DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SPH93 and prss27

DIOPT Version :9

Sequence 1:	NP_609840.1	Gene:	SPH93 / 35049	FlyBaseID:	FBgn0032638	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	XP_031749235.1	Gene:	prss27 / 496619	XenbaseID:	XB-GENE-5744470	Length:	724	Species:	Xenopus tropicalis

Alignment Length:	276	Identity:	84/276 - (30%)
Similarity:	140/276 - (50%)	Gaps:	37/276 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   229 LSPSCGMSNANGLQMVEGITIDQARPAQYPWAVAIFHNGQYLAGGSLIQPNVVLTVAH---RVIT 290
            :|..||.. |...::|.|   :.|...::||.|:|.:...::.||||:..|.|::.||   |...
Frog   407 ISTGCGQP-AFSDRIVGG---NNAVFGEWPWQVSIVYQNSHICGGSLVSSNWVVSAAHCFPRSYK 467

  Fly   291 IETELVVRAGDW---DLKSDREIFLSEQREVERAVIHEGFDFKSGANNLALLFLNSPFKLNDHIR 352
            || .:.|..|.:   :|.||..|.     .|:|.:.:..:..:..:.::|::.:.||...:.:|.
Frog   468 IE-NMQVLLGCFALMNLTSDAVII-----RVKRVITYPLYTGEGSSGDIAMVEMESPVTYSSYIL 526

  Fly   353 TICLPTPNKSF-AGRRCTVAGWGKMRYEDQRYST--VLKKVQLLVVNRNVCEKFLR-------ST 407
            .||:|..|:.| :|:.|.|.|||.:: .|...|.  .|::|::.:||.:.|:....       :|
Frog   527 PICIPLTNEDFPSGKMCWVTGWGNIQ-SDVSLSPPYPLQEVEVPLVNASSCDTMYHYNSDLNPAT 590

  Fly   408 RLGAKFELPKNIICAGGELG-RDTCTGDGGSALFCSIGGENSGVYEQAGIVNWGVGCGQEGIPAI 471
            :|     :..::||||...| :|.|.||.|..|.|..|    ..:...|||:||.||.|...|.:
Frog   591 QL-----VHDDMICAGYPEGQKDACQGDSGGPLACKSG----NYWFLTGIVSWGDGCAQPNRPGV 646

  Fly   472 YTEVSKFTNWITEKLL 487
            ||:||.|::||.:.|:
Frog   647 YTKVSSFSSWINQYLV 662

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SPH93	NP_609840.1	GRP	<136..189	CDD:254089
		Tryp_SPc	250..485	CDD:238113	77/251 (31%)
		Tryp_SPc	252..482	CDD:214473	75/246 (30%)
prss27	XP_031749235.1	Tryp_SPc	34..271	CDD:238113
prss27	XP_031749235.1	Tryp_SPc	420..659	CDD:238113	79/257 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910