DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SPH93 and zgc:112038

DIOPT Version :9

Sequence 1:	NP_609840.1	Gene:	SPH93 / 35049	FlyBaseID:	FBgn0032638	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	NP_001018482.1	Gene:	zgc:112038 / 553673	ZFINID:	ZDB-GENE-050522-271	Length:	311	Species:	Danio rerio

Alignment Length:	272	Identity:	86/272 - (31%)
Similarity:	130/272 - (47%)	Gaps:	49/272 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   233 CG---MSNANGLQMVEGITIDQARPAQYPWAVAIFHNG--QYLAGGSLIQPNVVLTVAHRVITIE 292
            ||   ::|.||     |   |.|....:||..:|....  .::.|||||..:.||:.||..:...
Zfish    27 CGQAPLNNNNG-----G---DDAVAGSWPWQASIHRISPEDHICGGSLINKDWVLSAAHCFMITA 83

  Fly   293 TELVVRAGDWDLKSDREIFLSEQ-----------REVERAVIHEGFDFKSGANNLALLFLNSPFK 346
            |            ::.:|||..|           |.:.:.|||..:...:..|::|||.|:|...
Zfish    84 T------------ANIKIFLGRQFQTGSNPNEISRTLTQIVIHPDYSTTTQNNDIALLRLSSSVT 136

  Fly   347 LNDHIRTICLPTPNKSFA-GRRCTVAGWGKMRYEDQRYSTVLKKVQLLVVNRNVCEKFLRSTRLG 410
            ..|:||.:||.:.:..|| |.:..:.||.|.|..|.:.:.||::|||.||:...|....:..
Zfish   137 FTDYIRPVCLASADSVFAGGTKSWITGWDKHRSSDIQVTNVLQEVQLPVVSNTECNADYKGI--- 198

  Fly   411 AKFELPKNIICAG-GELGRDTCTGDGGSALFCSIGGENSGVYEQAGIVNWGVGCGQEGIPAIYTE 474
                :..|:|||| .|.|:|.|.||.|..:.    .:|...:.|:|||::|..||....|.|||.
Zfish   199 ----ITDNMICAGINEGGKDACQGDSGGPMV----SQNGSRWIQSGIVSFGRECGLPRYPGIYTR 255

  Fly   475 VSKFTNWITEKL 486
            ||::.:|||.:|
Zfish   256 VSQYQSWITSEL 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SPH93	NP_609840.1	GRP	<136..189	CDD:254089
		Tryp_SPc	250..485	CDD:238113	79/249 (32%)
		Tryp_SPc	252..482	CDD:214473	75/244 (31%)
zgc:112038	NP_001018482.1	Tryp_SPc	37..263	CDD:214473	78/256 (30%)
zgc:112038	NP_001018482.1	Tryp_SPc	37..263	CDD:238113	78/256 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587523
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840