DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SPH93 and tpr

DIOPT Version :9

Sequence 1:	NP_609840.1	Gene:	SPH93 / 35049	FlyBaseID:	FBgn0032638	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	NP_611611.1	Gene:	tpr / 37486	FlyBaseID:	FBgn0034661	Length:	372	Species:	Drosophila melanogaster

Alignment Length:	296	Identity:	84/296 - (28%)
Similarity:	146/296 - (49%)	Gaps:	27/296 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   192 TTNVGNPTNNGGNPTTNFG-NPTNNGGNPTTNVGSSELLSPSCGMSNANGLQMVEGITIDQARPA 255
            ||:...|..:....||... .|.....||..|....     .||::|.. .::|.|   .:....
  Fly    81 TTSTTTPAPSSSTTTTRRATTPAPPTLNPPRNCSDC-----VCGIANIQ-KRIVGG---QETEVH 136

  Fly   256 QYPWAVAIFHNGQYLAGGSLIQPNVVLTVAHRVITIETELV-VRAGDWDLKSDREIFLSEQ--RE 317
            ||||...:.:.|::....||:....:||.:|.|.....|.: ||.    |:.||::...::  |:
  Fly   137 QYPWVAMLLYGGRFYCAASLLNDQFLLTASHCVYGFRKERISVRL----LEHDRKMSHMQKIDRK 197

  Fly   318 VERAVIHEGFDFKSGANNLALLFLNSPFKLNDHIRTICLPTPNKSFAGRRCTVAGWGKMRYEDQR 382
            |...:.|..::.::..|::|::.|:.|.:.|:.:..:|:|||.:||.|....|.|||.::.....
  Fly   198 VAEVITHPKYNARNYDNDIAIIKLDEPVEFNEVLHPVCMPTPGRSFKGENGIVTGWGALKVGGPT 262

  Fly   383 YSTVLKKVQLLVVNRNVCEKFLRSTRLGAKFELPKNIICAG-GELGRDTCTGDGGSALFCSIGGE 446
             |..|::||:.:::::.|    |.:|.|.|  :..|::|.| .|.|:|:|.||.|..|.....|.
  Fly   263 -SDTLQEVQVPILSQDEC----RKSRYGNK--ITDNMLCGGYDEGGKDSCQGDSGGPLHIVASGT 320

  Fly   447 NSGVYEQAGIVNWGVGCGQEGIPAIYTEVSKFTNWI 482
            ..  ::.||:|:||.||.:.|.|.:|..|:::..||
  Fly   321 RE--HQIAGVVSWGEGCAKAGYPGVYARVNRYGTWI 354

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SPH93	NP_609840.1	GRP	<136..189	CDD:254089
		Tryp_SPc	250..485	CDD:238113	70/237 (30%)
		Tryp_SPc	252..482	CDD:214473	68/233 (29%)
tpr	NP_611611.1	Tryp_SPc	126..354	CDD:214473	70/243 (29%)
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	72/244 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457687
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24256
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940