DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SPH93 and Prss33

DIOPT Version :9

Sequence 1:	NP_609840.1	Gene:	SPH93 / 35049	FlyBaseID:	FBgn0032638	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	XP_017173005.1	Gene:	Prss33 / 353130	MGIID:	2661234	Length:	341	Species:	Mus musculus

Alignment Length:	273	Identity:	83/273 - (30%)
Similarity:	128/273 - (46%)	Gaps:	39/273 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   232 SCGMSNANGLQMVEGITIDQARPAQYPWAVAIFHNGQYLAGGSLIQPNVVLTVAH----RVITIE 292
            :||....:. ::|.|   ..|:..::||..:|.|.|.::.|||||.|..|||..|    ||...|
Mouse    88 ACGQPRMSS-RIVGG---RDAQDGEWPWQTSIQHRGAHVCGGSLIAPQWVLTAGHCFPRRVWPSE 148

  Fly   293 TELVVRAGDWDLKSDREIFLSEQREVERAVIHEGFDFKSGANNLALLFLNSPFKLNDHIRTICLP 357
            ..:::.|...|::|..|:.:    .|.|.::...:.......:||||.|..|..|:..|:.:|||
Mouse   149 YSVLLGALSLDVRSSHELLV----PVLRVLLPPDYSEDEARGDLALLQLRHPVSLSTRIQPVCLP 209

  Fly   358 TP-NKSFAGRRCTVAGWG---------KMRYEDQRYSTVLKKVQLLVVNRNVCEKFLR---STRL 409
            .| :....|..|.|.|||         |.|        .|:.|::.:::...|::...   :...
Mouse   210 APGSHPPPGSPCWVTGWGSLSPGVPLPKGR--------PLQGVRVPLLDSRACDRLYHVGANVPQ 266

  Fly   410 GAKFELPKNIICAGGELG-RDTCTGDGGSALFCSIGGENSGVYEQAGIVNWGVGCGQEGIPAIYT 473
            |.:..||.| :|||...| :|.|.||.|..|.|.    .||.:...|:|:||.||.....|.:||
Mouse   267 GERIVLPGN-LCAGYRRGHKDACQGDSGGPLTCM----ESGHWVLVGVVSWGKGCALPNRPGVYT 326

  Fly   474 EVSKFTNWITEKL 486
            .|:|::.||..:|
Mouse   327 NVAKYSPWIQARL 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SPH93	NP_609840.1	GRP	<136..189	CDD:254089
		Tryp_SPc	250..485	CDD:238113	78/252 (31%)
		Tryp_SPc	252..482	CDD:214473	76/247 (31%)
Prss33	XP_017173005.1	Tryp_SPc	98..336	CDD:238113	79/257 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8716
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000