DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SPH93 and CG4793

DIOPT Version :9

Sequence 1:	NP_609840.1	Gene:	SPH93 / 35049	FlyBaseID:	FBgn0032638	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	NP_723941.2	Gene:	CG4793 / 34941	FlyBaseID:	FBgn0028514	Length:	910	Species:	Drosophila melanogaster

Alignment Length:	310	Identity:	123/310 - (39%)
Similarity:	169/310 - (54%)	Gaps:	33/310 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   195 VGNPTNNGGNPTTNFGNPTNNGGN---------PTTNV------GSSELLSPSCGMSNANGLQMV 244
            :|..|   |.|..:| ...|||..         |.|.:      ..::.|...||..|..|:
  Fly    37 IGTET---GRPIIDF-RGLNNGNQGCESGQTCCPKTEILQYPVQADNQPLPTECGHVNRIGV--- 94

  Fly   245 EGITI----DQARPAQYPWAVAIFHNGQY--LAGGSLIQPNVVLTVAHRVITI-ETELVVRAGDW 302
             |.||    |.|:..:.||.||:..:...  |.|||||..:||||.:.:.:.: |..|:||||:|
  Fly    95 -GFTITNARDIAQKGELPWMVALLDSRSRLPLGGGSLITRDVVLTSSTKTLEVPEKYLIVRAGEW 158

  Fly   303 DLKSDREIFLSEQREVERAVIHEGFDFKSGANNLALLFLNSPFKLNDHIRTICLPTPNKSFAGRR 367
            |.:|..|....|...:.:.|.|.....::||||.|||||..|.||:.||..||||.||::|...|
  Fly   159 DFESITEERAHEDVAIRKIVRHTNLSVENGANNAALLFLARPLKLDHHIGLICLPPPNRNFIHNR 223

  Fly   368 CTVAGWGKMRYEDQRYSTVLKKVQLLVVNRNVCEKFLRSTRLGAKFELPKNIICAGGELGRDTCT 432
            |.|:||||....|..|..:|||::|.:|:|:||:..|:.. .|..|.|..::||||||.|:|||.
  Fly   224 CIVSGWGKKTALDNSYMNILKKIELPLVDRSVCQTKLQGP-YGKDFILDNSLICAGGEPGKDTCK 287

  Fly   433 GDGGSALFCSIGGENSGVYEQAGIVNWGVGCGQEGIPAIYTEVSKFTNWI 482
            ||||:.|.|.:..:.:. ||..||||:|.|||.. :||.||:||:..:||
  Fly   288 GDGGAPLACPLQSDPNR-YELLGIVNFGFGCGGP-LPAAYTDVSQIRSWI 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SPH93	NP_609840.1	GRP	<136..189	CDD:254089
		Tryp_SPc	250..485	CDD:238113	105/236 (44%)
		Tryp_SPc	252..482	CDD:214473	102/232 (44%)
CG4793	NP_723941.2	Tryp_SPc	105..337	CDD:238113	104/234 (44%)
CG4793	NP_723941.2	Tryp_SPc	105..335	CDD:214473	102/232 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471547
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BM7R
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003848
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24256
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.840