:dkeyp-93a5.3

DIOPT Version :9

Sequence 1:	NP_609840.1	Gene:	SPH93 / 35049	FlyBaseID:	FBgn0032638	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	XP_021326347.1	Gene:	si:dkeyp-93a5.3 / 571565	ZFINID:	ZDB-GENE-131127-100	Length:	328	Species:	Danio rerio

Alignment Length:	293	Identity:	83/293 - (28%)
Similarity:	127/293 - (43%)	Gaps:	59/293 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   233 CGMSNAN-GLQMVEGITIDQARPAQYPWAVAIFHNGQY--LAGGSLIQPNVVLTVAHRVI-TIET 293
            ||..|.. ..::|.|:   .|....:||.|::  .|:|  ..|||||....|||.||.:: ...:
Zfish    25 CGRPNPTLNPRIVGGV---NATHGAWPWMVSL--QGRYGHFCGGSLINNQWVLTAAHCIVDQTPS 84

  Fly   294 ELVVRAGDW-----DLKSDREIFLSEQREVERAVIHEGFDFKSGANNLALLFLNSPFKLNDHIRT 353
            .::|..|.|     |:.       |..|.:...:.|..:...:..|::|||.|.|..:..|:|:.
Zfish    85 SIIVYLGKWRSYVADVN-------SISRTIRHIIPHPSYSNITKDNDIALLQLTSTVQYTDYIKP 142

  Fly   354 ICLPTPNKSF-AGRRCTVAGWGKMRY-------------EDQRYSTVLKKVQLLVVNRNVCEKFL 404
            |||...|.:| .|....|||||.:..             ....:..:|::.:|.|.:...|....
Zfish   143 ICLADENSNFPRGTNSWVAGWGDIGVLGTGGIRGRTTVSVPLPHPGILQEAELKVYSNADCNNIC 207

  Fly   405 RSTRLGAKFELPKNIICAGGEL-GRDTCTGDGGSALF--CSIGGENSGVYEQAGIVNWGVGCGQE 466
            ..       .:..|:||||... |:.|.:||.|..|.  ||       |:.|||:::.|.||.|.
Zfish   208 HG-------RITPNMICAGTRPGGKATFSGDSGGPLMTKCS-------VWVQAGVLSHGYGCAQP 258

  Fly   467 GIPAIYTEVSKFTNWITEKL---LP----FDYR 492
            .:|.::..||::..|||..:   ||    ||.|
Zfish   259 NLPEVFIRVSEYKQWITGNVGGNLPGFVLFDPR 291

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SPH93	NP_609840.1	GRP	<136..189	CDD:254089
		Tryp_SPc	250..485	CDD:238113	73/259 (28%)
		Tryp_SPc	252..482	CDD:214473	70/254 (28%)
si:dkeyp-93a5.3	XP_021326347.1	Tryp_SPc	36..274	CDD:238113	72/263 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910