DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SPH93 and CG9372

DIOPT Version :9

Sequence 1:	NP_609840.1	Gene:	SPH93 / 35049	FlyBaseID:	FBgn0032638	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	NP_649132.1	Gene:	CG9372 / 40137	FlyBaseID:	FBgn0036891	Length:	408	Species:	Drosophila melanogaster

Alignment Length:	289	Identity:	83/289 - (28%)
Similarity:	139/289 - (48%)	Gaps:	34/289 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   206 TTNFGNP---TNNGGNPTTNVGSSELLSPSCGMSNANGLQMVEGITIDQARPAQYPWAVAIFHNG 267
            |:|..:|   |:..|:....|...|  ...||:::....::..|   ..|.|.::||..|:...|
  Fly   136 TSNRFSPQVVTSADGDEPRIVNKPE--QRGCGITSRQFPRLTGG---RPAEPDEWPWMAALLQEG 195

  Fly   268 Q--YLAGGSLIQPNVVLTVAHRVITIETE-LVVRAGDWDLKSDREIFLSEQR----EVERAVIHE 325
            .  ...||.||....|||.||.:.....| :.||.|:::..     .|:|.|    .:...|:|.
  Fly   196 LPFVWCGGVLITDRHVLTAAHCIYKKNKEDIFVRLGEYNTH-----MLNETRARDFRIANMVLHI 255

  Fly   326 GFDFKSGANNLALLFLNSPFKLNDHIRTICLPTPNKSFAGRRCTVAGWGKMRYEDQRYSTVLKKV 390
            .::.::..|::|::.::.....|.:|..:|:|..|:.::.|...|.|||..::... :|.:|.:|
  Fly   256 DYNPQNYDNDIAIVRIDRATIFNTYIWPVCMPPVNEDWSDRNAIVTGWGTQKFGGP-HSNILMEV 319

  Fly   391 QLLVVNRNVC-EKFLRSTRLGAKFELPKNIICAG-GELGRDTCTGDGGSALFCSIGGENSGVYEQ 453
            .|.|..::.| ..|::        .:|...:||| .|.|:|:|.||.|..|...:..:.   :..
  Fly   320 NLPVWKQSDCRSSFVQ--------HVPDTAMCAGFPEGGQDSCQGDSGGPLLVQLPNQR---WVT 373

  Fly   454 AGIVNWGVGCGQEGIPAIYTEVSKFTNWI 482
            .|||:|||||||.|.|.|||.|.::.:||
  Fly   374 IGIVSWGVGCGQRGRPGIYTRVDRYLDWI 402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SPH93	NP_609840.1	GRP	<136..189	CDD:254089
		Tryp_SPc	250..485	CDD:238113	73/242 (30%)
		Tryp_SPc	252..482	CDD:214473	71/238 (30%)
CG9372	NP_649132.1	CLIP	87..132	CDD:197829
		Tryp_SPc	173..402	CDD:214473	72/248 (29%)
		Tryp_SPc	176..402	CDD:238113	72/245 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457555
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840