DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SPH93 and CG3916

DIOPT Version :9

Sequence 1:	NP_609840.1	Gene:	SPH93 / 35049	FlyBaseID:	FBgn0032638	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	NP_650167.1	Gene:	CG3916 / 41484	FlyBaseID:	FBgn0038003	Length:	267	Species:	Drosophila melanogaster

Alignment Length:	274	Identity:	69/274 - (25%)
Similarity:	115/274 - (41%)	Gaps:	44/274 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   222 NVGSSELLSPSCGMSNANGLQMVEGITIDQARPAQYPWAVAIFHNGQYLAGGSLIQPNVVLTVAH 286
            :|.:|...||    :..||     |..:::..|.|....:......|:..|||::....|||.||
  Fly    19 DVVTSTTESP----TRING-----GQRVNETVPFQVSLQMQRRGRWQHFCGGSIVSGQHVLTAAH 74

  Fly   287 RVITIETE---LVVRAGDWDLKSDREIFLSEQREVERAVIHEGFDFKSG-ANNLALLFLNSPFKL 347
            .:..::.|   :||...:|.....|...:::.       :|..:..... .|::||:.:..||:|
  Fly    75 CMEKMKVEDVSVVVGTLNWKAGGLRHRLVTKH-------VHPQYSMNPRIINDIALVKVTPPFRL 132

  Fly   348 -NDHIRTICLPTPNKSFAGRRCTV--AGWGKMRYEDQRYSTVLKKVQLL----VVNRNVCEKFLR 405
             ...|.||.:...::  .|.:..|  .|||... .....:|:..::|.|    :.|.:..:|..|
  Fly   133 ERSDISTILIGGSDR--IGEKVPVRLTGWGSTS-PSTSSATLPDQLQALNYRTISNEDCNQKGFR 194

  Fly   406 STRLGAKFELPKNIICAGGELGRDTCTGDGGSALFCSIGGENSGVYEQAGIVNWGVGCGQEGIPA 470
            .||         |.|||....|:..|.||.|..|...  |:...:   .|||::|.....:|.|.
  Fly   195 VTR---------NEICALAVQGQGACVGDSGGPLIRP--GKQPHL---VGIVSYGSSTCAQGRPD 245

  Fly   471 IYTEVSKFTNWITE 484
            :||.||.|..:|::
  Fly   246 VYTRVSSFLPYISQ 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SPH93	NP_609840.1	GRP	<136..189	CDD:254089
		Tryp_SPc	250..485	CDD:238113	62/246 (25%)
		Tryp_SPc	252..482	CDD:214473	61/240 (25%)
CG3916	NP_650167.1	Tryp_SPc	30..257	CDD:214473	64/255 (25%)
CG3916	NP_650167.1	Tryp_SPc	31..260	CDD:238113	65/258 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24256
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010