DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SPH93 and CG17404

DIOPT Version :9

Sequence 1:	NP_609840.1	Gene:	SPH93 / 35049	FlyBaseID:	FBgn0032638	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	NP_650165.2	Gene:	CG17404 / 41482	FlyBaseID:	FBgn0038001	Length:	275	Species:	Drosophila melanogaster

Alignment Length:	248	Identity:	74/248 - (29%)
Similarity:	113/248 - (45%)	Gaps:	40/248 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   254 PAQY-PWAVAIFH---NGQ-YLAGGSLIQPNVVLTVAHRVITIE-TELVVRAGDWDL--KSDREI 310
            |.:: |:.|::.:   .|| :..|||:|.||.:||.||....:. :.:.|.||...|  |..|..
  Fly    43 PGEHVPYQVSLQYRTRGGQMHFCGGSIIAPNRILTAAHCCQGLNASRMSVVAGIRGLNEKGSRSQ 107

  Fly   311 FLSEQREVERAVIHEGFDFKSGANNLALLFLNSPFKLNDH-IRTICLPTPNKSFAGR--RCTVAG 372
            .||..       ||..:. :...::||:|.:..|.|||:. |..|...:..|.|.|.  ..|:.|
  Fly   108 VLSYS-------IHPKYQ-ELVTSDLAVLSIKPPLKLNNSTISAIEYRSQGKDFVGGGVPVTLTG 164

  Fly   373 WGKMR-------YEDQRYSTVLKKVQLLVVNRNVCEKFLRSTRLGAKFELPKNIICAGGELGRDT 430
            || :|       .::..|..||:::....::.:.|       |......:....|||.|.. |..
  Fly   165 WG-LRLPVPFPFLDNVNYPNVLQRMSYHTISNSEC-------RNAGMESVTDTEICARGPF-RGA 220

  Fly   431 CTGDGGSALFCSIGGENSGVYEQAGIVNWG-VGCGQEGIPAIYTEVSKFTNWI 482
            |:||.|..|..    |:....:|.|||::| |.||....|.:||.||.|::||
  Fly   221 CSGDSGGPLVM----ESKNGLQQVGIVSYGLVVCGLYISPDVYTRVSTFSDWI 269

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SPH93	NP_609840.1	GRP	<136..189	CDD:254089
		Tryp_SPc	250..485	CDD:238113	74/248 (30%)
		Tryp_SPc	252..482	CDD:214473	72/246 (29%)
CG17404	NP_650165.2	Tryp_SPc	34..269	CDD:214473	72/246 (29%)
CG17404	NP_650165.2	Tryp_SPc	35..269	CDD:238113	72/246 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24256
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100