DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment SPH93 and CG6462

DIOPT Version :9

Sequence 1:	NP_609840.1	Gene:	SPH93 / 35049	FlyBaseID:	FBgn0032638	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	NP_648011.1	Gene:	CG6462 / 38681	FlyBaseID:	FBgn0035663	Length:	319	Species:	Drosophila melanogaster

Alignment Length:	300	Identity:	68/300 - (22%)
Similarity:	117/300 - (39%)	Gaps:	83/300 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   217 GNPT----TNVGSSELLSPSCGMSNANGLQMVEGITIDQARPAQYPWAV--AIFHNGQYL--AGG 273
            ||.|    |.:...||                       |....:|:.|  .|..:|..|  .||
  Fly    67 GNQTAAVRTRIAGGEL-----------------------ATRGMFPYQVGLVIQLSGADLVKCGG 108

  Fly   274 SLIQPNVVLTVAHRVITIETELVVRAGDWDLKSDREIFLSEQREVER-AVIHEGF----DFK--S 331
            |||....|||.||.:    |:.:..    .:.:...:|...:..||. .|.|..|    |:.  .
  Fly   109 SLITLQFVLTAAHCL----TDAIAA----KIYTGATVFADVEDSVEELQVTHRDFIIYPDYLGFG 165

  Fly   332 GANNLALLFLNSPFKLNDHIRTICLPTP--NKSF-AGRRCTVAGWGKMRYEDQRYSTVLKKVQLL 393
            |.::|||:.|....:.::.::.|.|...  :::| .|:..|::|||.:.....:.:.:|:.:...
  Fly   166 GYSDLALIRLPRKVRTSEQVQPIELAGEFMHQNFLVGKVVTLSGWGYLGDSTDKRTRLLQYLDAE 230

  Fly   394 VVNRNVCEKFLRSTRLGAKFELP-----KNIICAGGELGRDTCTGDGGSALFCSIGGENSGVYE- 452
            |:::..|..:.          ||     :..:|..|..||..|.||.|..:          ||.
  Fly   231 VIDQERCICYF----------LPGLVSQRRHLCTDGSNGRGACNGDSGGPV----------VYHW 275

  Fly   453 -----QAGIVNWG--VGCGQEGIPAIYTEVSKFTNWITEK 485
                 ..|:.::|  .|| :.|.|.:||.::.:..||.::
  Fly   276 RNVSYLIGVTSFGSAEGC-EVGGPTVYTRITAYLPWIRQQ 314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SPH93	NP_609840.1	GRP	<136..189	CDD:254089
		Tryp_SPc	250..485	CDD:238113	62/261 (24%)
		Tryp_SPc	252..482	CDD:214473	60/256 (23%)
CG6462	NP_648011.1	Tryp_SPc	76..311	CDD:214473	62/286 (22%)
CG6462	NP_648011.1	Tryp_SPc	77..314	CDD:238113	64/288 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457620
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930