DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment SPH93 and prss60.3

DIOPT Version :9

Sequence 1:	NP_609840.1	Gene:	SPH93 / 35049	FlyBaseID:	FBgn0032638	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	XP_002662541.2	Gene:	prss60.3 / 335152	ZFINID:	ZDB-GENE-030131-7092	Length:	330	Species:	Danio rerio

Alignment Length:	265	Identity:	85/265 - (32%)
Similarity:	136/265 - (51%)	Gaps:	32/265 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   233 CGMSNANGLQMVEGITIDQARPAQYPWAVAIFHN---GQYLAGGSLIQPNVVLTVAHRVITI-ET 293
            ||.:..| .::|.|:   .|.|..:||.|:: |:   |.:..|||||....|||.||.:..: ||
Zfish    27 CGQAPLN-TRIVGGV---NASPGSWPWQVSL-HSPKYGGHFCGGSLISSEWVLTAAHCLSGVSET 86

  Fly   294 ELVVRAGDWDLKSDREIFLSE-QREVERAVIHEGFDFKSGANNLALLFLNSPFKLNDHIRTICLP 357
            .|||..|   .::.:.|.:.| .|.|.::.:|..::..:..|::|||.|:|.....::||.:||.
Zfish    87 TLVVYLG---RRTQQGINIYETSRNVAKSFVHSSYNSNTNDNDIALLRLSSAVTFTNYIRPVCLA 148

  Fly   358 TPNKSF-AGRRCTVAGWGKMRY-EDQRYSTVLKKVQLLVVNRNVCEKFLRSTRLGAKFELPKNII 420
            ..|..: ||....:.|||.::. .:.....:|::..:.||..:.|...|.|.      .:..|:|
Zfish   149 AQNSVYSAGTSSWITGWGDIQAGVNLPAPGILQETMIPVVANDRCNALLGSG------TVTNNMI 207

  Fly   421 CAG-GELGRDTCTGDGGSAL---FCSIGGENSGVYEQAGIVNWGVGCGQEGIPAIYTEVSKFTNW 481
            ||| .:.|:|||.||.|..:   .|:       |:.||||.:||.||.....|.:||.||::.:|
Zfish   208 CAGLTQGGKDTCQGDSGGPMVTRLCT-------VWVQAGITSWGYGCADPNSPGVYTRVSQYQSW 265

  Fly   482 ITEKL 486
            |:.|:
Zfish   266 ISSKI 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SPH93	NP_609840.1	GRP	<136..189	CDD:254089
		Tryp_SPc	250..485	CDD:238113	79/245 (32%)
		Tryp_SPc	252..482	CDD:214473	77/240 (32%)
prss60.3	XP_002662541.2	Tryp_SPc	36..269	CDD:238113	81/252 (32%)
prss60.3	XP_002662541.2	Somatomedin_B	294..328	CDD:321959
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587627
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930